|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Fatty acid intake in relation to reproductive hormones and testicular volume among young healthy men显示文摘新兴的证据建议饮食的脂肪可以影响阴囊的功能。然而,大多数这域上的出版文学为阴囊的功能把精液质量参数用作唯一的代理。我们在健康的年轻西班牙的人之中与传播繁殖荷尔蒙层次和阴囊的体积检验了胖吸入的协会。这是在在西班牙的 Murcia 区域在 2010 年 10 月和 2011 年 11 月之间进行的 209 个健康男志愿者之中的代表性的研究。参加者在生活方式上完成了问询表,饮食,并且吸烟,并且各经历了物理考试,并且提供了一件血样品。线性回归被用来检验在每种丰满的酸类型和繁殖荷尔蒙层次和阴囊的体积之间的协会。Monounsaturated 丰满的酸吸入相反地与计算免费睾丸激素,全部的睾丸激素,和 inhibin B 的浆液血层次被联系。一个积极协会在多元不堡和的吸入之间被观察丰满的酸,特别地 omega-6 多元不堡和丰满的酸,和 luteinizing 荷尔蒙集中。另外, trans 的吸入丰满的酸与更低的全部的睾丸激素和计算免费睾丸激素集中被联系(P 趋势 = 0.01 和 0.02,分别地) 。omega-3 多元不堡和的吸入丰满的酸断然与阴囊的体积有关当时 omega-6 多元不堡和的吸入丰满的酸和 trans 丰满的酸相反地与阴囊的体积有关。这些数据建议那胖吸入,并且特别地终止 3 的吸入,终止 6,并且 trans 丰满的酸,可以影响阴囊的功能。 | Lidia Minguez-Alarcon Jorge E Chavarro JJaime Mendiola Manuela Roca Cigdem Tanrikut Jesus Vioque Niels Jorgensen Alberto M Torres-Cantero | 2017 | Asian Journal of Andrology2017，19，2： | 5 |
| 2 | Timing, method and discontinuation of hydrocortisone administration for septic shock patients显示文摘AIM To characterize the prescribing patterns for hydrocortisone for patients with septic shock and perform an exploratory analysis in order to identify the variables associated with better outcomes.METHODS This prospective cohort study included 59 patients with septic shock who received stress-dose hydrocortisone.It was performed at 2 critical care units in academic hospitals from June 1st, 2015, to July 31 st, 2016. Demographic data, comorbidities, medical management details, adverse effects related to corticosteroids, and outcomes were collected after the critical care physician indicated initiation of hydrocortisone. Univariate comparison between continuous and bolus administration of hydrocortisone was performed, including multivariate analysis, as well as Kaplan-Meier analysis to compare the proportion of shock reversal at 7 d after presentation. Receiver operating characteristic(ROC) curves determined the best cut-off criteria for initiation of hydrocortisone associated with the highest probability of shock reversal. We addressed the effects of the taper strategy for discontinuation of hydrocortisone, noting risk of shock relapse and adverse effects.RESULTS All-cause 30-d mortality was 42%. Hydrocortisone was administered as a continuous infusion in 54.2% of patients; time to reversal of shock was 49 h longer in patients who were given a bolus administration [59 h(range, 47.5-90.5) vs 108 h(range, 63.2-189); P = 0.001]. The maximal dose of norepinephrine after initiation of hydrocortisone was lower in patients on continuous infusion [0.19 μg/kg per minute(range, 0.11-0.28 μg)] compared with patients who were given bolus [0.34 μg/kg per minute(range, 0.16-0.49); P = 0.004]. Kaplan-Meier analysis revealed a higher proportion of shock reversal at 7 d in patients with continuous infusion compared to those given bolus(83% vs 63%; P = 0.004). There was a good correlation between time to initiation of hydrocortisone and time to reversal of shock(r = 0.80; P < 0.0001); ROC curve analysis revealed that the best criteria for prediction of shock reversal was a time to initiation of hydrocortisone of ≤ 13 h after administration of norepinephrine, with an area under the curve of 0.81(P < 0.001). The maximal dose of norepinephrine at initiation of hydrocortisone with the highest association with shock reversal was ≤ 0.28 μg/kg per minute, with an area under the curve of 0.75(P = 0.0002). On a logistic regression model, hydrocortisone taper was not associated with a lower risk of shock relapse(RR = 1.29; P = 0.17) but was related to a higher probability of hyperglycemia [odds ratio(OR), 5.3; P = 0.04] and hypokalemia(OR = 10.6; P = 0.01). CONCLUSION Continuous infusion of hydrocortisone could hasten the resolution of septic shock compared to bolus administration. Earlier initiation corresponds with a higher probability of shock reversal. Tapering strategy is unnecessary. | Miguel A Ibarra-Estrada Quetzalcóatl Chávez-Pe?a Claudia I Reynoso-Estrella Jorge Rios-Zerme?o Pável E Aguilera-González Miguel A García-Soto Guadalupe Aguirre-Avalos | 2017 | World Journal of Critical Care Medicine2017，6，1： | 4 |
| 3 | 联合钢厂采用无碳排放的ENERGIRON直接还原方案减少温室气体的排放显示文摘在基于高炉冶炼的联合企业中,始终有一些过剩的焦炉煤气、转炉煤气和高炉炉顶煤气,通常这些煤气用于电厂发电。另一种替代方法是使用这些现有的能源气体生产直接还原铁(DRI),将其作为金属化炉料加入高炉,提高粗钢产量,以减少化石燃料单耗。优化利用主要的化石燃料可以显著降低吨钢CO2排放量。采用传统的BF-BOF流程,即使在优化工艺流程的基础上,吨钢CO2排放量也有1.7~1.8t左右。而用产自天然气、焦炉煤气和高炉炉顶煤气的DRI作为金属化炉料加入高炉或电炉,却可显著降低CO2排放量。 | Pablo E Duarte Jorge Becerra 熊林(译) 张友平(校) | 2012 | 世界钢铁2012，12，3： | 3 |
| 4 | Regal Crossing显示文摘 | Charles R Heidengren Jorge E Torrejon Don W Bergman | 2003 | Civil Engineering2003，，7： | 2 |
| 5 | Regression of cardiovascular remodeling in hypertension:Novel relevant mechanisms显示文摘Asymptomatic organ damage due to progressive kidney damage, cardiac hypertrophy and remodeling put hypertensive patients at high risk for developing heart and renal failure, myocardial infarction and stroke. Current antihypertensive treatment normalizes high blood pressure, partially reverses organ damage, and reduces the incidence of heart and renal failure. Activation of the renin-angiotensin system(RAS) is a primary mechanism of progressive organ damage and, specifically, a major cause of both renal and cardiovascular fibrosis. Currently, inhibition of the RAS system [mainly with angiotensin I converting enzyme inhibitors or angiotensin II(Ang II) receptor antagonists] is the most effective antihypertensive strategy for normalizing blood pressure and preventing target organ damage. However, residual organ damage and consequently high risk for cardiovascular events and renal failure still persist. Accordingly, in hypertension, it is relevant to develop new therapeutic perspectives, beyond reducing blood pressure to further prevent/reduce target organ damage by acting on pathways that trigger and maintain cardiovascular and renal remodeling. We review here relevant novel mechanisms of target organ damage in hypertension, their role and evidence in prevention/regression of cardiovascular remodeling and their possible clinical impact as well. Specifically, we focus on the signaling pathway Rho A/Rho kinase, on the impact of the vasodilatory peptides from the RAS and some insights on the role of estrogens and myocardial chymase in cardiovascular hypertensive remodeling. | Jorge E Jalil María P Ocaranza | 2016 | World Journal of Hypertension2016，6，1： | 2 |
| 6 | Cardiovascular physiology in the older adults显示文摘 | Xuming Dai Scott L Hummel Jorge B Salazar George E Taffet Susan Zieman Janice B Schwartz | 2015 | Journal of Geriatric Cardiology2015，12，3： | 2 |
| 7 | Operative Versus Nonoperative Treatment for Stage 0 Distal Rectal Cancer Following Chemoradiation Therapy: Long-term Results显示文摘 | Angelita Habr-Gama Rodrigo Oliva Perez Wladimir Nadalin Jorge Sabbaga Ulysses Ribeiro Afonso Henrique Silva e Sousa Fábio Guilherme Campos Desidério Roberto Kiss Joaquim Gama-Rodrigues | 2004 | Annals of Surgery2004，，4： | 2 |
| 8 | Calligraphic interfaces:towards a new generation of interactive systems显示文摘 | Jorge J Glinert E P | 2000 | Computers & Graphics2000，24，6： | 1 |
| 9 | Novel insight into inhibitor binding of highly symmetric HIV-1 protease显示文摘 | JORG W CHRISTIANE B GERMAN E | 2008 | Chem Bio Chem2008，9，6： | 1 |
| 10 | Major depression following traumatic brain injury显示文摘 | JORGE R E ROBINSON R G MOSER D | 2004 | Arch Gen Psychiatry2004，61，1： | 1 |
| 11 | Collagen network remodelling and diastolic stiffness of the rat left ventricle with pressure overload hypertrophy 显示文摘 | Christian W D Jorge E J Joseph S J | 1988 | Cardiovascular Research1988，22，： | 1 |
| 12 | The Reverse Logistic Process of an Automobile Supply Chain Network Supported by a Collaborative Decision-making Model显示文摘 | JORGE E POLER H R MULA J | 2011 | Group Decis Negot2011，20，6： | 1 |
| 13 | Acomparison of accelerated life testing designs within A singleBayesian inferential framework显示文摘 | J Rene Van Dorp Thomas A Mazzuchi Jorge E Garciduenas | 2006 | Newport Beach UnitedStates2006，，： | 1 |
| 14 | Epstein-Barr virus positive diffuse large B cell lymphoma of the elderly : what we know so far 显示文摘 | Jorge J Brady E | 2011 | Oncologist2011，16，1： | 1 |
| 15 | Male domi- nance, paternity, and relatedness in the Jamaican frut-eat- ing bat ( Artibeus jamaicensis) 显示文摘 | JORGE o JESUS E M GERALD S W | 2003 | Molecular Ecology2003，12，： | 1 |
| 16 | Energy-management system for a hybrid electric vehicle, using ultracapacitors and neural networks显示文摘 | Jorge M Micah E O Juan W D | 2006 | IEEE Transactions on Industrial Electronics2006，，53： | 1 |
| 17 | System dynamics urban sustainability model for Puerto aura in Puebla,Mexico显示文摘 | Jorge A Duran E Alberto P C | 2009 | Systemic Practice and Action Research2009，22，2： | 1 |
| 18 | Hydrolysates of native andmodified soy protein isolates: structural characteristics, solubility andfoaming properties显示文摘 | SARA E MOLINA O JORGE R W | 2002 | Food Research International2002，35，： | 1 |
| 19 | Using soil biomass as an indicator for the biological removal of effluent-derived organic carbon during soil infiltration显示文摘 | Tanja R W Jorg E Drewes J E | 2006 | Water Res2006，40，5： | 1 |
| 20 | Evaluation of approximatem ethods to estimate maximum inelastic displacement demands显示文摘 | MIRANDA E JORGE R G | 2002 | Earthquake Engineering and Structural Dynamics2002，31，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员