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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Expression of cell cycle control proteins in primary colorectal tumors does not always predict expression in lymph node metastases显示文摘 | McKay Joy J Douglas Val G | 2000 | Clin Cancer Res2000，6，3： | 1 |
| 3 | Highly Coupon and Sales Prone Consumers : Benefits beyond Price Savings 显示文摘 | Judith A G Burton S | 2003 | Journal of Advertising Research''2003，43，2： | 1 |
| 4 | Using the Credit Spread as an Option-Risk Factor: Size and Value Effects in CAPM 显示文摘 | HWANG Y S MIN H G JUDITH A | 2010 | Journal of Banking and Finance2010，34，9： | 1 |
| 5 | Impact of thrombolysis, intra-aortic balloon pump counterpulsation, and their combination in cardiogenic shock complicating acute myocardial infarction: a report from the SHOCK Trial Registry显示文摘 | Timothy A Sanborn Lynn A Sleeper Eric R Bates Alice K Jacobs Jean Boland John K French Jo Dens Vladimir Dzavik Sebastian T Palmeri John G Webb Mark Goldberger Judith S Hochman | 2000 | Journal of the American College of Cardiology2000，，： | 1 |
| 6 | Markers for Host - Induced Gene Expression in Trichophyton Dermatophytosis 显示文摘 | KAUFMAN G BERDICEVSKY I JUDITH A | 2005 | Infect Immune2005，73，10： | 1 |
| 7 | Discrete event fuzzy airport control显示文摘 | John R C Philip D C Judith A G | 1992 | IEEE Transactions on Systems Man and Cybernetics1992，22，2： | 1 |
| 8 | Self-care self-efficacy,quality of life,and depression after stroke显示文摘 | Robinson G Johnston V Judith A | 2000 | Arch Phys Med Rehabil2000，81，4： | 1 |
| 9 | The Strategic ImplementationProcess Evoking Strategic Consensus through Communication显示文摘 | Molly I R Anne V Judith A G | 2002 | Journal of Business Research2002，55，4： | 1 |
| 10 | The interferon antagonistic activities of the V proteins from two strains Newcastle disease vi- rus correlate with their known virulence properties 显示文摘 | Judith G A Subbiah E Siba K S | 2010 | Virus Research2010，147，： | 1 |
| 11 | In vivo detection of porcine reproductive and respiratory syndrome virus RNA by in situ hybridization at different times postinfection 显示文摘 | JUNG H S VICKIE L C JUDITH A G | 1996 | J Clin Microbio11996，34，9： | 1 |
| 12 | Assess- ing the relationships between contextual factors and re- search utilization in nursing: Systematic literature re- view显示文摘 | Judith M M Janssen M A Cummings G G | 2006 | J Adv Nurs2006，55，5： | 1 |
| 13 | Gelling properties of kefiran,a food-grade polysaceharide obtained from kefir grain显示文摘 | Judith A Mariano L Analia G | | 0，，03： | 1 |
| 14 | Propulsion drive models for full electric marine propulsion systems 显示文摘 | Judith M A Aurelio G V Mike B | 2009 | IEEE Transactions on Industry Applications2009，45，2： | 1 |
| 15 | Antifouling Activity of Symbiotic Bacteria from Sponge Aplysina Gerardogreeni 显示文摘 | Ruth Noeml A R Claudia Judith H G Birbara G A | 2014 | International Biodeterioration & Biodegradation2014，，90： | 1 |
| 16 | Investigating Sponsorship Effeetiveness: Do Less Familiar Brands Have an Advantage over more Familiar Brands in Single and Multiple Sponsorship Arrangement显示文摘 | STACY L G JUDITH A G F | 2005 | Journal of Brand Management2005，13，1： | 1 |
| 17 | Consumer evaluation and quality measurement of fresh-cut slices of Fuji,'Golden Delicious,'GoldRush,and 'Granny Smith' apples显示文摘 | Judith A A Robert A S Kenneth C G | 2004 | Postharvest Biol Tec2004，33，2： | 1 |
| 18 | Cause-related Marketing (CRM) 显示文摘 | STACY L G JUDITH A G F | 2007 | Journal of Advertising2007，36，4： | 1 |
| 19 | Consumer evaluation and quality measurement of fresh-cut slices of 'Fuji', 'Golden Delicious', 'GoldRush' and 'Granny Smith' apples显示文摘 | Judith A A Robert A S Kennth C G | 2004 | Postharvest Biology and Technology2004，33，： | 1 |
| 20 | Molecular basis for a link between complement and the vascular complications of diabetes显示文摘 | Juan A Judith H Rudolf Nicole K Allison G Luis A | 2000 | PNAS2000，97，10： | 1 |
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