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| 1 | 抗炎介质表达缺陷参与中性粒细胞型支气管哮喘发病机制:半乳糖凝集素-3和白细胞介素-1RA/白细胞介素-1beta比例显著下降显示文摘支气管哮喘(哮喘)是具有异质性的气道炎症性疾病,其主要特点表现为气道高反应和可变的气流受限。在哮喘的发病机制中,过敏原诱导的TH2淋巴细胞激活以及IL-5介导的嗜酸粒细胞渗出起到重要的作用。近年来发现超过50%的哮喘患者气道的嗜酸粒细胞水平并不增高,并将这种亚型定义为非嗜酸粒细胞型哮喘。其中部分患者表现为气道中性粒细胞明显增高,称为中性粒细胞型哮喘。 | 高鹏 Peter G Gibson Katherine J Baines Ian A Yang John W Upham Paul N Reynolds Sandra Hodge Alan L James Christine Jenkins Matthew J Peters 张捷 Jodie L Simpson | 2016 | 中华结核和呼吸杂志2016，39，11： | 5 |
| 2 | Analysis of 77000 canine uroliths 显示文摘 | Carl A Jody P David J etal | 1999 | Vet Clin Nor Am: Smal Anita Prac1999，29，1： | 1 |
| 3 | A Process to Re- cover Carbon Fibers From Polymer Matric Composites in End- of-Life Vehicles显示文摘 | Jody B J Pomykala J A Daniels E J | 2004 | J Mater2004，56，8： | 1 |
| 4 | Hormone replacement therapy and breast cancer: A qualitative review 显示文摘 | Trody I Manra Whitenmi 1 Jodi A | 2001 | Estrogen Breast Cancer2001，98，3： | 1 |
| 5 | Patient and environmental factors associated with calcium oxalate urolithiasis in dogs 显示文摘 | Chalermpol L Jody P Carl A etal | 2000 | J Am Vet Med Ass2000，217，4： | 1 |
| 6 | AtERF14, a member of the ERF family of transcription factors, plays anonredundant role in plant defense 显示文摘 | Luis onate-Sanchez Jonathan P A Jodi Y | 2007 | Plant Physiology2007，143，1： | 1 |
| 7 | Simplified method for trace analysis of trifluoroacetic acid in plant,soil,and water samples using headspace gas chromatography显示文摘 | Thomas M Cahill Jody A Benesch | | 0，，： | 1 |
| 8 | Recovering CO2 from Large- Size and Medium - Size Stationary Combustors 显示文摘 | A M Wolsky E J Daniels B J Jody | 1991 | Journal of the Air & Waste Management Associa- tion1991，41，4： | 1 |
| 9 | Correlation and accuracy of a wheel force transducer as developed and tested on a flat-tracrtire test system显示文摘 | Jodi I S Richard A M | 2002 | SAE2002，1，： | 1 |
| 10 | Miller, Intelligent Unmanned Air Vehicle Flight Systems 显示文摘 | Jodi A | 2005 | AIAA2005，，： | 1 |
| 11 | AtERF14, a member of the ERF family of transcription factors, plays a nonre- dundant role in plant defense显示文摘 | ONATE-SANCHEZ L Jonathan P A Jodi Y | 2007 | Plant Physiology2007，143，1： | 1 |
| 12 | Nitrate in groundwaters of intensive agricultural areas in coastal Northeastern Australia显示文摘 | Peter J Thorburn Jody S Biggs Keith L Weier Brian A Keating | 2002 | Agriculture Ecosystems and Environment2002，，1： | 1 |
| 13 | Recovering CO2 from large and medium size stationary combustors显示文摘 | Wolsky A M Daniels E J Jody K S | 1991 | Journal of the air and waster management association1991，41，44： | 1 |
| 14 | RNAi in Haemonchus contortus , a potential method for target validation显示文摘 | Jody L Z Paul} A P Els N M etal | 2006 | TRENDS in Parasitology2006，22，11： | 1 |
| 15 | Gonadotropin-releasing hormone (GnRH) analogues and the ovary:Do GnRH antagonists destroy primordial follicles显示文摘 | RUPESH K G JODI A F | 2005 | Fertility and Sterility2005，83，5： | 1 |
| 16 | Redefining the properties of an osmotic agent in an intestinal-specific preservation solution显示文摘AIM: To investigate the effects of dextrans of various molecular weights (Mw) during a 12 h cold storage time-course on energetics, histology and mucosal infiltration of fluorescein isothiocyanate (FITC)-dextran. METHODS: Rodent intestines were isolated and received a standard University of Wisconsin vascular flush followed by intraluminal administration of a nutrientrich preservation solution containing dextrans of varying Mw: Group D1, 73 kdal; Group D2, 276 kdal; Group D3, 534 kdal; Group D4, 1185 kdal; Group D5, 2400 kdal. RESULTS: Using FITC-labeled dextrans, fluorescent micrographs demonstrated varying degrees of mucosal infiltration; lower Mw (groups D1-D3: 73-534 kdal) dextrans penetrated the mucosa as early as 2 h, whereas the largest dextran (D5: 2400 kdal) remained captive within the lumen and exhibited no permeability even after 12 h. After 12 h, median injury grades ranged from 6.5 to 7.5 in groups D1-D4 (73-1185 kdal) representing injury of the regenerative cryptal regions and submucosa; this was in contrast to group D5 (2400 kdal) which exhibited villus denudation (with intact crypts) corresponding to a median injury grade of 4 (P < 0.05). Analysis of tissue energetics reflected a strong positive correlation between Mw and adenosine triphosphate (r 2 = 0.809), total adenylates (r 2 = 0.865) and energy charge (r 2 = 0.667).CONCLUSION: Our data indicate that dextrans of Mw > 2400 kdal act as true impermeant agents during 12 h ischemic storage when incorporated into an intraluminal preservation solution. | Kimberly Schlachter Matthew S Kokotilo Jodi Carter Aducio Thiesen Angela Ochs Rachel G Khadaroo Thomas A Churchill | 2010 | World Journal of Gastroenterology2010，16，45： | 1 |
| 17 | High efficiency DNA extraction from bone by total demineralization显示文摘 | Odile M L Toni M D Jodi A I | 2007 | Forensic Sci Int Genet2007，1，2： | 1 |
| 18 | Thrombophilia and pregnancy complications显示文摘 | Jody I Kujiocich A | 2004 | Am J Ob Gy2004，191，3： | 1 |
| 19 | CO2 Capture from the Flue Cras of Conventional Fossil-Fuel-Fired Power Plants显示文摘 | Wolsky A M Daniels E J Jody B J | 1994 | Environ Prog1994，13，2： | 1 |
| 20 | Hormone replacement therapy and breast cancer:A qualitative review显示文摘 | Trudy L Maura Whiteman Jodi A | 2001 | Estrogen and breast cancer2001，98，3： | 1 |
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