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| 1 | Synthesis of polycrystalline γ-AlON powders by novel wet chemical processing显示文摘The synthesis of polycrystalline aluminum oxynitride (AlON) powders was investigated by the carbothermal reduction and nitridation (CRN) of amorphous precursor obtained by wet chemical processing. Co-precipitation processing was employed to achieve amorphous precursor from Al(NO3)3 solution dispersed by nanosized carbon particles, which was composed of Al(OH)3 and C particles homogeneously. The effects of the content of carbon black, pH value, and calcination temperature on formation of AlON phase were investigated by means of XRD, SEM and TEM, respectively. It was found that single phase AlON powder could be synthesized when the resultant precursors were calcined at 1750°C for 2 hours under flowing N2 . Under optimal additional content of C (5.6wt%), the resultant AlON powders exhibited the primary particle size of about 1-3 μm with a specific surface area of 3.2m2/g, which were superior to that of carbothermal reduction of immediate mixture of γ-Al2O3/C powders. | LEI JingXuan MA FeiZhong SHI Ying XIE JianJun HU Wei SHI ZhiWei | 2012 | Science China(Technological Sciences)2012，55，12： | 4 |
| 2 | Mining authorship characteristics in bug repositories显示文摘Bug reports are widely employed to facilitate software tasks in software maintenance. Since bug reports are contributed by people, the authorship characteristics of contributors may heavily impact the performance of resolving software tasks. Poorly written bug reports may delay developers when fixing bugs. However,no in-depth investigation has been conducted over the authorship characteristics. In this study, we first leverage byte-level N-grams to model the authorship characteristics and employ Normalized Simplified Profile Intersection(NSPI) to identify the similarity of the authorship characteristics. Then, we investigate a series of properties related to contributors' authorship characteristics, including the evolvement over time and the variation among distinct products in open source projects. Moreover, we show how to leverage the authorship characteristics to facilitate a well-known task in software maintenance, namely Bug Report Summarization(BRS). Experiments on open source projects validate that incorporating the authorship characteristics can effectively improve a stateof-the-art method in BRS. Our findings suggest that contributors should retain stable authorship characteristics and the authorship characteristics can assist in resolving software tasks. | He JIANG Jingxuan ZHANG Hongjing MA Najam NAZAR Zhilei REN | 2017 | Science China(Information Sciences)2017，60，1： | 1 |
| 3 | Long-term and short-term stability characteristics of receiver inter system bias for BDS3/BDS2显示文摘The study of inter-system bias(ISB)is important for multi-system fusion and the performance of different signal compatibility.In this paper,the stability of ISB at the BDS3/BDS2 receiver end is calculated and analyzed for different time spans(DOY 060~090 in 2021)from a total of 31 MGEX and iGMAS stations.We adopted two estimation strategies,random walk and constant approach,using the precision products of orbit and clock bias provided by WUM,the influence of which on ISB was also analyzed.Our results showed that the ISB value varied little within a day,and the mean of daily ISB standard deviation was only 0.037 m when the observation condition was good.The signal reception was continuous,indicating a high ISB stability for one day.If extending the time series to one month,however,the ISB standard deviation calculated by constant approach,in which a constant ISB is estimated on a daily basis was about 0.1 m,and the results of adjacent days were not continuous,with no apparent pattern.Concerning the random walk approach,the obtained ISB time series also had a jump,and the conclusion was the same as that of the constant strategy.Besides,receiver types showed a strong regularity in ISB numerical situation,and the distribution of ISB values corresponding to the same receiver type was relatively close.Therefore,we conclude that the ISB parameters remain stable in the short term(one day)and less stable in the long-term period.It is recommended that the ISB term should be set as a constant estimate every day in BDS3/BDS2 solutions,regardless of receiver type consistency. | Jingxuan Guo Weiping Jiang Yan Chen Xincheng Ma Hua Chen | 2023 | Geodesy and Geodynamics2023，14，2： | 0 |
| 4 | Electric-controlled pressure relief valve for enhanced safety in liquid-cooled lithium-ion battery packs显示文摘The liquid-cooled battery energy sto rage system(LCBESS) has gained significant attention due to its superior thermal management capacity.However,liquid-cooled battery pack(LCBP) usually has a high sealing level above IP65,which can trap flammable and explosive gases from battery thermal runaway and cause explosions.This poses serious safety risks and challenges for LCBESS.In this study,we tested overcharged battery inside a commercial LCBP and found that the conventionally mechanical pressure relief valve(PRV) on the LCBP had a delayed response and low-pressure relief efficiency.A realistic 20-foot model of an energy storage cabin was constructed using the Flacs finite element simulation software.Comparative studies were conducted to evaluate the pressure relief efficiency and the influence on neighboring battery packs in case of internal explosions,considering different sizes and installation positions of the PRV.Here,a newly developed electric-controlled PRV integrated with battery fault detection is introduced,capable of starting within 50 ms of the battery safety valve opening.Furthermore,the PRV was integrated with the battery management system and changed the battery charging and discharging strategy after the PRV was opened.Experimental tests confirmed the efficacy of this method in preventing explosions.This paper addresses the safety concerns associated with LCBPs and proposes an effective solution for explosion relief. | Yuhang Song Jidong Hou Nawei Lyu Xinyuan Luo Jingxuan Ma Shuwen Chen Peihao Wu Xin Jiang Yang Jin | 2024 | Journal of Energy Chemistry2024，90，3： | 0 |
| 5 | Seco-cyclic phorbol derivatives and their anti-HIV-1 activities显示文摘Phorbol esters are recognized for their dual role as anti-HIV-1 agents and as activators of protein kinase C(PKC).The efficacy of phorbol esters in binding with PKC is attributed to the presence of oxygen groups at positions C20,C3/C4,and C9 of phorbol.Concurrently,the lipids located at positions C12/C13 are essential for both the anti-HIV-1 activity and the formation of the PKC-ligand complex.The influence of the cyclopropane ring at positions C13 and C14 in phorbol derivatives on their anti-HIV-1 activity requires further exploration.This research entailed the hydrolysis of phorbol,producing seco-cyclic phorbol derivatives.The anti-HIV-1 efficacy of these derivatives was assessed,and the affinity constant(Kd)for PKC-δprotein of selected seco-cyclic phorbol derivatives was determined through isothermal titration calorimetry.The findings suggest that the chemical modification of cyclopropanols could affect both the anti-HIV-1 activity and the PKC binding affinity.Remarkably,compound S11,with an EC50 of 0.27μmol·L^(−1) and a CC50 of 153.92μmol·L^(−1),demonstrated a potent inhibitory effect on the intermediate products of HIV-1 reverse transcription(ssDNA and 2LTR),likely acting at the viral entry stage,yet showed no affinity for the PKC-δprotein.These results position compound S11 as a potential candidate for further preclinical investigation and for studies aimed at elucidating the pharmacological mechanism underlying its anti-HIV-1 activity. | HUANG Xiaolei HUANG Xusheng LI Qirun MA Mengdi CUI Yadong YANG Liumeng WANG Haibo LUO Ronghua CHEN Jinglei YANG Jingxuan LIN Jinrong LI Duxin ZHENG Yongtang ZHANG Jian | 2024 | Chinese Journal of Natural Medicines2024，22，4： | 0 |
| 6 | Tumor-targeted metabolic inhibitor prodrug labelled with cyanine dyes enhances immunoprevention of lung cancer显示文摘Recent progress in targeted metabolic therapy of cancer has been limited by the considerable toxicity associated with such drugs.To address this challenge,we developed a smart theranostic prodrug system that combines a fluorophore and an anticancer drug,specifically 6-diazo-5-oxo-L-norleucine(DON),using a thioketal linkage(TK).This system enables imaging,chemotherapy,photodynamic therapy,and on-demand drug release upon radiation exposure.The optimized prodrug,DON-TK-BM3,incorporating cyanine dyes as the fluorophore,displayed potent reactive oxygen species release and efficient tumor cell killing.Unlike the parent drug DON,DON-TK-BM3 exhibited no toxicity toward normal cells.Moreover,DON-TK-BM3 demonstrated high tumor accumulation and reduced side effects,including gastrointestinal toxicity,in mice.This study provides a practical strategy for designing prodrugs of metabolic inhibitors with significant toxicity stemming from their lack of tissue selectivity. | Wen Li Jiali Huang Chen Shen Weiye Jiang Xi Yang Jingxuan Huang Yueqing Gu Zhiyu Li Yi Ma Jinlei Bian | 2024 | Acta Pharmaceutica Sinica B2024，14，2： | 0 |
| 7 | Transforming Chinese Government's Functions Based on Knowledge Economy显示文摘 | Li Ma Jingxuan Han | 2004 | Chinese Business Review2004，3，1： | 0 |
| 8 | Intervalence charge transfer of Cr^(3+)-Cr^(3+) aggregation for NIR-Ⅱ luminescence显示文摘The increasing demand for high-contrast biological imaging,non-destructive testing,and infrared night vision can be addressed by the development of high-performance NIR light-emitting materials.Unlike lanthanide(Ln^(3+))with sharp-line multiplets and isolated Cr^(3+)with NIR-I emission,this study reports the first-ever NIR-Ⅱ broadband luminescence based on the intervalence charge transfer(IVCT)of Cr^(3+)-Cr^(3+)aggregation in gallate magentoplumbite.In particular,LaMgGa11O19:0.7Cr^(3+)exhibits dual-emission(NIR-I,890 nm and NIR-Ⅱ,1200 nm)with a full width at half maximum(FWHM)of 626 nm under 450 nm blue LED excitation.Moreover,this dual-emission exhibits anti-thermal quenching behavior(432%@290 K),attributed to the energy transfer among multiple Cr^(3+)centers.Cryogen absorption spectra,lifetimes decay(2.3 ms),and electron paramagnetic experiments reveal the NIR-Ⅱ luminescence of the Cr^(3+)-Cr^(3+)→Cr^(2+)-Cr^(4+)IVCT transition.The application of LaMgGa_(11)O_(19)∶0.7Cr^(3+)in NIR-Ⅱ biological imaging as an optical contrast agent,non-destructive testing,and night vision is demonstrated.This work provides new insights into broadband NIR-Ⅱ luminescence under UV-NIR excitation based on the IVCT of Cr^(3+)-Cr^(3+)aggregation. | Shengqiang Liu Jingxuan Du Zhen Song Chonggeng Ma Quanlin Liu | 2023 | Light(Science & Applications)2023，12，8： | 0 |
| 9 | Hypoxia-induced reactive oxygen species in organ and tissue fibrosis显示文摘Fibrosis is the end-stage change of damaged tissues in various human diseases,which can lead to permanent scarring or organ malfunction.Hypoxia leads to oxidative stress,mitochondrial dysfunction,and inflammation in dysfunctional organs and tissues.Oxidative stress resulting from the overproduction of reactive oxygen species plays a central role in the fibrosis of injured organs.This review addresses the updated knowledge of the relationship between hypoxia and tissue fibrosis mediated by the reactive oxygen species pathway.Moreover,novel anti-fibrotic strategies are discussed,which may suppress reactive oxygen species and organ fibrosis. | LINSHEN XIE QIAOLAN WANG JINGXUAN MA YE ZENG | 2023 | BIOCELL2023，47，2： | 0 |
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