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您的检索式：作者名="Jianhao Yin"
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| 1 | Perylenediimide chromophore as an efficient photothermal agent for cancer therapy显示文摘Photothermal agents with improved bioavailabilities can generate heat from near-infrared light, which has been efficiently used for in vivo photothermal therapy(PTT) for cancer, with minimum tissue invasion. Strategies for developing organic near-infrared-absorbing molecules for photothermal cancer therapy have drawn intensive attention among academic investigators. However, conventional organic nearinfrared-absorbing molecules may not only have complex synthesis procedures, but also easily suffer from photobleaching under light irradiation. These drawbacks might lead to an increase in the synthesis cost, and elicit a risk of side effects in PTT. Thus, it is essential to devise an organic photothermal agent with stable photothermal capacity, which involves a facile synthesis process. In this study, incorporating a secondary amine group(donor) in the bay regions of perylenediimides(PDIs) could lead to a 150-nm bathochromic shift of the absorption maximum. Next, a modification of poly(ethylene glycol)(PEG) at the periphery of the chromophore renders the targeted macromolecule PDI-PEG highly water-soluble,and capable of intense absorption in the near-infrared region. The self-assembled PDI-based nanoparticles(PDI-NPs) have a size of 55 nm in aqueous solutions. PDI-NPs with excellent photostability possess a high photothermal conversion efficiency of up to 43% ± 2%. Finally, PDI-NPs allow for efficient in vitro and in vivo photothermal cancer therapy. Meanwhile, PDI-NPs exhibit quite low cytotoxicity and no biotoxicity on major organs in vivo. Thus, these easily-manufactured PDI-NPs can serve as extremely stable photothermal agents for efficient photothermal cancer therapy. | Shaobo Zhang Jianhao Li Jie Wei Meizhen Yin | 2018 | Science Bulletin2018，63，2： | 1 |
| 2 | Mechanical strength and the degradation mechanism of metakaolin based geopolymer mixed with ordinary Portland cement and cured at high temperature and high relative humidity显示文摘Geopolymer is a new type of eco-friendly cementitious material, and its superior drying and high temperature resistance has been widely recognized. The service performance of geopolymer under 150 ℃ high-temperature hydrothermal conditions is still less discussed. In this paper, the mechanical strength of pure metakaolin system with low calcium content and metakaolin-cement system with high calcium content under hydrothermal and non-hydrothermal conditions were studied. The results show that under 150 ℃ hydrothermal conditions, the strength of pure metakaolin geopolymer sharply decreases by reduction rate of 81.8% compared to the sample under 150 ℃ drying conditions, while the strength of metakaolin-cement geopolymers is well retained with only a slight decrease of 14.4%. This is mainly because the predominantly hydration product sodium aluminosilicate(N-A-S-H) gel of pure metakaolin system undergoes the process of “dissociation–repolymerization–crystallization” under 150 ℃ hydrothermal conditions, resulting in the loss of cementation ability and obvious deterioration of mechanical strength. In the metakaolin-cement system, the high-calcium calcium silicate gel(C-A-S-H)gel maintains a stable structure, thereby maintaining the macroscopic strength of the material under the hydrothermal conditions. | Xia Miao Xiaofan Pang Shiyu Li Haoguang Wei Jianhao Yin Xiangming Kong | 2023 | Chinese Journal of Chemical Engineering2023，60，8： | 0 |
| 3 | Dinitrogen Activation of Cyclopentadienyl-Phosphine–Iron Complexes of Three Different Valences显示文摘A series of structurally well-defined iron-dinitrogen complexes(LFe-N2)bearing cyclopentadienylphosphine ligands(L)were synthesized and analyzed by single-crystal X-ray structural analysis,IR/Raman spectra,magnetometry,Mössbauer spectroscopy,and elemental analysis.The conversion relationship and the change of the spin states among the iron complexes with different valences were studied in detail. | Gao-Xiang Wang Jianhao Yin Jiapeng Li Zhu-Bao Yin Botao Wu Junnian Wei Wen-Xiong Zhang Zhenfeng Xi | 2021 | CCS Chemistry2021，3，12： | 0 |
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