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| 1 | Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis. | Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels | 2010 | World Journal of Gastroenterology2010，16，6： | 11 |
| 2 | Silicon and silicon nitride photonic circuits for spectroscopic sensing on-a-chip [Invited]显示文摘There is a rapidly growing demand to use silicon and silicon nitride(Si3N4) integrated photonics for sensing applications, ranging from refractive index to spectroscopic sensing. By making use of advanced CMOS technology,complex miniaturized circuits can be easily realized on a large scale and at a low cost covering visible to mid-IR wavelengths. In this paper we present our recent work on the development of silicon and Si3N4-based photonic integrated circuits for various spectroscopic sensing applications. We report our findings on waveguide-based absorption, and Raman and surface enhanced Raman spectroscopy. Finally we report on-chip spectrometers and on-chip broadband light sources covering very near-IR to mid-IR wavelengths to realize fully integrated spectroscopic systems on a chip. | Ananth Z.Subramanian Eva Ryckeboer Ashim Dhakal Frédéric Peyskens Aditya Malik Bart Kuyken Haolan Zhao Shibnath Pathak Alfonso Ruocco Andreas De Groote Pieter Wuytens Daan Martens Francois Leo Weiqiang Xie Utsav Deepak Dave Muhammad Muneeb Pol Van Dorpe Joris Van Campenhout Wim Bogaerts Peter Bienstman Nicolas Le Thomas Dries Van Thourhout Zeger Hens Gunther Roelkens Roel Baets | 2015 | Photonics Research2015，3，5： | 7 |
| 3 | Effect of hepatic artery embolization on liver hypertrophy response in a rabbit liver VX2tumor model显示文摘BACKGROUND:Portal vein embolization not only induces hypertrophy of the non-embolized liver,but also enhances tumor growth.The latter could be prevented by embolizing the hepatic arteries supplying the tumor-bearing liver segments.This study aimed to determine the effects of transcatheter arterial embolization(TAE)on tumor volume and liver regeneration in a rabbit VX2 tumor model.METHODS:Twenty-three rabbits underwent subcapsular tumor implantation with a VX2 tumor.Two weeks after implantation,18 rabbits were used for TAE experiments,5were for sham controls.Tumor response and liver regeneration response of the embolized cranial and non-embolized caudal liver lobes were assessed by CT volumetry,liver to body weight index,and the amount of proliferating hepatocytes.RESULTS:All super-selective arterial tumor embolization procedures were performed successfully.Despite embolization,the tumor volume increased after an initial steady state.The tumor volume after embolization was smaller than that of the sham group,but this difference was not significant.Massive necrosis of the tumor,however,was seen after embolization,without damage of the surrounding liver parenchyma.There was a significant atrophy response of the tumor bearing cranial lobe after super-selective arterial embolization of the tumor with a concomitant hypertrophy response of the non-embolized,caudal lobe.This regeneration response was confirmed histologically by a significantly higher number of proliferating hepatocytes on the Ki-67 stained slides.CONCLUSIONS:Super-selective,bland arterial coil embolization causes massive necrosis of the tumor,despite increase of volume on CT scan.Atrophy of the tumor bearing liver lobe is seen after arterial embolization of the tumor with a concomitant hypertrophy response of the non-embolized lobe,despite absence of histological damage of the tumor-surrounding liver parenchyma. | Krijn P van Lienden Lisette T Hoekstra Jessica D van Trigt Joris J Roelofs Otto M van Delden Thomas M van Gulik | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，6： | 2 |
| 4 | Spinal mechanisms contribute to analgesia prodused by epidural sufentanil clmbined with bupivacaine far postoperative analgesia显示文摘 | Joris J L Jacob E A Sessler D I | 2003 | Anesth Analg2003，97，： | 1 |
| 5 | Hemodynamic changes induced by laparoscopy and their endocrine correlates: effects of clonidine显示文摘 | JORIS J L CHICHE J D CANIVET J L | 1998 | J Am Coil Cardiol1998，32，5： | 1 |
| 6 | Hem odynam ic changes during laparoscopic cholecystectomy显示文摘 | Joris J L Noirot D P Legrand M J | 1993 | Aneath Analg1993，76，5： | 1 |
| 7 | On the security of to-day* s online electronic banking systems 显示文摘 | JORIS C VALENTIN D DANNY D C | 2002 | Computers & Securi-ty2002，21，3： | 1 |
| 8 | Shrimp white spot virus in the western hemisphere 显示文摘 | Jory D E Dixon H M | 1999 | Aquaculture1999，25，： | 1 |
| 9 | Hybrid Fuzzy Probabilistic Data Association Filter and Joint Probabilistic Data Association Filter 显示文摘 | Mourad O Joris D S | 2002 | Information Sciences2002，142，5： | 1 |
| 10 | 显示文摘 | Yves C Joris V D K Frits C R S | 2002 | Discrete Applied Mathematics2002，123，： | 1 |
| 11 | Oleosin expression and trafficking during oil body biogenesis in tobacco leaf cells显示文摘 | Tony W Jori S Alexander D | 2003 | Genesis2003，35，2： | 1 |
| 12 | Ecotoxicological profile of pyridine 显示文摘 | Jori A Calamari D Cattabeni F | 1983 | Ecotoxicology and Environmental Safety1983，7，： | 1 |
| 13 | Intimate justice: Confronting issues of accountability, respect, and freedom in treatment for abuse and violence 显示文摘 | Jory B Anderson D G-reer C | 1997 | J Marital Fam Ther1997，23，4： | 1 |
| 14 | Effects of intravenous patient -controlled analgesia with morphine,continuous epidural analgesia,and continuous three-in-one block on postoperative pain and knee rehabilitation after unilateral knee arthroplasty显示文摘 | Singelyn F J Deyaert M Joris D | 1998 | Anesth Analg1998，87，： | 1 |
| 15 | Effects of intravenous patient-controlled analgesia with morphine, continuous epi- dural analgesia, and continuous three-in-one block on postop- erative pain and knee rehabilitation after unilateral total knee arthroplasty 显示文摘 | Singelyn FJ Deyaert M Joris D | 1998 | Anesthesia and Analgesia1998，87，： | 1 |
| 16 | Mechanical complications of total shoulder inverted prosthesis 显示文摘 | Deiloye C Joris D Colette A | 2002 | Rev Chir Orthop Reparatrice Appar Mot2002，88，4： | 1 |
| 17 | Compact Mode Converter System for the Cold Test of Assembled Gyrotrons显示文摘 | Jory H Wagner D Blank M | 2001 | Int Journal of Infrared and Millimeter Waves2001，22，10： | 1 |
| 18 | Effects of intravenous pa tient- controlled analgesia with morphine, continuous epidural an- algesia,and continuous three- in- one block on postoperative pain and knee rehabilitation after unilateral total knee arthroplasty显示文摘 | Singelyn FJ Deyaert M Joris D | 1998 | Anesth Analg1998，87，： | 1 |
| 19 | Performance analysis of a priority queue: Expedited Forwarding PHB in DiffServ显示文摘 | Thomas D Joris W Dieter F | 2011 | AEUInternational Journal of Electronics and Communica- tions2011，65，3： | 1 |
| 20 | Role of wild suids in the epidemiology of African swine fever显示文摘 | Jori F Bastos A D | 2009 | Ecohealth2009，6，2： | 1 |
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