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| 1 | Polymorphisms of platelet membrane glycoprotein Iba associated with arterial thrombolic disease显示文摘 | Rocio GC Maria L Jose R | 1998 | Blood1998，92，： | 1 |
| 2 | Polymorphisms of platelet membrane glycoprotein Iba associated with arterial thrombolic disease显示文摘 | Rocio GC Maria L Jose R | 1998 | Blood1998，92，： | 1 |
| 3 | Factors associated with low birth weight in a historical series of deliveries in campinas, Brazil显示文摘 | Pedro RC Jose GC Fernanda GS | 2009 | Rev Assoc Med Bras2009，55，6： | 1 |
| 4 | Factors associated with low birth weight in a historical series of deliveries in campinas, Brazile 显示文摘 | Pedro RC Jose GC Fernanda GS | 2009 | Rev Assoc Med Bras2009，55，6： | 1 |
| 5 | Fusion of multispectral and panchromatic images using improved HIS and PCA mergers based on wavelet decomposition显示文摘 | Maria GA Jose LS Raquel GC | 2004 | IEEE Transactions on Geoseience and Remote Sensing2004，42，6： | 1 |
| 6 | The body mass index, airflow obstruction,dyspnea, and exercise capacity index in chronic obstructive pulmonary disease显示文摘 | Bartolome RC Claudia GC Jose MM | 2004 | N Engl J Med2004，350，10： | 1 |
| 7 | The effectiveness of disease management programmes in reducing hospital re-admission in older patients with heart failure:a systematic review and meta-analysis of published reports显示文摘 | Jonas G Pilar GC Jose RB | 2004 | Eur Heart J2004，25，： | 1 |
| 8 | Citicoline in Vascular Cognitive Impairment and Vascular Dementia After Stroke 显示文摘 | Jose AS Roma GC | 2011 | Stroke2011，25，： | 1 |
| 9 | Comparison of left ventricular volumes and ejection fractions measured by three-dimensional echocardiography versus by two-dimensional echocardiography and cardiac magnetic resonance in patients with various cardiomyopathies显示文摘 | Juan L GC Jose L Z Leopoldo P | 2005 | Am J Cardiol2005，95，： | 1 |
| 10 | Low β-lactamase-negative ampicillin-resistant Haemophilus influezeae strains are best detected by testing amoxicillin susceptibility by the broth mierodilution methodl显示文摘 | Silvia GC Jose C Fedefico R | 2008 | Antimicrobial Agents and Chemotherapy2008，52，7： | 1 |
| 11 | Prospective application of a bleeding and ischemic risks-adjusted antithrombotic protocol in elderly patients revascularized with everolimus-eluting stents:EPIC05-Sierra75 study显示文摘OBJECTIVES Elderly patients show a higher incidence of ischemic and bleeding events after percutaneous transluminal coron-ary intervention(PCI).We sought to investigate outcomes in elderly patients treated with antithrombotic strategy guided by bleeding and ischemic risks after revascularization with last generation everolimus-eluting stent(EES).METHODS Prospective multicenter registry including patients over 75 years revascularized with EES and antithrombotic ther-apy guided by clinical presentation,PCI complexity and PRECISE DAPT score.Co-primary safety endpoints were:(1)composite of cardiac death,myocardial infarction and stent thrombosis and;(2)bleeding(BARC 2-5).Primary efficacy endpoint was target lesion revascularization.A matched group of patients revascularized with current drug-eluting stents and no such tailored antith-rombotic therapy was used as control.RESULTS Finally,1064 patients were included in SIERRA-75 cohort,80.8±4.2 years,36.6%women,71%acute coronary syn-dromes(ACS)and 53.6%complex PCI.Co-primary safety endpoint of major adverse cardiovascular events was met in 6.2%,co-primary safety endpoint of bleeding in 7.8%and primary efficacy endpoint of TKLR in 1.5%.The multivariable adjusted model showed no significant association of the prescribed short/long dual antiplatelet therapy(DAPT)durations with any endpoint suggesting a well tailored therapy.No stent thrombosis reported in the subgroup with 1-3 months DAPT duration.As compared to control group,bleeding BARC 2-5 was significantly lower in SIERRA-75 group(7.4%vs.10.2%,P=0.04)as well as the net safety-efficacy endpoint(14.3%vs.18.5%,P=0.02).CONCLUSIONS In elderly population,the application of this risks-adjusted antithrombotic protocol after revascularization with last generation EES seems to be associated with an improved prognosis in terms of ischemic and bleeding outcomes. | Jose M de la Torre Hernandez Ramon Lopez Palop Jesus M Jimenez Mazuecos Pilar Carrillo Sáez Alejandro Gutierez-Barrios Eduardo Pinar Belen Cid Luis Fernandez Tamara Garcia Camarero Cristóbal Urbano-Carrillo Juan F Oteo Dominguez Victor A Jimenez Diaz Antonio EGomez Menchero Eladio Galindo Fernández Juan GCórdoba Soriano Raymundo Ocaranza Eduardo ArroyoÚcar Koldobika Garcia San Roman Silvio Leal Ginés Martínez Cáceres Jose A Linares Vicente Georgina Fuertes Ferre Xavier Carrillo Juan CRama Merchán Catia Costa Juan Sanchis Renato Fernandes Alberto Rodrigues Jose M Vegas Valle Hélder Pereira Armando Perez de Prado | 2022 | Journal of Geriatric Cardiology2022，19，5： | 0 |
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