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1篇 您的检索式:作者名="Jennifer LMcQuade"
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1Body mass index and survival after cancer diagnosis:A pan-cancer cohort study of 114430 patients with cancer显示文摘The recommendation encouraging patients with cancer to keep a normal body mass index(BMI)is largely extrapolated from data on risk of developing cancer.We tested the prospective association between peri-diagnostic(within 1 year post-diagnosis)BMI and all-cause mortality in patients with incident cancers.During 7.2 years of follow-up,42%(48,340)of the 114430 patients with cancer died.Spline analysis revealed that compared with a BMI of 22.5,a BMI lower than 22.5 was associated with increased risk of all-cause mortality across 24 cancer types.A BMI higher than 22.5 was associated with reduced all-cause mortality,while a non-linear association was observed;the lowest risk was found at a BMI of 29.6–34.2,and the risk started to return to and above unity at very high BMI values.The reduced mortality risk of high BMI was observed in 23 of 24 cancer types and maintained after attempts to remove potential selection bias,confounding by smoking and comorbidities,and reserve causality.Huakang Tu Jennifer LMcQuade Michael ADavies Maosheng Huang Kunlin Xie Yuanqing Ye Wong-Ho Chow Alma Rodriguez Xifeng Wu 2022The Innovation2022,3,6:0
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