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3篇 您的检索式:作者名="Jiang Zhesheng"
    题名 作者 年代 出处 被引量
1The effect of anodizing temperature on the structure and electrical properties of Al-Ti composite oxide film显示文摘The Al-Ti composite oxide films with high dielectric constant were prepared by hydrolysis precipitation and anodizing. The growth, structure and electrical properties of the Al-Ti composite oxide films formed at different anodizing temperatures from 25℃ to 85℃ have been studied by dissolution of anodic oxide films, Auger electron spectroscopy (AES), and electrical measurements. With the anodizing temperature increasing, the film growth rate increases, the structure of two layers in the Al-Ti composite oxide film converts into three layers, I-V characteristics change evidently, and the specific capacitance achieves a peak value at about 75℃. The local breakdown in the composite oxide films formed at 50℃ occurs obviously, which may be contributed to the lowest leakage current and the highest withstanding voltage.CHEN Jinju YANG Bangchao JIANG Meilian FENG Zhesheng 2005Science China(Technological Sciences)2005,48,6:2
2GLUL stabilizes N-Cadherin by antagonizing β-Catenin to inhibit the progresses of gastric cancer显示文摘Glutamate-ammonia ligase(GLUL, also known as glutamine synthetase) is a crucial enzyme that catalyzes ammonium and glutamate into glutamine in the ATP-dependent condensation. Although GLUL plays a critical role in multiple cancers, the expression and function of GLUL in gastric cancer remain unclear. In the present study, we have found that the expression level of GLUL was significantly lower in gastric cancer tissues compared with adjacent normal tissues, and correlated with N stage and TNM stage, and low GLUL expression predicted poor survival for gastric cancer patients. Knockdown of GLUL promoted the growth, migration, invasion and metastasis of gastric cancer cells in vitro and in vivo, and vice versa, which was independent of its enzyme activity. Mechanistically, GLUL competed with β-Catenin to bind to N-Cadherin, increased the stability of N-Cadherin and decreased the stability of β-Catenin by alerting their ubiquitination. Furthermore, there were lower N-Cadherin and higher β-Catenin expression levels in gastric cancer tissues compared with adjacent normal tissues. GLUL protein expression was correlated with that of N-Cadherin, and could be the independent prognostic factor in gastric cancer. Our findings reveal that GLUL stabilizes N-Cadherin by antagonizing β-Catenin to inhibit the progress of gastric cancer.Qiwei Jiang Yong Li Songwang Cai Xingyuan Shi Yang Yang Zihao Xing Zhenjie He Shengte Wang Yubin Su Meiwan Chen Zhesheng Chen Zhi Shi 2024Acta Pharmaceutica Sinica B2024,14,2:0
3Speed up the Retrofit of Thermal Power Generating Units, Raise the Effectiveness of Power Plant Comprehensively显示文摘Jiang Zhesheng 2000Electricity2000,,1:0
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