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3篇 您的检索式：作者名="Junjing Ding"

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		题名	作者	年代	出处	被引量
	1	Loss of the centrosomal protein Cenpj leads to dysfunction of the hypothalamus and obesity in mice显示文摘Cenpj is a centrosomal protein located at the centrosomes and the base of cilia,it plays essential roles in regulating neurogenesis and cerebral cortex development.Although centrosomal and cilium dysfunction are one of the causes of obesity,insulin resistance,and type 2 diabetes,the role that Cenpj plays in the regulation of body weight remains unclear.Here,we deleted Cenpj by crossing Cenpjflox/flox mice with Nkx2.1-Cre mice.Loss of the centrosomal protein Cenpj in Nkx2.1-expressing cells causes morbid obesity in mice at approximately 4 months of age with expended brain ventricles but no change of brain size.We found that hypothalamic cells exhibited reduced proliferation and increased apoptosis upon Cenpj depletion at the embryonic stages,resulting in a dramatic decrease in the number of Proopiomelanocortin(POMC)neurons and electrophysiological dysfunction of NPY neurons in the arcuate nucleus(ARC)in adults.Furthermore,depletion of Cenpj also reduced the neuronal projection from the ARC to the paraventricular nucleus(PVN),with decreased melanocortin-4 receptors(MC4R)expression in PVN neurons.The study defines the roles that Cenpj plays in regulating hypothalamus development and body weight,providing a foundation for further understanding of the pathological mechanisms of related diseases.	Wenyu Ding Changjiang Zhang Baisong Wang Xin Zhou Le Sun Suijuan Zhong Jing Liu Junjing Zhang Xiaoqun Wang Qian Wu	2021	Science China(Life Sciences)2021，64，3：	1
	2	Growth of High-Quality Multicrystalline Silicon Ingot through the Cristobalite Seeded Method显示文摘	Yunyang Yu Junjing Ding Wenliang Chen Zhaoyu Zhang Xucheng Zhou Genxiang Zhong Xinming Huang	2016	材料科学与工程(中英文B版)2016，6，6：	0
	3	Growth Process Improvement for Casting High-Performance Multi-Crystalline Silicon Ingots for Solar Cells显示文摘	Wenliang Chen Bing Zhou Junjing Ding Yunyang Yu Hui Dong Genxiang Zhong Xinming Huang	2016	材料科学与工程(中英文B版)2016，6，4：	0

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