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| 1 | 内侧固定平台单髁置换术后的冠状面下肢力线是翻修的影响因素显示文摘膝关节单髁置换术(unicompartmental knee arthroplasty,UKA)后患者冠状面的下肢力线被认为是影响手术长期疗效的一个重要因素,但关于最佳的UKA术后下肢力线还没有形成明确共识。一些研究主张术后下肢力线应保持在中立位,而另一些研究认为即使术后下肢力线存在10°的内翻也可获得良好的临床效果。 | Sean E Slaven John P Cody Robert A Sershon Henry Ho Robert H Hopper Jr Kevin B Fricka 李亚坤(整理) 张民(整理) | 2020 | 实用骨科杂志2020，26，12： | 15 |
| 2 | Mycophenolate mofetil for drug-induced vanishing bile duct syndrome显示文摘Amoxicillin/clavulanate is associated with liver injury, mostly of a cholestatic pattern. While outcomes are usually benign, progression to cirrhosis and death has been reported. The role of immunosuppressive therapy for patients with a protracted course is unclear. We report the case of an elderly patient who developed prolonged cholestasis secondary to amoxicillin/clavulanate. Vanishing bile duct syndrome was confirmed by sequential liver biopsies. The patient responded to prednisone treatment, but could not be weaned off corticosteroids, even when azathioprine was added. Complete withdrawal of both prednisone and azathioprine was possible by using mycophenolate mofetil, an inosine monophosphate dehydrogenase inhibitor. Sustained remission has been maintained for more than 3 years with low-dose mycophenolate mofetil. | S Simona Jakab A Brian West Dennis M Meighan Robert S Brown Jr William B Hale | 2007 | World Journal of Gastroenterology2007，13，45： | 8 |
| 3 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 4 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 5 | 金龟子绿僵菌分生孢子暴露在B段紫外光下毒力的降低显示文摘The UV-A and UV-B wavelengths of solar radiation may seriously reduce viability of Metarhizium anisopliae conidia,a fungus used extensively in Brazil for insect pest control.The conidial tolerances to UV-A and UV-B radiation were studied for one isolate(IBCB 425) commercially available product produced on rice grains.Aqueous or oil emulsion conidial suspensions were irradiated for 0(control),2,or 3 h using the solar simulator filtered with diacetate filter to remove UV-C radiation which afforded 652 mW·m-2 in the spectral range of 280~370 nm.The UV tolerance was based on conidial germination(viability) and virulence to Diatraea saccharalis larvae.Conidia formulated with oil emulsion had higher survival after 3 h of UV exposure,but the virulence of the conidia previously exposed to 2 h of UV radiation were similar when oil formulated or not.The mortality of D.saccharalis caterpillars exposed to non-UV-irradiated conidia was greater than that of larvae exposed to irradiated conidia,and the LT50 values were lower for the non-irradiated suspensions than for those irradiated.This apparent reduction in virulence was directly related reduction in viability or delay of germination of UV-irradiated conidia. | Edimara A Francisco Drauzio E N Rangel Newton La Scala Jr José C Barbosa Antnia do C B Correia | 2008 | 安徽农业大学学报2008，35，2： | 2 |
| 6 | 遗传性肥胖与心房颤动的关系显示文摘观察性研究已经确定了体质量指数(body mass index,BMI)与心房颤动之间的关联。然而,从观察性研究中推断因果关系会受到混杂因素、逆因果关系和偏倚的影响。该研究的主要目的是应用BMI的遗传学预测因子评估BMI与心房颤动之间的因果关系。方法:纳入1987-2002年期间在美国、冰岛和荷兰实施的7个前瞻性人群队列研究中基线无心房颤动的欧洲血统个体51 646人, | 刘莉 叶鹏 Chatterjee NA Giulianini F Geelhoed B Lunetta KL Misialek JR Niemeijer MN Rienstra M Rose LM Smith AV Arking DE Ellinor PT Heeringa J Lin H Lubitz SA Soliman EZ Verweij N Alonso A Benjamin EJ Gudnason V Stricker BH van der Harst P Chasman DI Albert CM | 2017 | 中华高血压杂志2017，25，2： | 2 |
| 7 | D-MELD risk capping improves post-transplant and overall mortality under markov microsimulation显示文摘AIM: To hypothesize that the product of calculated Model for End-Stage Liver Disease score excluding exception points and donor age(D-MELD) risk capping ± Rule 14 could improve post liver transplant and overall survival after listing.METHODS: Probabilities derived from the United Network for Organ Sharing database between 2002 and 2004 were used to simulate potential outcomes for all patients listed for transplantation. The Markov simula-tion was then modified by screening matches using a 1200 or 1600 D-MELD risk cap ± allowing transplants for Model for End-Stage Liver Disease(MELD) ≤ 14(Rule 14). The differential impact of the rule changes was assessed.RESULTS: The Markov simulation accurately reproduced overall and post transplant survival. A 1200 D-MELD risk cap improved post-transplant survival. Both the 1200 and 1600 risk caps improved overall survival for waitlisted patients. The addition of Rule 14 further improved post transplant and overall survival by redistribution of donor livers to recipients in higher MELD subgroups. The mechanism for improved overall and post-transplant survival after listing was due to shifting a larger percentage of transplants to the moderate MELD score subgroup(MELD 15-29) while also ensuring that high MELD recipients have livers of high quality to achieve excellent post transplant survival.CONCLUSION: A 1200 D-MELD risk cap + Rule 14 provided the greatest overall benefit primarily by focusing liver transplantation towards the moderate MELD recipient. | Jeffrey B Halldorson Robert L Carithers Jr Renuka Bhattacharya Ramasamy Bakthavatsalam Iris W Liou Andre A Dick Jorge D Reyes James D Perkins | 2014 | World Journal of Transplantation2014，4，3： | 2 |
| 8 | Purification,characterization,and cDNA structure of isoamylase from developing endosperm of rice显示文摘 | Kubo A Francisco P B Jr Nakakita M Harada K Minaka N Nakamura Y | 1999 | Planta1999，208，2： | 1 |
| 9 | Effect of Copper Content and Heat Treatment on the Stress Corrosion Characteristics of Al-6Zn- 2Mg-XCu Alloys显示文摘 | Sarkar B Marek M Starke E A Jr | 1981 | Metallurgical TransactionsA1981，12，11： | 1 |
| 10 | Transforming growth factor-betal modulates extracellular matrix production, proliferation, and apoptosis of endothelial progenitor cells in tissue-engineering scaffolds显示文摘 | Sales V L Engelmayr G C Jr Mettler B A | 2006 | Circulation2006，，： | 1 |
| 11 | Surgical treatment of trigeminal neuralgia ;comparison of microvascular decompression, percutaneous ablation, and stereotactic radiosurgery 显示文摘 | Cowan A Jr Brahma B | 2003 | Neurosurgery2003，8，3： | 1 |
| 12 | Gene expression analysis during liver stage development of Plasmodium 显示文摘 | SACCI J B Jr AZAD A F | 2002 | Int J Parasitol2002，32，13： | 1 |
| 13 | Magnetic resonance imaging of cavernous sinus invasion by pituitary adenoma diagnostic criteria and surgical findings 显示文摘 | VIEIRA J O JR CUKIERT A LIBERMAN B | 2004 | Arq Neuropsiquiatr2004，62，2： | 1 |
| 14 | Induced side forces at high angles of attack显示文摘 | WARDLAW A B Jr and MORRISON A M | 1976 | Journal of Spacecraft1976，13，10： | 1 |
| 15 | The cor- relation of the magnetic properties and the magnetocaloric effect in ( Gd1-x Erx ) NiAl alloys 显示文摘 | Korte B J Pecharsky V K Gschueidner Jr K A | 1998 | J Appl Phys1998，84，： | 1 |
| 16 | Spatially distri- buted control network for flow proportional chemical in- jection with center pivot sprinkler irrigation显示文摘 | King B A Wall R W Taberna J P Jr | 2009 | Applied Engineering in Agriculture2009，25，5： | 1 |
| 17 | Molecular epi-demiology and evolution of enterovirus 71 strains isolated from 1970 to 1998显示文摘 | Brown B A Oberste M S Alexander J P Jr | | 0，，： | 1 |
| 18 | Introduction to a system for distributed databases (SDD-1)显示文摘 | Rothnie Jr J B Bernstein P A Fox S | 1980 | ACM Transactions on Database Systems (TODS)1980，5，1： | 1 |
| 19 | To treat or not to treat? A meta-analysis of the use of cholinesterase inhibitors in mild cognitive impairment for delaying progression to Alzheimer's disease显示文摘 | Diniz B S Pinto J A Jr Gonzaga M L | 2009 | Eur Arch Psychiatry Clin Neurosci2009，259，： | 1 |
| 20 | Magnetic resonance imaging of cavernous sinus invasion by pituitary adenoma diagnostic criteria and surgical findings 显示文摘 | VIEIRA J O Jr CUKIERT A LIBERMAN B | 2004 | ArqNeuropsiquiatr2004，62，2： | 1 |
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