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| 1 | Facile metagrating holograms with broadband and extreme angle tolerance显示文摘The emerging meta-holograms rely on arrays of intractable meta-atoms with various geometries and sizes for customized phase profiles that can precisely modulate the phase of a wavefront at an optimal incident angle for given wavelengths.The stringent and band-limited angle tolerance remains a fundamental obstacle for their practical application,in addition to high fabrication precision demands.Utilizing a different design principle,we determined that facile metagrating holograms based on extraordinary optical diffraction can allow the molding of arbitrary wavefronts with extreme angle tolerances(near-grazing incidence)in the visible–near-infrared regime.By modulating the displacements between uniformly sized meta-atoms rather than the geometrical parameters,the metagratings produce a robust detour phase profile that is irrespective of the wavelength or incident angle.The demonstration of high-fidelity meta-holograms and in-site polarization multiplexing significantly simplifies the metasurface design and lowers the fabrication demand,thereby opening new routes for flat optics with high performances and improved practicality. | Zi-Lan Deng Junhong Deng Xin Zhuang Shuai Wang Tan Shi Guo Ping Wang Yao Wang Jian Xu Yaoyu Cao Xiaolei Wang Xing Cheng Guixin Li Xiangping Li | 2018 | Light(Science & Applications)2018，7，1： | 17 |
| 2 | Spatial distribution and ecological risk assessment of heavy metals in surface sediments from a typical plateau lake wetland, China显示文摘 | Junhong Bai Baoshan Cui Bin Chen Kejiang Zhang Wei Deng Haifeng Gao Rong Xiao | 2009 | Ecological Modelling2009，，2： | 3 |
| 3 | Phyllotaxis-inspired nanosieves with multiplexed orbital angular momentum显示文摘Nanophotonic platforms such as metasurfaces,achieving arbitrary phase profiles within ultrathin thickness,emerge as miniaturized,ultracompact and kaleidoscopic optical vortex generators.However,it is often required to segment or interleave independent sub-array metasurfaces to multiplex optical vortices in a single nano-device,which in turn affects the device’s compactness and channel capacity.Here,inspired by phyllotaxis patterns in pine cones and sunflowers,we theoretically prove and experimentally report that multiple optical vortices can be produced in a single compact phyllotaxis nanosieve,both in free space and on a chip,where one meta-atom may contribute to many vortices simultaneously.The time-resolved dynamics of on-chip interference wavefronts between multiple plasmonic vortices was revealed by ultrafast time-resolved photoemission electron microscopy.Our nature-inspired optical vortex generator would facilitate various vortex-related optical applications,including structured wavefront shaping,free-space and plasmonic vortices,and high-capacity information metaphotonics. | Zhongwei Jin David Janoschka Junhong Deng Lin Ge Pascal Dreher Bettina Frank Guangwei Hu Jincheng Ni Yuanjie Yang Jing Li Changyuan Yu Dangyuan Lei Guixin Li Shumin Xiao Shengtao Mei Harald Giessen Frank Meyer zu Heringdorf Cheng-Wei Qiu | 2021 | eLight2021，1，1： | 3 |
| 4 | Soil Nutrient Distribution in Two Typical Paddy Terrace Wetlands Along an Elevation Gradient During the Fallow Period显示文摘Soil nutrient concentrations in the top soils from two paddy terraces were determined in order to investigate spatial distributions of soil nutrients along the elevations on the Yunnan plateau of China during the fallow period.Results showed that soil nutrients in both terraces were higher than the reference concentrations except for SOC,TN,TP and Fe.Soil macronutrients didn't show significant differences in both terraces except for Mg and Ca,so did soil micronutrients except for Mn.Spatial distribution patterns of soil nutrients along the increasing elevations were different in both terraces.However,soil nutrients in both terraces were generally not significantly influenced by the elevations and soil pH values.The findings of this study can contribute to soil fertility management and ecological protection of Hani terraces. | WANG Qinggai BAI Junhong HUANG Laibin DENG Wei XIAO Rong ZHANG Kejiang | 2011 | Journal of Mountain Science2011，8，3： | 2 |
| 5 | Large-scale achromatic flat lens by light frequency-domain coherence optimization显示文摘Flat lenses,including metalens and diffractive lens,have attracted increasing attention due to their ability to miniaturize the imaging devices.However,realizing a large scale achromatic flat lens with high performance still remains a big challenge.Here,we developed a new framework in designing achromatic multi-level diffractive lenses by light coherence optimization,which enables the implementation of large-scale flat lenses under non-ideal conditions.As results,a series achromatic polymer lenses with diameter from 1 to 10mm are successfully designed and fabricated.The subsequent optical characterizations substantially validate our theoretical framework and show relatively good performance of the centimeter-scale achromatic multi-level diffractive lenses with a super broad bandwidth in optical wavelengths(400-1100 nm).After comparing with conventional refractive lens,this achromatic lens shows significant advantages in white-light imaging performance,implying a new strategy in developing practical planar optical devices. | Xingjian Xiao Yunwei Zhao Xin Ye Chen Chen Xinmou Lu Yansen Rong Junhong Deng Guixin Li Shining Zhu Tao Li | 2022 | Light(Science & Applications)2022，11，12： | 2 |
| 6 | Gasdermins:pore-forming activities and beyond显示文摘Gasdermins(GSDMs)belong to a protein superfamily that is found only in vertebrates and consists of GSDMA,GSDMB,GSDMC,GSDMD,DFNA5(a.k.a.GSDME)and DFNB59(a.k.a.Pejvakin(PJVK))in humans.Except for DFNB59,all members of the GSDM superfamily contain a conserved twodomain structure(N-terminal and C-terminal domains)and share an autoinhibitory mechanism.When the N-terminal domain of these GSDMs is released,it possesses pore-forming activity that causes inflammatory death associated with the loss of cell membrane integrity and release of inflammatory mediators.It has also been found that spontaneous mutations occurring in the genes of GSDMs have been associated with the development of certain autoimmune disorders,as well as cancers.Here,we review the current knowledge of the expression profile and regulation of GSDMs and the important roles of this protein family in inflammatory cell death,tumorigenesis and other related diseases. | Zengzhang Zheng Wanyan Deng Xiwen Lou Yang Bai Junhong Wang Huasong Zeng Sitang Gong Xing Liu | 2020 | Acta Biochimica et Biophysica Sinica2020，52，5： | 2 |
| 7 | 实时荧光定量RT-PCR检测鼻咽癌Survivin mRNA基因表达(英文)显示文摘Objective: To establish the method of real time fluorescence quantitative RT-PCR for detecting the expression of Survivin mRNA in nasopharyngeal carcinoma (NPC) tissues. Methods: The total RNA was extracted from NPC cell line CNE-2 and tissues with Trizol and then been transcribed reversely to cDNA, a method of real time fluorescence quantitative RT-PCR for detecting the expression of Survivin mRNA in NPC tissues had been established, in which chronic nasopharyngitis patients' nasopharynx tissues treated as control group. Results: The expression of Survivin mRNA all could be detected either in CNE-2 cells, NPC tissues or in chronic nasopharyngitis patients' nasopharynx tissues, and there was higher the expression level of Survivin mRNA in NPC tissues than which in chronic nasopharyngitis patients' nasopharynx tissues, the difference was significant (P < 0.01). The expression of Survivin mRNA could be detected both in stage I + II and stage III + IV NPC, and there was no significant difference in relative quantifications of gene expression between these two groups (P > 0.05). There was no relationship between Survivin mRNA expression and age and sex of NPC patients (P > 0.05). Conclusion: Real time fluorescence quantitative RT-PCR is a rapid, effective and high sensitive method for detecting the expression of Survivin mRNA in NPC tissues. The overexpression of Survivin mRNA may play some roles in pathogenesis of NPC. | Shengmiao Fu Junhong Cai Zhihua Tu Yutian Wang Liqun Deng Zhu Liang Zhenqun Lin Xuanju Gong | 2008 | The Chinese-German Journal of Clinical Oncology2008，7，9： | 1 |
| 8 | Measurement of noise source impedance of SMPS using a two probes approach 显示文摘 | See Kye Yak Deng Junhong | 2004 | IEEE Transactions on Power Electronics2004，19，3： | 1 |
| 9 | Transrectal Ultrasound-guided Systematic 13-Core Prostate Biopsy to Diagnose Prostate Carcinoma显示文摘 | Liuping Yang Junhong Deng Hong Zhong Jianbo Hu Hongai Wei Liangsheng Wang | 2005 | Chinese Journal of Clinical Oncology2005，2，6： | 1 |
| 10 | Measurement of noise source impedance of SMPS using a two probe approach显示文摘 | See Kye Yak Deng Junhong | | 0，，03： | 1 |
| 11 | Measurement of noise source impedance of SMPS using a two current probes approach 显示文摘 | See K Y Deng Junhong | 2004 | IEEE Transactions on Power Electronics2004，19，3： | 1 |
| 12 | Immune‑Ageing Evaluation of Peripheral T and NK Lymphocyte Subsets in Chinese Healthy Adults显示文摘Ageing is often accompanied with a decline in immune system function,resulting in immune ageing.Numerous studies have focussed on the changes in different lymphocyte subsets in diseases and immunosenescence.The change in immune phenotype is a key indication of the diseased or healthy status.However,the changes in lymphocyte number and phenotype brought about by ageing have not been comprehensively analysed.Here,we analysed T and natural killer(NK)cell subsets,the phenotype and cell differentiation states in 43,096 healthy individuals,aged 20–88 years,without known diseases.Thirty-six immune parameters were analysed and the reference ranges of these subsets were established in different age groups divided into 5-year intervals.The data were subjected to random forest machine learning for immune-ageing modelling and confirmed using the neural network analysis.Our initial analysis and machine modelling prediction showed that na.ve T cells decreased with ageing,whereas central memory T cells(Tcm)and effector memory T cells(Tem)increased cluster of differentiation(CD)28-associated T cells.This is the largest study to investigate the correlation between age and immune cell function in a Chinese population,and provides insightful differences,suggesting that healthy adults might be considerably influenced by age and sex.The age of a person's immune system might be different from their chronological age.Our immune-ageing modelling study is one of the largest studies to provide insights into‘immune-age’rather than‘biological-age’.Through machine learning,we identified immune factors influencing the most through ageing and built a model for immune-ageing prediction.Our research not only reveals the impact of age on immune parameter differences within the Chinese population,but also provides new insights for monitoring and preventing some diseases in clinical practice. | Zhenghu Jia Zhiyao Ren Dongmei Ye Jiawei Li Yan Xu Hui Liu Ziyu Meng Chengmao Yang Xiaqi Chen Xinru Mao Xueli Luo Zhe Yang Lina Ma Anyi Deng Yafang Li Bingyu Han Junping Wei Chongcheng Huang Zheng Xiang Guobing Chen Peiling Li Juan Ouyang Peisong Chen Oscar Junhong Luo Yifang Gao Zhinan Yin | 2023 | Phenomics2023，3，4： | 1 |
| 13 | Measurement of noise source impedance of SMPS using a two probes approach显示文摘 | Deng Junhong | 2004 | IEEE Trans on Power Electronics2004，19，3： | 1 |
| 14 | Effects of Alpine Wetland Landscapes on Regional Climate on the Zoige Plateau of China显示文摘 | Junhong Bai Qiongqiong Lu Qingqing Zhao Junjing Wang Hua Ouyang Xiangzheng Deng | 2013 | Advances in Meteorology2013，，： | 1 |
| 15 | Water diffusion coefficients of horizontal soil columns from natural saline-alkaline wetlands in a semiarid area显示文摘 | Bai Junhong Deng Wei Cui Baoshan | 2007 | Eurasian Soil Science2007，40，6： | 1 |
| 16 | Measurement of noise source impedance of SMPS using a two probes approach显示文摘 | Junhong Deng | 2004 | IEEE Transactions on Power Electronics2004，19，3： | 1 |
| 17 | Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia显示文摘Aberrant self-renewal of leukemia initiation cells(LICs)drives aggressive acute myeloid leukemia(AML).Here,we report that UHRF1,an epigenetic regulator that recruits DNMT1 to methylate DNA,is highly expressed in AML and predicts poor prognosis.UHRF1 is required for myeloid leukemogenesis by maintaining self-renewal of LICs.Mechanistically,UHRF1 directly interacts with Sin3A-associated protein 30(SAP30)through two critical amino acids,G572 and F573 in its SRA domain,to repress gene expression.Depletion of UHRF1 or SAP30 derepresses an important target gene,MXD4,which encodes a MYC antagonist,and leads to suppression of leukemogenesis.Further knockdown of MXD4 can rescue the leukemogenesis by activating the MYC pathway.Lastly,we identified a UHRF1 inhibitor,UF146,and demonstrated its significant therapeutic efficacy in the myeloid leukemia PDX model.Taken together,our study reveals the mechanisms for altered epigenetic programs in AML and provides a promising targeted therapeutic strategy against AML. | Cheng-Long Hu Bing-Yi Chen Zijuan Li Tianbiao Yang Chun-Hui Xu Ruirui Yang Peng-Cheng Yu Jingyao Zhao Ting Liu Na Liu Bin Shan Qunling Zhang Junhong Song Ming-Yue Fei Li-Juan Zong Jia-Ying Zhang Ji-Chuan Wu Shu-Bei Chen Yong Wang Binhe Chang Dan Hou Ping Liu Yilun Jiang Xiya Li Xinchi Chen Chu-Han Deng Yi-Yi Ren Roujia Wang Jiacheng Jin Kai Xue Ying Zhang Meirong Du Jun Shi Ling-Yun Wu Chun-Kang Chang Shuhong Shen Zhu Chen Sai-Juan Chen Xiaolong Liu Xiao-Jian Sun Mingyue Zheng Lan Wang | 2022 | Cell Research2022，32，12： | 1 |
| 18 | Spatial and seasonal distribution of nitrogen in marsh soils of a typical floodplain wetland in Northeast China显示文摘 | BAI Junhong WANG Qinggai DENG Wei | 2012 | Environment Monitoring and Assessment2012，184，3： | 1 |
| 19 | Giant enhancement of second-harmonic generation from a nanocavity metasurface显示文摘Nonlinear plasmonic metasurfaces are compatible with complementary metal oxide semiconductor technology and highly promising for on-chip optical switching and modulations and nanoscale frequency conversions.However,the low nonlinearoptical response of metasurface devices limits their practical applications.To circumvent this constraint,we propose the design of a nanocavity plasmonic metasurface,in which the strong light localization in the nanocavity can be used to boost the efficiency of second-harmonic generation.Compared with the single-layer counterpart,experimental results show that the intensity of the second-harmonic waves in the nanocavity metasurface is enhanced by~790 times.The proposed nanocavity plasmonic metasurfaces in this work may open new routes for developing highly efficient nonlinear metacrystals for on-chip nonlinear sources,nonlinear image encryption,information processing,and so on. | Xuecai Zhang Junhong Deng Mingke Jin Yang Li Ningbin Mao Yutao Tang Xuan Liu Wenfeng Cai Yao Wang Kingfai Li Yanjun Liu Guixin Li | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，9： | 1 |
| 20 | Chiral nanoparticle-induced amplification in optical activity of molecules with chiral centers显示文摘Sensitive differentiation of an enantiomer from its mirror image(ie,enantiodifferentiation),a perennial challenge for pharmaceutical production and disease diagnosis,is technically limited by the weak optical activity(OA)of enantiomers,mainly due to their dimensional mismatch with light wavelengths in the ultraviolet(UV)-visible region.Here we use silver chiral nanoparticles(Ag CNPs)with nominally sub-5 nm helical pitch(P)to amplify the OA of(20R,30R,40S)-riboflavin-50-phosphate sodium salts(RP),which have been found to indirectly affect metabolic processes,through the formation of an RP thin film(TF)covering a close-packed array of Ag CNPs.The OA of the RP in the deep-UV region can be amplified up to 80-fold,ascribed to the aggregation of RP in the TFs and the interactions between RP and the atomically chiral lattices at the CNPs'surfaces.The former contribution,not associated with the chiral Ag topographies,plays a dominant role by thickening the RP TFs,so that the observed amplification has no enantioselective dependence on the chirality of the Ag CNPs.This study extends progress in the sensitive detection of bio-enantiomers,which is highly desired for advanced bio-detection in disease diagnosis and production of single-enantiomer pharmaceuticals. | Lin Yang Junjun Liu Junhong Deng Zhifeng Huang | 2020 | InfoMat2020，2，6： | 0 |
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