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| 1 | 查看详情显示文摘 | Houmard M Berthomé G Joud J C | | 0,,3: | 1 |
| 2 | Low Back Pain: Epidemiology of Consultations 显示文摘 | Joud A Petersson IF Englund M | 2012 | Arthritis Care Res ( Hoboken )2012,64,7: | 1 |
| 3 | Evaluation of the quality of care for severe obstetrical haemorrhage in three French regions 显示文摘 | Bouvier-Colle MH Ould E1 Joud D Vamoux N | 2001 | BJOG2001,108,9: | 1 |
| 4 | Low back pain:epidemiology of consultations显示文摘 | JOUD A PETERSSON I F ENGLUND M | 2012 | Arthritis Care Res (Hoboken)2012,64,7: | 1 |
| 5 | Enhanced cleanability of super-hydrophilic TiO2-SiO2 composite surfaces prepared via a sol-gelroute显示文摘 | Houmard M Berthome G Joud J C | | 0,,3: | 1 |
| 6 | Enhanced cleanability of super-hydrophilic TiO2-SiO2 composite surfaces prepared via a sol-gel route 显示文摘 | Houmard M Berthome G Joud J C Langlet M | 2011 | Surface Science2011,605,34: | 1 |
| 7 | Discussion of A14C3 formation in A1 alloy显示文摘 | Eustathopoulos N and Joud J C | 1974 | Materials Science and Engineering1974,,9: | 1 |
| 8 | Time seriesanalyses for karst river interactions assessment:case of theCoulazou River(Southern France)显示文摘 | COMTE V B JOUDE H ROESCH A | 2008 | Journal of Hydrology2008,349,: | 1 |
| 9 | Discussion of Al4C3 in Al alloy显示文摘 | Eustathopoulos N Joud J C Desre P | 1974 | Materials Science and Engineering1974,9,: | 1 |
| 10 | The Effect of Ageing on Passive Films Formed on Stainless Steels Annealing in Hydrogen Atmospheres 显示文摘 | Gorse D Joud J C | 1992 | Corrosion Science1992,33,9: | 1 |
| 11 | The wetting of carbon by aluminium and aluminium alloys显示文摘 | N. Eustathopoulos J. C. Joud P. Desre J. M. Hicter | 1974 | Journal of Materials Science1974,,8: | 1 |
| 12 | The wetting of carbon by aluminium and aluminium alloys显示文摘 | EUSTATHOPOULOS N JOUD J C DESRE P | 1974 | Journal of Materials Science1974,,9: | 1 |
| 13 | Prevalence and in- cidence of rheumatoid arthritis in southern Sweden 2008 and their relation to prescribed biologies显示文摘 | Eng|und M Joud A Geborek P | 2010 | Rheumatolo- gy2010,49,8: | 1 |
| 14 | Prevalence and in- cidence of rheumatoid arthritis in southern Sweden 2008 and their relation to prescribed biologies显示文摘 | Eng|und M Joud A Geborek P | 2010 | Rheumatolo- gy2010,49,8: | 1 |
| 15 | The wetting of carbon by aluminum and aluminum alloys 显示文摘 | EUSTATHOPOULOS N JOUD J C DESRE P | 1974 | Journal of Materials Science1974,9,: | 1 |
| 16 | Evaluation of the quality of care for severe obstetrical haemorrhage in three French regions显示文摘 | Bouvier-Colle MH Ould E1 Joud D Varnoux N | 2001 | BJOG2001,108,9: | 1 |
| 17 | Layered Hybrid ARQ/FEC for Increasing Quality of Service for MPEG 1-2 Video Communication over networks显示文摘 | Abdel Messie Joud | 2003 | Design and Practical Implementation Masters Abstracts International2003,41,6: | 1 |
| 18 | The metabolite, alpha-ketoglutarate inhibits non-alcoholic fatty liver disease progression by targeting lipid metabolism显示文摘Background:Non-alcoholic liver disease is of increased concern and contributing to economic burdens not only in developing countries but in developed countries as well.Identifying the biomarker of early diagnosis and early intervention approaches for non-alcoholic liver disease is unmet and required further investigation.Although the alpha-ketoglutarate(a-KG)is recently proposed to be a potential biomarker in differentiating patients with obesity from those with non-alcoholic liver disease,how a-ketoglutatate is involved in the fatty liver progression is not clear.Methods:A high-fat diet(HFD)feeding animal model,liver functional assays,and molecular approaches were adopted to clarify the impact of a-KG in fatty liver progression.Results:In the current study,it was found that dietary a-KG would inhibit weight gain in male and female mice fed with a normal chew or HFD.HFD feeding caused fatty liver in male mice,but a-KG treatment could substantially inhibit hepatic steatosis progression.Biochemical studies revealed the possible linkage of a-KG protective functions to lipid metabolism.Further analysis identified the important role of peroxisome proliferator-activated receptors in beneficial a-KG-mediated effects on fatty liver progression.Conclusions:The current study demonstrates the therapeutic potential of a-KG and how it may be used,via dietary supplementation,as a preventive intervention for non-alcoholic liver disease in obese patients. | Katsuya Nagaoka Joud Mulla Kevin Cao Zhixiang Cheng Dan Liu William Mueller Amalia Bay Grace Hildebrand Shaolei Lu Chiung-Kuei Huang | 2020 | Liver Research2020,4,2: | 0 |
| 19 | Human mesenchymal stem cells exhibit altered mitochondrial dynamics and poor survival in high glucose microenvironment显示文摘BACKGROUND Mesenchymal stem cells(MSCs)are a type of stem cells that possess relevant regenerative abilities and can be used to treat many chronic diseases.Diabetes mellitus(DM)is a frequently diagnosed chronic disease characterized by hyperglycemia which initiates many multisystem complications in the long-run.DM patients can benefit from MSCs transplantation to curb down the pathological consequences associated with hyperglycemia persistence and restore the function of damaged tissues.MSCs therapeutic outcomes are found to last for short period of time and ultimately these regenerative cells are eradicated and died in DM disease model.AIM To investigate the impact of high glucose or hyperglycemia on the cellular and molecular characteristics of MSCs.METHODS Human adipose tissue-derived MSCs(hAD-MSCs)were seeded in low(5.6 mmol/L of glucose)and high glucose(25 mmol/L of glucose)for 7 d.Cytotoxicity,viability,mitochondrial dynamics,and apoptosis were deplored using specific kits.Western blotting was performed to measure the protein expression of phosphatidylinositol 3-kinase(PI3K),TSC1,and mammalian target of rapamycin(mTOR)in these cells.RESULTS hAD-MSCs cultured in high glucose for 7 d demonstrated marked decrease in their viability,as shown by a significant increase in lactate dehydrogenase(P<0.01)and a significant decrease in Trypan blue(P<0.05)in these cells compared to low glucose control.Mitochondrial membrane potential,indicated by tetramethylrhodamine ethyl ester(TMRE)fluorescence intensity,and nicotinamide adenine dinucleotide(NAD+)/NADH ratio were significantly dropped(P<0.05 for TMRE and P<0.01 for NAD+/NADH)in high glucose exposed hAD-MSCs,indicating disturbed mitochondrial function.PI3K protein expression significantly decreased in high glucose culture MSCs(P<0.05 compared to low glucose)and it was coupled with significant upregulation in TSC1(P<0.05)and downregulation in mTOR protein expression(P<0.05).Mitochondrial complexes I,IV,and V were downregulated profoundly in high glucose(P<0.05 compared to low glucose).Apoptosis was induced as a result of mitochondrial impairment and explained the poor survival of MSCs in high glucose.CONCLUSION High glucose impaired the mitochondrial dynamics and regulatory proteins in hAD-MSCs ensuing their poor survival and high apoptosis rate in hyperglycemic microenvironment. | Ejlal Abu-El-Rub Fatimah Almahasneh Ramada R Khasawneh Ayman Alzu'bi Doaa Ghorab Rawan Almazari Huthaifa Magableh Ahmad Sanajleh Haitham Shlool Mohammad Mazari Noor S Bader Joud Al-Momani | 2023 | World Journal of Stem Cells2023,15,12: | 0 |
| 20 | Continuous Mobile User Authentication Using a Hybrid CNN-Bi-LSTM Approach显示文摘Internet of Things (IoT) devices incorporate a large amount ofdata in several fields, including those of medicine, business, and engineering.User authentication is paramount in the IoT era to assure connecteddevices’ security. However, traditional authentication methods and conventionalbiometrics-based authentication approaches such as face recognition,fingerprints, and password are vulnerable to various attacks, including smudgeattacks, heat attacks, and shoulder surfing attacks. Behavioral biometrics isintroduced by the powerful sensing capabilities of IoT devices such as smartwearables and smartphones, enabling continuous authentication. ArtificialIntelligence (AI)-based approaches introduce a bright future in refining largeamounts of homogeneous biometric data to provide innovative user authenticationsolutions. This paper presents a new continuous passive authenticationapproach capable of learning the signatures of IoT users utilizing smartphonesensors such as a gyroscope, magnetometer, and accelerometer to recognizeusers by their physical activities. This approach integrates the convolutionalneural network (CNN) and recurrent neural network (RNN) models to learnsignatures of human activities from different users. A series of experiments areconducted using the MotionSense dataset to validate the effectiveness of theproposed method. Our technique offers a competitive verification accuracyequal to 98.4%.We compared the proposed method with several conventionalmachine learning and CNN models and found that our proposed modelachieves higher identification accuracy than the recently developed verificationsystems. The high accuracy achieved by the proposed method proves itseffectiveness in recognizing IoT users passively through their physical activitypatterns. | Sarah Alzahrani Joud Alderaan Dalya Alatawi Bandar Alotaibi | 2023 | Computers, Materials & Continua2023,,4: | 0 |