维普期刊资源整合服务平台（V6.5）

213篇 您的检索式：作者名="KANAI F"

选中清除导出查看参考文献查看引证文献引用追踪共11页首页上一页第1页下一页末页 /11 跳转

	题名	作者	年代	出处	被引量
1	Unexpected metastasis of intraductal papillary neoplasm of the bile duct without an invasive component to the brain and lungs:A case report显示文摘BACKGROUND Despite an expanding number of studies on intraductal papillary neoplasm of the bile duct(IPNB),distant metastasis remains unexplained especially in cases of carcinoma in situ.In the present study,we report a rare and interesting case of IPNB without invasive components that later metastasized to lungs and brain.CASE SUMMARY A 69-year-old male was referred to our hospital due to suspected cholangiocarcinoma.Laboratory tests on admission reported a mild elevation of alkaline phosphatase,γ-glutamyl transpeptidase,and total bilirubin in serum.Endoscopic retrograde cholangiography revealed a filling defect in the common bile duct(CBD)extending to the left hepatic duct.Peroral cholangioscopy delineated a tumor in the CBD that had a papillary pattern.Multidetector computed tomography and magnetic resonance cholangiopancreatography detected partial blockage ot interlude in the CBD leading to cholestasis without evidence of metastasis.Therefore,a diagnosis of IPNB cT1N0M0 was established.Left hepatectomy with bile duct reconstruction was performed.Pathological examination confirmed an intraepithelial neoplasia pattern without an invasive component and an R0 resection achievement.The patient was monitored carefully by regular examinations.However,at 32 mo after the operation,a 26 mm tumor in the lungs and a 12 mm lesion in the brain were detected following a suspicious elevated CA 19-9 level.Video-assisted thoracoscopic surgery of left upper lobectomy and stereotactic radiotherapy are indicated.In addition to histopathological results,a genomic profiling analysis using whole exome sequencing subsequently confirmed lung metastasis originating from bile duct cancer.CONCLUSION This case highlights the important role of genomic profiling analysis using whole exome sequencing in identifying the origin of metastasis in patients with IPNB.	Nguyen Hai Nam Kojiro Taura Masashi Kanai Keita Fukuyama Norimitsu Uza Hirona Maeda Yojiro Yutaka Toyofumi F Chen-Yoshikawa Manabu Muto Shinji Uemoto	2020	World Journal of Gastroenterology2020，26，3：	5
2	Serumk-free coculture system fort ex vivo expansion of human cord blood primitive prohenitors and SCID mouse-reconstituting cells using human bone marrow primary stromall cells显示文摘	Yamaguchi M Hirayarna F Kanai M	2001	Exp Hematol2001，29，2：	1
3	Single small-interfering RNA expression vector for silencing multiple transforming growth factor-beta pathway components 显示文摘	Jazag A Kanai F Ijichi H	2005	Nucleic Acids Res2005，33，：	1
4	Proteomic analysis of the TGF - beta signaling pathway in pancreatic carcinoma cells u- sing stable RNA interference to silence Smad4 expression 显示文摘	IMAMURA T KANAI F KAWAKAMI T	2004	Bio- ehem Biophys Res Commun2004，318，1：	1
5	Adenovirus-mesdiated gane therapy of gastiric carcinoma using cancer-specific gene expression in vivo显示文摘	Tanaka T Kanai F Lan KH	1997	Biochem Biophy Res Commun1997，231，3：	1
6	Functional analysis of PIK3CA gene mutations in human colorectal cancer显示文摘	Ikenoue T Kanai F Hikiba Y	2005	Cancer Res2005，65，11：	1
7	Proteomic analysis of the TGF-beta signaling pathway in pancreatic carcinoma cells using stable RNA interference to silence Smad4 expression显示文摘	Imamura T Kanai F Kawakami T	2004	Biochem Biophys Res Commun2004，318，1：	1
8	Invivo adenovirus-mediated prodrug gene therapy for carcinoembryonic antigen-producing pancreatic cancer 显示文摘	Ohashi M Kanai F Tanaka T	1998	Jpn J Cancer Res1998，89，4：	1
9	Serum-free coculture system for ex vivo expansion of human cord blood primitive progenitors and SCID mousereconstituting cells using human bone marrow primary stromal cells显示文摘	Yamaguchi M Hirayama F Kanai M	2001	Exp Hematol2001，29，2：	1
10	显示文摘	Yamaguchi M Hirayama F Kanai M	2001	Exp Hematol2001，29，：	1
11	The scope and limits of top -down attention in uncon- scious visual processing 显示文摘	KANAI R TSUCHIYA N VERSTRATEN F A	2006	Curr Biol2006，16，23：	1
12	p53- Independent negative regulation of p21fcyclin dependent kinase-interacting protein 1 by the Sonic hedgehog-glioma-associated oncologenepathway in gastric carcinoma cells 显示文摘	Ohta M Tateishi K Kanai F	2008	Cancer Res2008，65，10：	1
13	Proteomic analysis of sera from hepatocellular carcinoma patients after radiofrequency ablation treatment 显示文摘	Kawakami T Hoshida Y Kanai F	2005	Proteomics2005，5，16：	1
14	14-3-3transits to the nucleus and participates in dynamic nucleocytoplasmic trans-port显示文摘	Brunet A Kanai F Stehn J	2002	J Cell Biol2002，156，5：	1
15	p53-Independent negative regulation of p21/cyclin-dependent kinase-interacting protein 1 by the sonic hedgehog-glioma-associated oncogene 1 pathway in gastric carcinoma cell显示文摘	OHTA M TATEISHI K KANAI F	2005	Caner Res2005，65，10：	1
16	Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-β显示文摘	Jazag A Ijichi H Kanai F	2005	Oncogene2005，24，4：	1
17	High prevalence of eytotoxin positive Helicobacter pylroi in patients unrelated to the presence of peptic ulcers in Japan显示文摘	Ogura K Kanai F Measa S	1997	Gut1997，41，：	1
18	Alterations in autonomic nervous control of heart rate among tourists at 2700 and 3700 m above sea level显示文摘	Kanai M Nishihara F Shiga T		0，，01：	1
19	Protcomic analysis of the TGF-beta signaling pathway in pancreatic carcinoma cells using stable RNA interference to silence Smad4 exprossion显示文摘	KANAI F KAWAKAMI T	2004	Biochem Biophys Res Commun2004，318，1：	1
20	Serum-free coculture system for ex vivo expansion of human cord blood primitive progenitors and SCID mouse-reconstituting cells using human bone marrow primary stromal cells显示文摘	Yamaguchi M Hirayama F Kanai M	2001	Exp Hematol2001，29，2：	1

返回顶部每页显示：

共11页首页上一页第1页下一页末页 /11 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示