维普中文期刊产品整合服务
1篇 您的检索式:作者名="Jiazhe Luo"
    题名 作者 年代 出处 被引量
1Terbium-doped zinc oxide constructed dual-light-responsive nitric oxide-releasing platform for bacterial keratitis treatment显示文摘Bacterial keratitis(BK)is a principal factor contributing to corneal ulcers and ocular complications,and has become a significant killer of global vision health.Traditional antibiotic therapy has unsatisfactory therapeutic effect due to short residence time and low utilization rate of drug,and the long-term abuse of antibiotics can easily incur the prevalence of drug-resistant bacteria.Furthermore,antibiotics are not effective in addressing the excessive inflammatory response caused by infection.Here,we developed a terbium-doped zinc oxide constructed dual-light-responsive nitric oxide(NO)-releasing nanoparticle(ZT@P@B)and modified it on the surface of contact lenses(CL-ZT@P@B)to boost its bioavailability.In vitro and in vivo experimental results verified that ZT@P@B could simultaneously respond to green light(GL)and 808 nm near-infrared(NIR)without obvious damage to the eyes,releasing reactive oxygen species(ROS)and NO,which could effectively kill bacteria(including drug-resistant strains)and reduce inflammatory response.The platform provides a promising strategy for the prevention and treatment of BK.Yue Sun Wei Zhang Menghui Wang Huijie Liu Qun Li Jiazhe Luo Mengzhen Zhao Shichen Liu Xiaolei Wang 2023Nano Research2023,16,1:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费