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| 1 | High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate. | Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo | 2013 | World Journal of Gastroenterology2013，19，20： | 23 |
| 2 | Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS显示文摘 | Simon P Dunlop David Jenkins Keith R Neal Robin C Spiller | 2003 | Gastroenterology2003，，6： | 2 |
| 3 | A dynamic model for assessing the impact of coupled sulphur and nitrogen deposition scenarios on surface water acidification 显示文摘 | Jenkins A Ferrier R C Cosby B J | 1997 | Journal of Hydrology1997，197，： | 1 |
| 4 | A semi-quantitative method for measuring Crptosporidium parvum infection using polymerase chain reaction显示文摘 | Jenkins M Trout J Fayer R | 1997 | J Microbiol Methods1997，28，2： | 1 |
| 5 | Novel 1xN and NxN Integrated Optical Switches Using Self-lmaging Multimode GaAs/Al-GaAs Waveguides显示文摘 | Jenkins R M Heaton J M Wright D R Parker J T Birbeck J C H Smith G W Hilton K P | 1994 | Appl Phys Lett 71994，64，： | 1 |
| 6 | Steel fiber as shear reinforcement in beams显示文摘 | Baston GB Jenkins E Spatney R | 1972 | Journal of the American Concrete Institute Proceeding1972，69，10： | 1 |
| 7 | Arrays for protein expression profiling towards a viable alternative to two-dimensional gel electrophoresis?显示文摘 | Jenkins R E Pennington S R | 2001 | Proteomics2001，1，： | 1 |
| 8 | A taxonomy for multi-Agent robotics 显示文摘 | DUDEK G JENKIN M R M MILIOS E | 1996 | Autonomous Robots1996，4，3： | 1 |
| 9 | Combustion-properties of biomass 显示文摘 | Jenkins B M Baxter L L Miles T R | 1998 | Fuel Processing Technology1998，54，： | 1 |
| 10 | Flash method of determining thermal diffusivity, heat capacity and thermal conductivity显示文摘 | Paker W J Jenkins R J Butter C P | 1961 | J Appl Phys1961，32，9： | 1 |
| 11 | Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins显示文摘 | David R Borchelt Tamara Ratovitski Judy van Lare Michael K Lee Vicki Gonzales Nancy A Jenkins Neal G Copeland Donald L Price Sangram S Sisodia | 1997 | Neuron1997，，4： | 1 |
| 12 | Effects of future N deposition scenarios on the Galloway region of SW Scotland using a coupled sulfur and nitrogen model (MAGIC-WAND)显示文摘 | Ferrier R C Jenkins A Cosby B J | 1995 | Water Air and Soil Pollution1995，85，： | 1 |
| 13 | Spatial variability analysis of soil physical properties of alluvial soils 显示文摘 | IQBAL J THOMASSON J A JENKINS J N OWENS P R AND WHISLER F D | 2005 | Soil Science Society of America Journal2005，69，： | 1 |
| 14 | The influence of thermokarst disturbance on the water quality of small upland lakes, Mackenzie delta region, northwest territories, Canada 显示文摘 | Kokelj S V Jenkins R E Milburn D | 2005 | Permafrost and Periglacial Processes2005，16，： | 1 |
| 15 | Absorptance, Emittance, and Thermal Efficiencies of Surfaces for Solar Spacecraft Power显示文摘 | BUTLER C P JENKINS R J PARKER W J | 1964 | Solar Energy1964，8，1： | 1 |
| 16 | Management choices for the dif- ficult airway by anesthesiologists in Canada显示文摘 | Jenkins K Wang DT Correa R | 2002 | Can J Anaesth2002，49，： | 1 |
| 17 | Addressing suicide as a public-health problem 显示文摘 | Jenkins R | 2002 | Lancet2002，359，9309： | 1 |
| 18 | Rheologlcal properties of semidilute hydrophobically modified alkali-soluble emul- sion polymers in sodium dodecyl sulfate and salt solutions 显示文摘 | Tan H Tam K C Jenkins R D | 2000 | Langmuir2000，16，13： | 1 |
| 19 | The development of a multitarget,multicolor fluo- rescence in situ hybridization assay {or the detection of urothelial carcinoma in urine显示文摘 | SOKOLOVA I A HALLING K C JENKINS R B | 2000 | J Mol Diagn2000，2，： | 1 |
| 20 | Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy显示文摘 | Krupa A Jenkins R Luo DD | 2010 | J Am Soc Nephrol2010，21，3： | 1 |
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