|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Identification of serum proteins discriminating colorectal cancer patients and healthy controls using surface-enhanced laser desorption ionisation-time of flight mass spectrometry显示文摘瞄准:为颜色检测新浆液简历标记由浆液蛋白质与提高表面的激光解吸附作用 ionisation 介绍的表面的癌症(CRC )-- 飞行团分光术(SELDI-TOF MS ) 的时间。方法:二个独立浆液样品集合与 ProteinChip 技术独立被分析(集合 A:40 CRC+49 健康控制;集合 B:37 CRC+31 健康控制) ,有一个弱阳离子的使用的芯片交换一半和缓冲区 pH 5。差别的歧视的力量表示了蛋白质与一个分类树算法被估计。产生分类树的敏感和特性被盲目地从集合 B 并且反过来也如此从集合 A 把数据用于产生的树获得。CRC 浆液蛋白质侧面也与从胸的那些相比,卵巢,前列腺,和非小的房间肺癌症。结果:Mass-to-charge 比率(m/z ) 3.1x10 (3 ) , 3.3x10 (3 ) , 4.5x10 (3 ) , 6.6x10 (3 ) 和 28x10 (3 ) 在最好执行的分类树上被用作分类器。树敏感和特性在 65% 和 90% 之间。大多数这些歧视的 m/z 价值在调查的另外的瘤类型也是不同的。M/z 3.3x10 (3 ) ,在大多数树上的主要分类器,是 6.6x10 (3 ) 的一种二倍地控告的形式 -Da 蛋白质。后者作为 apolipoprotein C-I 被识别。M/z 3.1x10 (3 ) 作为 apolipoprotein A-I 作为白朊,和 m/z 28x10 (3 ) 的 N 终端碎片被识别。结论:分类树模式分析跟随的 SELDI-TOF MS 是为为 CRC 发现新浆液标记的一种合适的技术。Biomarkers 能与高敏感和特性在独立样品集合被识别并且 reproducibly 检测了。尽管为 CRC 不特定,这些简历标记在监视的疾病和治疗有一个潜在的角色。 | Judith YMN Engwegen Helgi H Helgason Annemieke Cats Nathan Harris Johannes MG Bonfrer Jan HM Schellens Jos H Beijnen | 2006 | World Journal of Gastroenterology2006，12，10： | 45 |
| 2 | Autophagy in filamentous fungi显示文摘 | Judith K. Pollack Steven D. Harris Mark R. Marten | 2008 | Fungal Genetics and Biology2008，，1： | 1 |
| 3 | Molecular forms of prostate-specific antigen and the human kallikrein gene family: A new era显示文摘 | Robert T. McCormack T.J. Wang Harry G. Rittenhouse Robert L. Wolfert Judith A. Finlay Hans Lilja Roger L. Okoloff Joseph E. Oesterling | 1995 | Urology1995，，5： | 1 |
| 4 | Molecular forms of prostate-specific antigen and the human kallikrein gene family: A new era显示文摘 | Robert T. McCormack T.J. Wang Harry G. Rittenhouse Robert L. Wolfert Judith A. Finlay Hans Lilja Roger L. Okoloff Joseph E. Oesterling | 1995 | Urology1995，，5： | 1 |
| 5 | Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group I: Epidemiology显示文摘 | Barbara V. Howard Beatriz L. Rodriguez Peter H. Bennett Maureen I. Harris Richard Hamman Lewis H. Kuller Thomas A. Pearson Judith Wylie-Rosett | 2002 | Circulation: Journal of the American Heart Association2002，，18： | 1 |
| 6 | TOLERANCE INDUCTION BY 'MEGADOSE' HEMATOPOIETIC TRANSPLANTS: Donor-Type Human CD34 Stem Cells Induce Potent Specific Reduction of Host Anti-Donor Cytotoxic T Lymphocyte Precursors in Mixed Lymphocyte Culture1显示文摘 | Nurit Rachamim Judith Gan Harry Segall Rita Krauthgamer Hadar Marcus Alain Berrebi Massimo Martelli Yair Reisner | 1998 | Transplantation1998，，10： | 1 |
| 7 | Animal antibiotic use has an early but important impact on the emergence of antibiotic resistance in human commensal bacteria 显示文摘 | David L Smith Anthony D Harris Judith A Johnson | 2002 | Proc Natl Acad Sci2002，99，9： | 1 |
| 8 | Techers' Technological Pedagogical Content Knowledge and Learning Activity Types : Curriculum-based Technology Integration Reframed显示文摘 | Judith Harris Punya Mishr a and Matthew Koehler | 2009 | Journal of Research on Technology in Education2009，，4： | 1 |
| 9 | Molecular forms of prostate-specific antigen and the human kallikrein gene family: A new era显示文摘 | Robert T. McCormack T.J. Wang Harry G. Rittenhouse Robert L. Wolfert Judith A. Finlay Hans Lilja Roger L. Okoloff Joseph E. Oesterling | 1995 | Urology1995，，5： | 1 |
| 10 | Where is the child’s environment?A group socialization theory of development显示文摘 | Harris Judith Rich | 1995 | Psychological Review1995，102，3： | 1 |
| 11 | Technological Ped agogical Content Knowledge (TPACK) in Action: A De scriptive Study of Secondary Teachers' Curriculum-Base d, Technology-Related Instructional Planning 显示文摘 | Harris Judith B & Hofer Mark J | 2011 | Journal of Research on Technology in Education2011，43，3： | 1 |
| 12 | Where is the Child's Envrionment? A Group Socialization Theory of Development显示文摘 | Judith Rich Harris | 1995 | Middletown Newjersy : the American Psychological Review1995，，3： | 1 |
| 13 | Effect of force direction on femoral francture load for two types of loading conditions显示文摘 | Joyce H K Harry B S Judith A F | 2001 | Journal of Orthopaedic Research2001，19，： | 1 |
| 14 | GM-1 ganglioside administration combined with physical therapy restores ambulation in humans with chronic spinal cord injury显示文摘 | Judith B Walker Michelle Harris | | 0，，02： | 1 |
| 15 | B-cell Lymphomas With Concurrent IGH-BCL2 and MYC Rearrangements Are Aggressive Neoplasms With Clinical and Pathologic Features Distinct From Burkitt Lymphoma and Diffuse Large B-cell Lymphoma显示文摘 | Matija Snuderl Olga K. Kolman Yi-Bin Chen Jessie J. Hsu Adam M. Ackerman Paola Dal Cin Judith A. Ferry Nancy Lee Harris Robert P. Hasserjian Lawrence R. Zukerberg Jeremy S. Abramson Ephraim P. Hochberg Hang Lee Alfred I. Lee Christiana E. Toomey Aliyah R. | 2010 | The American Journal of Surgical Pathology2010，，3： | 1 |
| 16 | Long-term effects of fire frequency and season on herbaceous vegetation in savannas of the Kruger National Park,South Africa显示文摘Aims:The long-term effects of changing fire regimes on the herbaceous component of savannas are poorly understood but essential for understanding savanna dynamics.We present results from one of the longest running(>44 years)fire experiments in savannas,the experimental burn plots(EBPs),which is located in the Kruger National Park(South Africa)and encompasses four major savanna vegetation types that span broad spatial gradients of rainfall(450–700 mm)and soil fertility.Methods:Herbaceous vegetation was sampled twice in the EBPs using a modified step-point method,once prior to initiation of the experiment(1954)and again after 44–47 years.Different combinations of three fire frequency(1-,2-and 3-year return intervals)and five season(before the first spring rains,after the first spring rains,mid-summer,late summer and autumn)treatments,as well as a fire exclusion treatment,were applied at the plot level(;7 ha each),with each treatment(n=12 total)replicated four times at each of the four sites(n=192 plots total).The effects of long-term alterations to the fire regime on grass community structure and composition were analyzed separately for each site.Important Findings:Over the 44+years duration of the experiment,fires were consistently more intense on sites with higher mean annual rainfall(>570 mm),whereas fires were not as intense or consistent for sites with lower and more variable rainfall(<510 mm)and potentially higher herbivory due to greater soil fertility.Because the plots were open to grazing,the impacts of herbivory along with more variable rainfall regimes likely minimized the effects of fire for the more arid sites.As a consequence,fire effects on grass community structure and composition were most marked for the higher rainfall sites and generally not significant for the more arid sites.For the high-rainfall sites,frequent dry season fires(1-to 3-year return intervals)resulted in high grass richness,evenness and diversity,whereas fire exclusion and growing season fires had the lowest of these measures and diverged the most in composition as the result of increased abundance of a few key grasses.Overall,the long-term cumulative impacts of altered fire regimes varied across broad climatic and fertility gradients,with fire effects on the grass community decreasing in importance and herbivory and climatic variability likely having a greater influence on community structure and composition with increasing aridity and soil fertility. | Melinda D.Smith Brian Wvan Wilgen Catherine E.Burns Navashni Govender Andre L.F.Potgieter Sandy Andelman Harry C.Biggs Judith Botha Winston S.W.Trollope | 2013 | Journal of Plant Ecology2013，6，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员