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3篇 您的检索式:作者名="John P Nolan"
    题名 作者 年代 出处 被引量
1Suspension array technology:evolution of the flat-array paradigm显示文摘 NOLAN LARRY A S 2002Trends in Biotechnology2002,20,1:1
2The flow of cytometry into systems biology 显示文摘John P Nolan Loretta Yang 2007Briefings in Functional Genomics and Proteomics2007,6,2:1
3Liver transplantation for hepatocellular carcinoma in Ireland:Pre-operative alpha-fetoprotein predicts tumour recurrence in a 14-year single-centre national experience显示文摘AIM: To examine the results of orthotopic liver transplantation(OLT) for hepatocellular carcinoma(HCC) in Ireland over a 14-year period.METHODS: Cases of HCC receiving OLT between January 1995 and September 2009 in the Irish Liver Transplant Unit were reviewed from a prospectively maintained database. Outcome measures included overall and recurrence free survival, alpha-fetoprotein(AFP) and tumour pathological features. RESULTS: On explant pathology, 57 patients had HCC. The median follow-up time was 42.7 mo. The overall 1, 3 and 5 years survival was 87.7%, 72.1% and 72.4%. There was no difference in survival when comparedto patients undergoing OLT without malignancy. The tumour recurrence rate was 14%. The Milan criteria were exceeded in 32% of cases but this did not predict overall survival or recurrence. On multivariate analysis pre-operative AFP > 100 ng/m L was an independent risk factor for recurrence(RR = 5.2, CI: 1.1-24.3, P = 0.036).CONCLUSION: Patients undergoing OLT for HCC had excellent survival even when conventional listing criteria were exceeded. Pre-operative AFP predicts recurrence independent of tumour size and its role in selection criteria should be investigated in larger studies.Donal B O'Connor John P Burke John Hegarty Aiden P McCormick Niamh Nolan Emir Hoti Donal Maguire Justin Geoghegan Oscar Traynor 2016World Journal of Transplantation2016,6,2:1
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