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| 1 | Actions of human telomerase beyond telomeres显示文摘Telomerase 由维持 telomere 动态平衡和正直在绕过细胞的老化并且在癌症前进有基本角色。然而,最近的研究导致了一些调查者在没有它的很好确定的功能的明显的参与,在 telomere 维护表明小径的几个必要房间建议 telomerase 的新奇生物化学的性质。这些观察可以进一步在老化和癌症提高我们 telomerase 的分子的行动的理解。这评论将在 apoptosis 在 telomerase 的课外活动提供更改, DNA 修理,干细胞功能,并且在基因表示的规定。 | Yusheng Cong Jerry W Shay | 2008 | Cell Research2008,18,7: | 36 |
| 2 | Establishing minimum clinically important difference values for the Patient-Reported Outcomes Measurement Information System Physical Function, hip disability and osteoarthritis outcome score for joint reconstruction, and knee injury and osteoarthritis out显示文摘AIM To establish minimum clinically important difference(MCID) for measurements in an orthopaedic patient population with joint disorders.METHODS Adult patients aged 18 years and older seeking care for joint conditions at an orthopaedic clinic took the Patient-Reported Outcomes Measurement Information System Physical Function(PROMIS~? PF) computerized adaptive test(CAT), hip disability and osteoarthritis outcome score for joint reconstruction(HOOS JR), and the knee injury and osteoarthritis outcome score for joint reconstruction(KOOS JR) from February 2014 to April 2017. MCIDs were calculated using anchorbased and distribution-based methods. Patient reports of meaningful change in function since their first clinic encounter were used as an anchor.RESULTS There were 2226 patients who participated with a mean age of 61.16(SD = 12.84) years, 41.6% male, and 89.7% Caucasian. Mean change ranged from 7.29 to 8.41 for the PROMIS~? PF CAT, from 14.81 to 19.68 for the HOOS JR, and from 14.51 to 18.85 for the KOOS JR. ROC cut-offs ranged from 1.97-8.18 for the PF CAT, 6.33-43.36 for the HOOS JR, and 2.21-8.16 for the KOOS JR. Distribution-based methods estimated MCID values ranging from 2.45 to 21.55 for the PROMIS~? PF CAT; from 3.90 to 43.61 for the HOOS JR, and from 3.98 to 40.67 for the KOOS JR. The median MCID value in the range was similar to the mean change score for each measure and was 7.9 for the PF CAT, 18.0 for the HOOS JR, and 15.1 for the KOOS JR.CONCLUSION This is the first comprehensive study providing a wide range of MCIDs for the PROMIS? PF, HOOS JR, and KOOS JR in orthopaedic patients with joint ailments. | Man Hung Jerry Bounsanga Maren W Voss Charles L Saltzman | 2018 | World Journal of Orthopedics2018,9,3: | 3 |
| 3 | Association of types of diabetes and insulin dependency on birth outcomes显示文摘BACKGROUND Diabetes rates among pregnant women in the United States have been increasing and are associated with adverse pregnancy outcomes.AIM To investigate differences in birth outcomes(preterm birth,macrosomia,and neonatal death)by diabetes status.METHODS Cross-sectional design,using linked Missouri birth and death certificates(singleton births only),2010 to 2012(n=204057).Exposure was diabetes non-diabetic,pre-pregnancy diabetes-insulin dependent(PD-I),pre-pregnancy diabetes-non-insulin dependent(PD-NI),gestational diabetes-insulin dependent(GD-I),and gestational diabetes-non-insulin dependent(GD-NI).Outcomes included preterm birth,macrosomia,and infant mortality.Confounders included demographic characteristics,adequacy of prenatal care,body mass index,smoking,hypertension,and previous preterm birth.Bivariate and multivariate logistic regression assessed differences in outcomes by diabetes status.RESULTS Women with PD-I,PD-NI,and GD-I remained at a significantly increased odds for preterm birth(aOR 2.87,aOR 1.77,and aOR 1.73,respectively)and having a very large baby[macrosomia](aOR 3.01,aOR 2.12,and aOR 1.96,respectively);in reference to non-diabetic women.Women with GDNI were at a significantly increased risk for macrosomia(aOR1.53),decreased risk for their baby to die before their first birthday(aOR 0.41)and no difference in risk for preterm birth in reference to non-diabetic women.CONCLUSION Diabetes is associated with the poor birth outcomes.Clinical management of diabetes during pregnancy and healthy lifestyle behaviors before pregnancy can reduce the risk for diabetes and poor birth outcomes. | Pamela K Xaverius Steven W Howard Deborah Kiel Jerry E Thurman Ethan Wankum Catherine Carter Clairy Fang Romi Carriere | 2022 | World Journal of Clinical Cases2022,10,7: | 2 |
| 4 | Fractal Analysis for Morphological Description of Corn Roots under Nitrogen Stress显示文摘 | Bahman E John R S Jerry W M | 1993 | Agronomy Journal1993,85,: | 1 |
| 5 | Are mitochondrial DNA mutations involved in the carcinogenic proeess?显示文摘 | JERRY WS HAROLD W | 1987 | Murat Res1987,186,: | 1 |
| 6 | Finite element analysis of vehicle-bridge interaction 显示文摘 | Leslaw K Hongyi L Jerry W | 2006 | Finite Elements in Analysis and Design2006,42,12: | 1 |
| 7 | Ethanolysis of seed oil in flowing supercritical carbon dioxide 显示文摘 | Michael A Jackson Jerry W King | 1996 | J Am Oil Chem Soc1996,73,: | 1 |
| 8 | Targeting telomerase-expressing cancer cells显示文摘 | Michel M O Woodring E W Jerry W S | 2011 | Journal of cellular and molecular medicine2011,15,7: | 1 |
| 9 | Cytokine specific ELISPOT assay single cell analysis of IL-2,IL-4 and IL-6 producing cells显示文摘 | Kohtaro F Jerry RM Kenneth W | 1993 | J Immunol Methods1993,160,: | 1 |
| 10 | High temperature lead-free solder for microelectronics 显示文摘 | Framl W Gau e Gary Becka Jerry Badgett | 2001 | J Electron Mater2001,,6: | 1 |
| 11 | Cytokine specific ELISPOT assay single cell analysis of IL-2,IL-4 and IL-6 producing cells显示文摘 | Kohtaro F Jerry RM Kenneth W | 1993 | J Immunol Methods1993,160,: | 1 |
| 12 | Maranville root development and nitrogen influx of corn genotypes grown under combined drought and N stress显示文摘 | BAHMAN E JERRY W | 1993 | Agron J1993,85,: | 1 |
| 13 | Pest-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication 显示文摘 | Jerry P Nolan J Robert W | 2008 | Resuscitation2008,,79: | 1 |
| 14 | Association of RIG- I with innate immunity of ducks to influenza显示文摘 | Megan R W Jerry R A Robert G W | 2010 | PNAS2010,107,13: | 1 |
| 15 | Subcritical Solvent Extraction of Anthocyanins from Dried Red Grape Pomace显示文摘 | Jeana K Monrad Luke R Howard Jerry W King | | 0,,07: | 1 |
| 16 | Size as a parameter for solvent effects on Candida antarctica lipase B enantioselectivity显示文摘 | Linda Fransson Jerry W King | 2002 | Biochimical et Biophysica Acta (BBA)-Protein Structure and Molecular Enzymology2002,1594,2: | 1 |
| 17 | Supercritical fluid extraction and chromatography for fat-soluble vitamin analysis显示文摘 | Charlotta Turner Jerry W King Lennart Mathiasson | 2001 | Journal of Chromatography A2001,,1: | 1 |
| 18 | Dissociated effects of misoprostol gastric acid secretion and mucosal blood flow显示文摘 | Felix W Leung Jerry C Miller Paul H Guth | 1986 | Dig Dis Sci1986,31,: | 1 |
| 19 | Alkaloids from Cephalotaxus drupacea and Cephalotaxus fortunei显示文摘 | William W Gerald I Jerry McKay | 1963 | J Org Che1963,28,9: | 1 |
| 20 | Role of antioxidants and trace elements in health and immunity of transition dairy cows显示文摘 | Jerry W William P W | 2008 | The Veterinary Journal2008,176,1: | 1 |