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35篇 您的检索式：作者名="John EJ"

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	题名	作者	年代	出处	被引量
1	Surveying brain tumor heterogeneity by single-cell RNA-sequencing of multi-sector biopsies显示文摘Brain tumors are among the most challenging human tumors for which the mechanisms driving progression and heterogeneity remain poorly understood.We combined single-cell RNA-seq with multi-sector biopsies to sample and analyze single-cell expression profiles of gliomas from 13 Chinese patients.After classifying individual cells;we generated a spatial and temporal landscape of glioma that revealed the patterns of invasion between the different sub-regions of gliomas.We also used single-cell inferred copy number variations and pseudotime trajectories to inform on the crucial branches that dominate tumor progression.The dynamic cell components of the multi-region biopsy analysis allowed us to spatially deconvolute with unprecedented accuracy the transcriptomic features of the core and those of the periphery of glioma at single-cell level.Through this rich and geographically detailed dataset,we were also able to characterize and construct the chemokine and chemokine receptor interactions that exist among different tumor and non-tumor cells.This study provides the first spatial-level analysis of the cellular states that characterize human gliomas.It also presents an initial molecular map of the cross-talks between glioma cells and the surrounding microenvironment with single-cell resolution.	Kai Yu Yuqiong Hu Fan Wu Qiufang Guo Zenghui Qian Waner Hu Jing Chen Kuanyu Wang Xiaoying Fan Xinglong Wu John EJ Rasko Xiaolong Fan Antonio lavarone Tao Jiang Fuchou Tang Xiao-Dong Su	2020	National Science Review2020，7，8：	4
2	Effect of beta(2)-adrenoceptor activation and angiotensin II on tumour necrosis factor and interleukin 6 gene transcription in the rat renal resident maerophage cells 显示文摘	Nakamura A Johns EJ Imaizumi A	1999	Cytokine1999，11，10：	1
3	Chaotic characteristic of renal nerve peak interval sequence in normotensive and hypertensive rats 显示文摘	Zhang T Johns EJ	1998	Clin Exp Pharmacol Physiol1998，25，：	1
4	Effect of hypothermia on baroreflex control of heart rate and renal sympathetic nerve activity in anaesthetized rats显示文摘	Sabharwal R Coote JH Johns EJ	2004	J Physiol2004，557，：	1
5	Role of AngⅡ in mediating somatosensory-ind uced renal nerve-dependent antinatriuresis in the rat显示文摘	Huang CL Johns EJ	1998	Am J Physio1998，275，：	1
6	Serial noninvasive assessment of progressive pulmonary hypertension in a rat model显示文摘	John EJ Lisa M Audrey RM	2002	Am J Physiol Heart Circ Physiol2002，283，：	1
7	Chaotic characteristic of renal nerve peak interval sequence in nomlotensive and hypertensive rats 显示文摘	Zhang Tao Johns EJ	1998	Clin Exp Pharmacol Physiol1998，25，：	1
8	Effect of bate(2)-adrenoceptor activation and angiotensin II on turnout necrosis factor and interleukin 6 gene transcription in the rat renal resident macrophage cells显示文摘	Nakamura A Johns EJ Imaizumi A	1999	Cytokine1999，11，10：	1
9	Effect of β2-adrenoceptor activation and angiotensin Ⅱ on tumour necrosis factor and interleukin 6 gene transcription in the rat renal resident macrophage cells显示文摘	Johns EJ Imaizumi A	1999	Cytokine1999，11，：	1
10	Effect of beta (2) adrenoceptor activation and angiotensin Ⅱ on tumour ne crosis factor and interleukin 6 gene transcription in the rat renal resident macrophage cells显示文摘	Nakamura A Johns EJ Imaizumi A	1999	Cytokine1999，11，：	1
11	The Therapeutic benefit of repeat pereutaneous vertebroplasty at previously treated vertebral levels 显示文摘	John RG Mary EJ Patricia AS	2002	AJNR2002，23，16：	1
12	Relation between Renal Dysfunction and cardiovascular outcomes after myocardial infarction显示文摘	Nageshs A John JV Mcmurray EJ	2004	N Engl J Med2004，351，：	1
13	Effect of beta(2) -adrenoceptor activation and angiotensin Ⅱ on turnout necrosis factor and interleukin 6 gene transcription in the rat renal resident macrophage cells显示文摘	Nakamura A Johns EJ lmaizumi A	1999	Cytokine1999，11，10：	1
14	An investigation into the neural regulation of calcium excretion by the rat kidney显示文摘	Johns EJ Mantius J		0，，：	1
15	Influence of ETR-p1/fl antisense peptide on endothelin-induced constriction in rat renal arcuate arteries显示文摘	Richards NT Johns EJ	1997	Br J Pharm1997，122，2：	1
16	Effect of beta(2)-adrenoceptor activation and angiotensin Ⅱ on tumour necrosis factor and interleukin 6 gene transcription in the rat renal resident macrophage cells显示文摘	Johns EJ Imaizumi A	1999	Cytokine1999，11，10：	1
17	Chaotic characteristic of renal nerve peak interval sequence in normotensive and hypertensive rats 显示文摘	Zhang T Johns EJ	1998	Clin Exp Pharmacol Physiol1998，25，：	1
18	High levels of p66shc and intracellular ROS in permanently arrested early embryos 显示文摘	Favetta LA St John EJ King WA	2007	Free Radical Biology & Medicine2007，42，8：	1
19	Impact of L-NAME on the car- diopulmonary reflex in cardiac hypertrophy显示文摘	Buckley MM Johns EJ	2011	Am J Physiol Regul Integr Comp Physiol2011，301，5：	1
20	Effect of beta(2)-adreno-ceptor activation and angiotensin Ⅱ on tumour necrosis factor and inter- leukin 6 gene transcription in the rat renal resident macrophage cells 显示文摘	Nakamura A Johns EJ Imaizumi A	1999	Cytokine1999，11，10：	1

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