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| 1 | 健康老年妇女近段股骨骨密度和结构的定量CT研究显示文摘目的采用定量CT(QCT)和双能X线吸收测量(DXA)仪对健康老年妇女近段股骨骨密度(BMD)和骨结构进行研究,并对2种测量方法的结果进行比较。方法对66名65岁以上健康妇女左侧髋关节进行DXA测量,计算出股骨颈和粗隆区BMD;对其双侧近段股骨进行QCT测量,计算出股骨颈、粗隆区和整体股骨ROI的皮质骨、松质骨和总体骨的BMD和体积;并将QCT三维图像模拟DXA的平面投影计算出模拟DXA股骨颈BMD和模拟DXA股骨粗隆区BMD。对所获数据进行配对t检验或非参数秩和检验,并用Pearson法分析DXA和QCT相对应ROI的相关性。结果用QCT可以对股骨近段不同ROI(股骨颈、粗隆区和整体股骨区)及不同骨成分(皮质骨、松质骨和总体骨)的BMD及体积等参数进行精确的定量分析。除右侧股骨颈皮质骨BMD[(0.52±0.04)g/cm^3]、股骨粗隆区皮质骨BMD[(0.49±0.03)g/cm^3]、股骨粗隆区综合骨BMD[(0.22±0.04)g/cm^3]大于左侧相应参数[分别为[(0.51±0.04)、(0.48±0.03)、(0.21±0.04)g/cm^3],差异均有统计学意义(P值均〈0.05),但差别均〈3.3%;而模拟DXA股骨颈BMD、模拟DXA股骨粗隆区BMD、股骨颈皮质骨体积、股骨颈松质骨BMD、股骨颈松质骨体积、股骨颈综合骨BMD、股骨颈综合骨体积、股骨粗隆区皮质骨体积、股骨粗隆区松质骨BMD、股骨粗隆区松质骨体积、股骨粗隆区综合骨体积左侧参数分别为(0.52±0.10)g/cm^2、(0.78±0.13)g/cm^2、5.80cm^3、(0.06±0.03)g/cm^3、(5.19±1.40)cm^3、(0.25±0.04)g/cm^3、15.66cm^3、(21.74±3.43)cm^3、(0.08±0.03)g/cm^3、(34.27±6.09)cm^3、(76.12±11.11)cm^3,右侧分别为(0.52±0.10)g/cm^2、(0.78±0.13)g/cm^2、6.01cm^3、(0.06±0.02)g/cm^3、(5.17±1.27)cm^3、(0.25±0.04)g/cm^3、15.62cm^3、(22.12±3.60)cm^3、(0.09±0.03)g/cm^3、(34.17±5.94)cm^3、(76.53±10.71)cm^3,差异均无统计学意义(P值均〉0.05)。左右两侧近段股骨QcT各相对应参数之间的r值范围在0.656~0.955,均具有相关性(P〈0.05)。QcT模拟DXA股骨颈和粗隆区BMD与真正DXA测量的相应值之间r值分别为0.685和0.855,具有相关性(P〈0.05)。结论利用QCT技术可以对老年妇女近段股骨不同区域和不同成分的BMD和结构进行精确定量分析,QCT是骨质疏松研究中非常有用的测量技术。 | 程晓光 Li Jing 刘霞 王予生 李谨 屈辉 H Genant T Lang | 2009 | 中华放射学杂志2009，43，2： | 8 |
| 2 | Hematological disorders and pulmonary hypertension显示文摘Pulmonary hypertension(PH),a serious disorder with a high morbidity and mortality rate,is known to occur in a number of unrelated systemic diseases.Several hematological disorders such as sickle cell disease,thalassemia and myeloproliferative diseases develop PH which worsens the prognosis.Associated oxidant injury and vascular inflammation cause endothelial damage and dysfunction.Pulmonary vascular endothelial damage/dysfunction is an early event in PH resulting in the loss of vascular reactivity,activation of proliferative and antiapoptotic pathways leading to vascular remodeling,elevated pulmonary artery pressure,right ventricular hypertrophy and premature death.Hemolysis observed in hematological disorders leads to free hemoglobin which rapidly scavenges nitric oxide(NO),limiting its bioavailability,and leading to endothelial dysfunction.In addition,hemolysis releases arginase into the circulation which converts L-arginine to ornithine,thus bypassing NO production.Furthermore,treatments for hematological disorders such as immunosuppressive therapy,splenectomy,bone marrow transplantation,and radiation have been shown to contribute to the development of PH.Recent studies have shown deregulated iron homeostasis in patients with cardiopulmonary diseases including pulmonary arterial hypertension(PAH).Several studies have reported low iron levels in patients with idiopathic PAH,and iron deficiency is an important risk factor.This article reviews PH associated with hematological disorders and its mechanism:and iron homeostasis and its relevance to PH. | Rajamma Mathew Jing Huang Joseph M Wu John T Fallon Michael H Gewitz | 2016 | World Journal of Cardiology2016，8，12： | 6 |
| 3 | Detection of low observable target within sea clutter by structure function based multifractal analysis显示文摘 | Jing H Wenwen T Gao J B | 2006 | IEEE Transaction on Antennas and Propagation2006，54，1： | 1 |
| 4 | Metal porphyrin/phenyltrimethylammonium tribromidc:High efficient catalysts for coupling reaction of CO2 and epoxides显示文摘 | JIN L L JING H W CHANG T | 2007 | Journal of Molecular Catalysis(A) : Chemical2007，261，： | 1 |
| 5 | Local structure based supervised feature extraction 显示文摘 | ZHAO H T SUN S Y JING Z L | 2006 | Pattern Reognition2006，39，88： | 1 |
| 6 | Fuzzy-decisionmaking problems of fuel ethanol production using a genetically engineered yeast显示文摘 | Wang F S Jing C H Tsao G T | 1998 | Industrial & Engineering Chemistry Research1998，37，8： | 1 |
| 7 | Anal Chim Acta显示文摘 | Jing T Xia H Guan Q Lu W H Dai Q Niu J W Lim J M Hao Q L Lee Y Zhou Y K Mei S R | 2011 | 692:732011，692，： | 1 |
| 8 | Ephrin-A1-mediated dopaminergic neurogenesis and angiogenesis in a rat model of Parkinson's disease显示文摘 | Jing X Miwa H Sawada T | 2012 | PLo S One2012，7，32： | 1 |
| 9 | Magnetic molecularly imprinted nanoparticles for recognition of lysozyme显示文摘 | Jing T Du H Dai Q | 2010 | Biosensors and Bioelectronics2010，26，2： | 1 |
| 10 | Sensitization and apoptosis augmentation of K562/ADM cells by anti-multidrug resistance gene peptide nucleic acid and antisense oligodeoxyribonucleotide 显示文摘 | Wei H L Wu Y J Jing T | 2003 | Acta Pharmacol Sin2003，24，8： | 1 |
| 11 | 查看详情显示文摘 | Jing Y Ohizumi H Kawazoe N Hashimoto S Masuda Y Nakajo S Yoshida T Kuroiwa Y Nakaya K | | 0，，6： | 1 |
| 12 | 显示文摘 | Wang J J Jing Y H Ouyang T | 2015 | Catalysis Communica-tions2015，59，： | 1 |
| 13 | Consumer Trust in E-commerce in the United States, Singapore and China 显示文摘 | Thompson S H T Jing L | 2007 | Omega:The International Journal of Management Science2007，35，1： | 1 |
| 14 | Fuzzy-decision-making problems of fuel ethanol production using a genetically engineered yeast显示文摘 | WANG F S JING C H TSAO G T | 1998 | Industrial & Engineering Chemistry Research1998，37，8： | 1 |
| 15 | Effectiveness of different central venous catheters for catheter-related infections:a network meta-analysis显示文摘 | WANG H HUANG T JING J | 2010 | J Hosp Infect2010，76，1： | 1 |
| 16 | Proteomics approach to identify wound-response related proteins from rice leaf sheath显示文摘 | Shen S H Jing Y X Kueng T Y | 2003 | Proteomics2003，3，： | 1 |
| 17 | Time-resolved dynamic tensile spallation of pure aluminum under laser irradiation显示文摘 | Wang Y G He H L Wang L L Jing F Q Boustie M Sekine T | 2006 | Journal of Applied Physics2006，100，03： | 1 |
| 18 | Predicting the ballistic limit for plain woven glass/epoxy composite laminate显示文摘 | Jenq S T Jing H S Chung Charles | 1994 | Internat J lmpact Engineering1994，15，4： | 1 |
| 19 | Proteomics approach to identify wound response related proteins from rice leaf sheath显示文摘 | SHEN S H JING Y X KUANG T Y | 2003 | Proteomics2003，，3： | 1 |
| 20 | Detection of Low Observable Targets Within Sea Clutter by Structure Function Based Multifractal Analysis显示文摘 | Jing H Wenwen T Jianbo G | 2006 | IEEE Trans on Antennas and Propagation2006，54，1： | 1 |
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