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| 1 | p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival显示文摘响应 DNA 损坏的房间命运的中央仲裁人是 p53,它调整涉及房间周期拘捕,幸存和 apoptosis 的基因的表示。尽管 DNA 损坏开始的许多回答被描绘了,肌动朊细胞骨架管理者的角色大部分是未知的。我们现在显示出那 RhoC 和秘鲁利玛机场之代号 kinase (LIMK2 ) 2 是 genotoxic 代理人导致的直接 p53 目标基因。尽管 RhoC 和 LIMK2 在肌动朊细胞骨架规定有生长得很好的角色,我们的结果显示 LIMK2 的激活也有支持幸存的功能追随者 DNA 损坏。由调停 siRNA 的击倒或选择的药理学封锁的 LIMK 抑制敏化房间到无线电 -- 或化疗,以便当与 LIMK 抑制结合了时,当单身地管理了时,是尚不致命的治疗导致了房间死亡。我们的调查结果建议把 LIMK 禁止者与 genotoxic 治疗相结合能比单个代理人的管理更有效,并且加亮在肌动朊细胞骨架管理者和 DNA 之间的一个新奇连接导致损坏的房间幸存机制。 | Daniel R Croft Diane Crighton Michael S Samuel Filipe C Lourenco June Munro Jenifer Wood Karim Bensaad Karen H Vousden Owen J Sansom Kevin M Ryan Michael F Olson | 2011 | Cell Research2011，21，4： | 3 |
| 2 | Efficient hydrogen peroxide decomposition on bimetallic Pt-Pd surfaces 显示文摘 | Hasnat M A Rahrnan M Maria Borhanuddin S M Siddiqua Ayesha Bahadur N M Karim M R | 2010 | Catalysis Communications2010，12，4： | 1 |
| 3 | A new impulse detector for switching median filters显示文摘 | ZHANG S KARIM M A | 2002 | IEEE Signal Processing Letters2002，9，： | 1 |
| 4 | A short review of the impact and management of weedy rice 显示文摘 | KARIM S M R ISMAIL B S AZMI M | 2006 | Plant Protection Quarterly2006，21，： | 1 |
| 5 | A new impulse detector for switching median filters显示文摘 | Zhang S Karim M A | 2002 | IEEE Signal Processing Letters2002，9，11： | 1 |
| 6 | Arithmetic processing with a joint-transform correlator 显示文摘 | Alam M S Karim M A | 1992 | Appl Opt1992，31，23： | 1 |
| 7 | A new impulse detector for switching median filters显示文摘 | Zhang S Karim M A | 2002 | IEEE Signal Proc2002，9，： | 1 |
| 8 | Taxodiorte and taxodone, two rtovel diterpenoid quirtorte methide tumor itthibitors from Taxodium distichum 显示文摘 | KUPCHAN S M KARIM A MARCKS C | 1968 | Journal of the American Chemical Society1968，90，21： | 1 |
| 9 | Genetics of resistance of rice cultivar ARC10550 to Bangladesh brown pianthopper teletype显示文摘 | Gurdev S Khush A N M Rezaul Karim E R Angeles | 1985 | Journal of Genetics (-)1985，，2： | 1 |
| 10 | An Improved Low-power High-throughput Log-MAP Turbo Decoder显示文摘 | Karim S M Chakrabarti I | 2010 | IEEE Trans on Consumer Electronics2010，56，2： | 1 |
| 11 | A new impulse detector for switc- hing median filters 显示文摘 | Zhang S Karim M | 2002 | IEEE Signal Processing Let- ters2002，9，11： | 1 |
| 12 | Fringe-adjusted joint transform correlation显示文摘 | ALAM M S KARIM M A | 1993 | Apply Optic1993，32，23： | 1 |
| 13 | Effect of diferent levels of concentrate allowances on rumen fluid pH,nutrient digestion,nitrogen retention and growth performance of weaner lambs显示文摘 | Tripathi M K Chamrvedi O H Karim S A | 2007 | Small Rumm Res2007，72，： | 1 |
| 14 | Predicting the long-term performance of a wideembankment on soft soil unsing an elastic-viscoplasticmodel显示文摘 | KARIM M R GNANENDRAN CT LO S C R | 2010 | Canada Geotechnical Journal2010，47，： | 1 |
| 15 | Empirical relationships between some manufacturing practices & performance 显示文摘 | KARIM M A SMITH A J R HALGAMUGE S | 2008 | Int J Production Res2008，46，13： | 1 |
| 16 | Structural and Electrical Characteristics of Nanocrystalline Silicon Prepared by Hot-wire ChemicalVapor Deposition on Polymer Substrates显示文摘 | Adachia M M Kavanagh K L Karim K S | 2008 | Thin Solid Films2008，516，： | 1 |
| 17 | Risk factors of diabetic retinopathy in Bangladeshi type 2diabetic patients显示文摘 | Ahmed K R Karim M N Bukht M S | 2011 | Diabetes&Metabolic Syndrome:Clinical Research&Reviews2011，5，4： | 1 |
| 18 | Preparation of conducting polyaniline/ TiO2 composite submieron-rods by the 7 radiotysis oxidative polymerization method显示文摘 | Karim M R Yeum J H Lee M S | 2008 | ReactFunct Polym2008，68，13： | 1 |
| 19 | A new impluse detector for switchiing median filter显示文摘 | Zhang S Karim M | 2002 | IEEE Signal Processing Letters2002，9，11： | 1 |
| 20 | A new impulse detector for switching median filters 显示文摘 | Zhang S Karim M A | 2002 | IEEE Signal Process Letters2002，9，11： | 1 |
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