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| 1 | Single vs dual(en bloc) kidney transplants from donors ≤ 5 years of age: A single center experience显示文摘AIM: To compare outcomes between single and dual en bloc(EB) kidney transplants(KT) from small pediatric donors. METHODS: Monocentric nonprospective review of KTs from pediatric donors ≤ 5 years of age. Dual EB KT was defined as keeping both donor kidneys attached tothe inferior vena cava and aorta, which were then used as venous and arterial conduits for the subsequent transplant into a single recipient. Donor age was less useful than either donor weight or kidney size in decision-making for kidney utilization as kidneys from donors < 8 kg or kidneys < 6 cm in length were not transplanted. Post-transplant management strategies were standardized in all patients.RESULTS: From 2002-2015, 59 KTs were performed including 34 dual EB and 25 single KTs. Mean age of donors(17 mo vs 38 mo, P < 0.001), mean weight(11.0 kg vs 17.4 kg, P = 0.046) and male donors(50% vs 84%, P = 0.01) were lower in the dual EB compared to the single KT group, respectively. Mean cold ischemia time(21 h), kidney donor profile index(KDPI; 73% vs 62%) and levels of serum creatinine(SCr, 0.37 mg/d L vs 0.49 mg/d L, all P = NS) were comparable in the dual EB and single KT groups, respectively. Actuarial graft and patient survival rates at 5-years follow-up were comparable. There was one case of thrombosis resulting in graft loss in each group. Delayed graft function incidence(12% dual EB vs 20% single KT, P = NS) was slightly lower in dual EB KT recipients. Initial duration of hospital stay(mean 5.4 d vs 5.6 d) and the one-year incidences of acute rejection(6% vs 16%), operative complications(3% vs 4%), and major infection were comparable in the dual EB and single KT groups, respectively(all P = NS). Mean 12 mo SCr and abbreviated MDRD levels were 1.17 mg/d L vs 1.35 mg/d L and 72.5 m L/min per 1.73 m^2 vs 60.5 m L/min per 1.73 m^2(both P = NS) in the dual EB and single KT groups, respectively. CONCLUSION: By transplanting kidneys from young pediatric donors into adult recipients, one can effectively expand the limited donor pool and achieve excellent medium-term outcomes. | Yousef Al-Shraideh Umar Farooq Hany El-Hennawy Alan C Farney Amudha Palanisamy Jeffrey Rogers Giuseppe Orlando Muhammad Khan Amber Reeves-Daniel William Doares Scott Kaczmorski Michael D Gautreaux Samy S Iskandar Gloria Hairston Elizabeth Brim Margaret Mangus Robert J Stratta | 2016 | World Journal of Transplantation2016，6，1： | 3 |
| 2 | Multifunctionality of the linker histones: an emerging role for protein-protein interactions显示文摘连接器 histones,例如, H1,最好为他们绑在 nucleosomes 并且稳定的能力被知道 nucleosome 结构和压缩高顺序的染色质结构。然而,多年以来,许多调查者报导了在涉及重要细胞的进程的连接器 histones 和蛋白质之间的特定的相互作用。这评论的目的为 H1 正在显示行动的一个重要其他的模式到热点证据,也就是蛋白质蛋白质相互作用。我们首先考察连接器 histone 行动的传统的看法的关键方面,包括 H1 C 终端领域的重要性。我们然后讨论和另外的蛋白质的连接器 histone 相互作用的知识的当前的状态,并且,在哪儿可能,加亮连接器的机制调停 histone 的蛋白质蛋白质相互作用。一起拿,数据为连接器 histones 建议一个组合角色,作为主要染色质两个都工作建筑上的蛋白质并且同时,作为招募,蛋白质的中心在存取并且修改染色质纤维包含了。 | Steven J McBryant Xu Lu Jeffrey C Hansen | 2010 | Cell Research2010，20，5： | 2 |
| 3 | The intracellular production and secetion of HIV-1 envelope protein in the methylotrophic yeast Pichia pastoris 显示文摘 | Carol A S Richard G B Jeffrey J C | 1993 | Gene1993，136，： | 2 |
| 4 | Nonirtherited risk factors and congenital cardiovascular defects 显示文摘 | Kathy J J Adolfo C Jeffrey A F | 2007 | Circulation2007，115，： | 1 |
| 5 | Decalcifica- tion shrinkage of cement paste显示文摘 | JEFFREY J C THOMAS J J JENNINGS H M | 2006 | Cem Concr Res2006，36，5： | 1 |
| 6 | The influence of hook size, type, and location on hook retention and survival of angled bonefish 显示文摘 | Jeffrey A S Aaron D S Steven J C | 2012 | Fisheries Research2012，113，1： | 1 |
| 7 | Qualitative and quantitative analysis of flavor additives on tobacco products using SPME - GC - Mass Spectroscopy显示文摘 | | 1997 | J Agric Food Chem1997，45，： | 1 |
| 8 | 显示文摘 | PETER C JEFFREY J E THOMAS J M | 1999 | Chem Rev1999，99，： | 1 |
| 9 | Derivation and comparison of SAR and frequency-wavenumber migration within a common inverse scalar wave problem formulation显示文摘 | Gilmore C Jeffrey I and LoVetri J | 2006 | IEEE Transactions on Geoscience and Remote Sensing2006，44，6： | 1 |
| 10 | Intranasal protollin^TM/F1- V vaccine elicits respiratory and serum antibody responses and protects mice against lethal aerosolizcd plague infection 显示文摘 | Taff J Jeffrey J A Sony L C | 2006 | Vaccine2006，24，： | 1 |
| 11 | Kinetic theories for granular Flow: inelastic particles in couette flow and slightly inelastic particles in a general flow field显示文摘 | Lun C K K Savage S B Jeffrey D J Chepueniy N | 1984 | J Fluid Mech1984，140，： | 1 |
| 12 | Silica aerogel films at ambient pressure显示文摘 | Sai S Prakash Jeffrey Brinker C Alan J Hurd | 1995 | Non-Cryst Solids1995，190，： | 1 |
| 13 | Maize HapMap2 identifies extant variation from a genome in flux 显示文摘 | Jer-Ming Chia Chi Song Peter J Bradbury Denise Cos- tich Natalia de Leon John Doebley Robert J Elshire Brandon Gaut Laura Geller Jeffrey C Glaubitz Michael Gore Kate E Guill Jim Holland Matthew B Hufford Jinsheng Lai Meng Li Xin Liu Yanli Lu Richard Mc- Combie Rebecca Nelson Jesse Poland Boddupalli M Prasanna Tanja Pyhajarvi Tingzhao Rong Rajandeep S Sekhon Qi Sun Maud I Tenaillon Feng Tian Jun Wang Xun Xu Zhiwu Zhang Shawn M Kaeppler Jef- frey Ross-lbarra Michael D McMullen Edward S Buck- ler Gengyun Zhang Yunbi Xu Doreen Ware | 2012 | Nat Genet2012，，44： | 1 |
| 14 | Managing Change toward Adaptive Water Management through Social Learning显示文摘 | Pahl-Wostl C Sendzimir J Jeffrey P | 2007 | Ecology and Society2007，12，2： | 1 |
| 15 | Hacmophilus pamsuis :Immunity in swine after vaccination 显示文摘 | RAPP V J GORDON J K JEFFREY T C | 1997 | Vet Med1997，92，： | 1 |
| 16 | Silica aerogel films at ambient pressure显示文摘 | Prakash Sai S Jeffrey Brinker C Alan J Hurd | 1995 | Non-Cryst Solids1995，190，： | 1 |
| 17 | Characterization of ovine nasal-associated lymphoid tissue and identification of M cells in the overlying follicle-associated epithelium显示文摘 | Stanley A C Huntley J F Jeffrey M | 2001 | Comp Pathol2001，125，4： | 1 |
| 18 | Growth variation and water mass associations of larva silver hake (Merluccius bilinearis) on the Scotian Shell显示文摘 | JEFFREY J A TAGGART C T | 2000 | Canadian Journal of Fisheries and Aquatic Sciences2000，57，8： | 1 |
| 19 | A Back propagation Neu- ral Network for Recognizing Fabric Defects 显示文摘 | Jeffrey K C F Lee C J | 2003 | Textile Research Journal2003，73，2： | 1 |
| 20 | Hae- mophilus parasuis :Immunity in swine after vaccination 显示文摘 | Rapp-Gabrielson V J Gordon J K Jeffrey T C | 1997 | Vet Med1997，92，7： | 1 |
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