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| 1 | 冠状动脉内皮功能障碍患者循环MOTS-c水平下调显示文摘MOTS-c是一种新发现的线粒体衍生肽,其在调节代谢稳态中起作用。该研究旨在研究在没有显著冠状动脉结构性病变的患者中循环MOTS-c水平是否也与内皮功能障碍相关。方法:纳入无冠状动脉结构性病变的复发性心绞痛并接受冠状动脉造影和内皮功能检测的患者40例。 | Qin Q Delrio S Wan J Jay Widmer R Cohen P Lerman LO Lerman A 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，2： | 14 |
| 2 | 基于岩土介质三维孔隙结构的两相流模型显示文摘地下储层中岩土介质一般具有较低的孔隙连通性,宏观流动模拟一般忽略微观尺度的孔隙连通性,通过渗透率、弯曲度等参数反映储层的整体特性。但岩土介质的多孔性及孔隙间复杂的连通性,使得宏观描述流体在岩土介质中流动不能反映其内在流动特征。孔隙结构模型的建立可以反映岩土介质中孔隙的几何形态及空间连通性,为解释流体在复杂多孔介质中的流动特性提供有效手段。通过考虑岩土介质孔隙尺寸分布、孔隙孔喉空间相关性、孔隙连通性等特征参数,建立了反映不同岩土介质连通性、各向异性特征的等效孔隙网络模型。等效孔隙网络模型通过水力特征参数等效的方式反映岩土介质三维微观孔隙结构,通过渗透率计算验证了模型的有效性。此外,基于建立的孔隙结构模型,开发了孔隙尺度动态两相流计算模型,模型可以反映孔隙内弯液面的动态运动过程,直观反映多孔介质中的优势渗流,可以为不同孔隙尺度岩土介质提供表观渗透率、击穿曲线、相对渗透率曲线等宏观计算参数。将孔隙尺度两相流模型应用于页岩气开采中水力阻滞特性研究,结果表明:页岩基质的残余饱和度约为30%,随着平均配位数的增加,残余饱和度显著降低。 | 张鹏伟 胡黎明 Jay N Meegoda Michael A Celia | 2020 | 岩土工程学报2020，42，1： | 10 |
| 3 | 腰部的脊骨的磁性的回声成像上的过渡 lumbosacral 解剖的预言显示文摘 AIM:To evaluate two simple angle measurements for predicting lumbosacral transitional vertebra(LSTV) in magnetic resonance imaging(MRI) studies of the spine.METHODS:The lumbar spine MRI studies of 50 subjects with LSTV and 50 subjects with normal lumbosacral anatomy were retrospectively evaluated.In each study,the mid-sagittal T2-weighted image was used to measure the angle formed by a line parallel to the superior surface of the sacrum and a line perpendicular to the axis of the scan table(A-angle),as well as the angle formed by a line parallel to the superior endplate of the L3 vertebra and a line parallel to the superior surface of the sacrum(B-angle).RESULTS:The total study population consisted of 100 subjects(46 males,54 females,51 ± 16 years old).There were no differences in age and sex between the two groups.Both A-angle and B-angle were significantly increased in subjects with LSTV compared to controls(P < 0.05).The optimal cut-off values of A-angle and B-angle for the prediction of LSTV were 39.8°(sensitivity = 80%,specificity = 80%,accuracy = 83%;95% confidence interval = 74%-89%,P = 0.0001) and 35.9°(sensitivity = 80%,specificity = 54%,accuracy = 69%;95% confidence interval = 59%-78%,P = 0.0005),respectively.CONCLUSION:On sagittal MR images of the lumbar spine,an increased A-angle and/or B-angle should alert the radiologist to the presence of LSTV. | Majid Chalian Theodoros Soldatos John A Carrino Alan J Belzberg Jay Khanna Avneesh Chhabra | 2012 | World Journal of Radiology2012，4，3： | 5 |
| 4 | Clinical application of concentrated bone marrow aspirate in orthopaedics:A systematic review显示文摘AIM To examine the evidence behind the use of concentrated bone marrow aspirate(c BMA) in cartilage, bone, and tendon repair; establish proof of concept for the use of cB MA in these biologic environments; and provide the level and quality of evidence substantiating the use of cB MA in the clinical setting.METHODS We conducted a systematic review according to PRISMA guidelines. EMBASE, MEDLINE, and Web of Knowledge databases were screened for the use of cB MA in the repair of cartilage, bone, and tendon repair. We extracted data on tissue type, cB MA preparation, cB MA concentration, study methods, outcomes, and level of evidence and reported the results in tables and text.RESULTS A total of 36 studies met inclusion/exclusion criteria and were included in this review. Thirty-one of 36(86%) studies reported the method of centrifugation and preparation of cB MA with 15(42%) studies reporting either a cell concentration or an increase from baseline. Variation of c BMA application was seen amongst the studies evaluated. Twenty-one of 36(58%) were level of evidence Ⅳ, 12/36(33%) were level of evidence Ⅲ, and 3/36(8%) were level of evidence Ⅱ. Studies evaluated full thickness chondral lesions(7 studies), osteochondral lesions(10 studies), osteoarthritis(5 studies), nonunion or fracture(9 studies), or tendon injuries(5 studies). Significant clinical improvement with the presence of hyaline-like values and lower incidence of fibrocartilage on T2 mapping was found in patients receiving cB MA in the treatment of cartilaginous lesions. Bone consolidation and time to bone union was improved in patients receiving cB MA. Enhanced healingrates, improved quality of the repair surface on ultrasound and magnetic resonance imaging, and a decreased risk of re-rupture was demonstrated in patients receiving cB MA as an adjunctive treatment in tendon repair. CONCLUSION The current literature demonstrates the potential benefits of utilizing c BMA for the repair of cartilaginous lesions, bony defects, and tendon injuries in the clinical setting. This study also demonstrates discrepancies between the literature with regards to various methods of centrifugation, variable cell count concentrations, and lack of standardized outcome measures. Future studies should attempt to examine the integral factors necessary for tissue regeneration and renewal including stem cells, growth factors and a biologic scaffold. | Arianna L Gianakos Li Sun Jay N Patel Donald M Adams Frank A Liporace | 2017 | World Journal of Orthopedics2017，8，6： | 5 |
| 5 | A Model and Methodology for Hardware-software Codesign显示文摘 | Donald E T Jay K A Herman S | 1993 | IEEE Design & Test of Computers1993，10，3： | 2 |
| 6 | Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db / db Mice显示文摘 | Hong Chen Olga Charlat Louis A Tartaglia Elizabeth A Woolf Xun Weng Stephen J Ellis Nathan D Lakey Janice Culpepper Karen J More Roger E Breitbart Geoffrey M Duyk Robert I Tepper Jay P Morgenstern | 1996 | Cell1996，，3： | 2 |
| 7 | Advances in the Treatment and Outcome of Brainstem Cavernous Malformation Surgery: A Single-Center Case Series of 300 Surgically Treated Patients显示文摘 | Adib A Abla Gregory P Lekovic Jay D Turner Jean G de Oliveira Randall Porter Robert F Spetzler | 2011 | Neurosurgery2011，，2： | 2 |
| 8 | Intravitreal triamcinolone for refractory diabetic macular edema显示文摘 | Adam Martidis Jay S Duker Paul B Greenberg Adam H Rogers Carmen A Puliafito Elias Reichel Caroline Baumal | 2002 | Ophthalmology2002，，5： | 2 |
| 9 | A Tabu Search Heuristic Procedure for the Fixed Charge Transportation Problem 显示文摘 | Sun M H Jay E A | 1998 | European Journal of Operation Research1998，106，3： | 1 |
| 10 | MicroRNA profile analysis of human prostate canc- ers 显示文摘 | Tong A W Fulgham P Jay C Chen P Khalil I Liu S | 2009 | Cancer Gene Ther2009，16，： | 1 |
| 11 | Tidal asymmetry in an estuarine pycnoeline 1: Depth and thickness 显示文摘 | Cudaback C N Jay D A | 2000 | Journal of Geophysical Research2000，105，26： | 1 |
| 12 | New Developments in the Marine Nitrogen Cyc1e显示文摘 | Brandes Jay A Devol Allan H Deutsch Curtis | 2007 | Chemical Reviews2007，107，： | 1 |
| 13 | Guidelines for Conscious Sedation and Monitoring During Gastrointestinal Endoscopy显示文摘 | J.Patrick Waring Todd H Baron William K Hirota Jay L Goldstein Brian C Jacobson Jonathan A Leighton J.Shawn Mallery Douglas O Faigel | 2003 | Gastrointestinal Endoscopy2003，，3： | 1 |
| 14 | NKT cells in immunoregulation of tumor immunity: a new immunoregulatory axis 显示文摘 | Masaki T Jay A Berzofsky | 2007 | Trends Im- munol2007，28，11： | 1 |
| 15 | Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘 | Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H | 2008 | Plant Physiology2008，147，2： | 1 |
| 16 | Arabidopsis CAM7 and HY5 Physically Interact and Directly Bind to the HY5 Promoter to Regulate Its Expression and Thereby Promote Photomorpho- genesis显示文摘 | Nazial A Jay M Dhirodatta S | 2014 | PlantCell2014，26，3： | 1 |
| 17 | How Do Entrepreneurs Organize Firms Under Conditions of Uncertainty? 显示文摘 | Sharon A Alvarez Jay B Barney | 2005 | Journal of Management2005，31，5： | 1 |
| 18 | Prepubertal testiculartumors: our 10 years experience显示文摘 | Nerli RB A jay G Shivangouda P | 2010 | Indian J Cancer2010，47，3： | 1 |
| 19 | Fibroblast growth factor receptor tyrosine kinases :molecular analysis and signal transduction显示文摘 | Jaye M Schlessinger J Craig A | 1992 | Biochim Biophys Acta1992，1135，2： | 1 |
| 20 | Clinical significance of fever after percutaneous nephrolithotomy显示文摘 | JEFFREY A C ROLAND C JAY B | 1998 | Urology1998，52，1： | 1 |
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