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| 1 | Increased prevalence of intestinal inflammation in patients with liver cirrhosis显示文摘AIM To investigate the pathophysiology of the digestive tract in patients with liver cirrhosis.METHODS In 42 cirrhotic patients and 20control subjects, the following fecal proteinswere measured by enzyme-linkedimmunosorb6nt assay: albumin (Alb ),transferrin (Tf), and al-antitrypsin (a,-AT) as amarker for intestinal protein l0ss, hemoglobin(Hb) for bleeding, PMN-eIastase for intestinalinflammation, and secretory lgA for intestinalimmunity.RESULTS The fecaI concentrations of Hb, Alb,Tf, al-AT, and PMN’eIastase were increased in13 (3l%), 8(19%), l0(24%), 6(14%), and 1l(26%) cases among 42 patients, resPectiveIy.F6cal concentration of secretory IgA wasdecreased in 7 (l7%) of 42 patients. However,these fecal concentrations were not related tothe severity or etiology of liver cirrhosis. Theserum Alb level was significantIy decreased inpatients with intestinal protein Ioss c0mpared tothat in patients without intestinal protein loss.CONCLUSION These findings suggest that: rob6sides the weIl’known pathological conditions,Such as bleeding and protein loss, intestinaIinflammati0n and decreased intestinaI immunityare found in cirrhotic patients, @ intestinalprotein loss contributes to hypoalbuminemia incirrhotic patients, and @ intestinaI inflammationshouId not b6 0verlooked in cirrhotic patients,since it may contribute to or cause intestinalprotein Ioss and oth6r various pathologicalconditions. | Saitoh O Sugi K Lojima K Matsumoto H Nakagawa K Kayazawa M Tanaka S Teranishi T Hirata I Katsu Ki K | 1999 | World Journal of Gastroenterology1999，5，5： | 2 |
| 2 | NADPH oxidase mediates striatal neuronal injury after transient global cerebral ischemia 显示文摘 | YOSHIOKA H NIIZUMA K KATSU M | 2011 | J Cereb Blood Flow Metab2011，31，3： | 1 |
| 3 | Isolation and characterization of goldfish Y box protein, a germ- cell-specific RNA-hinding protein 显示文摘 | Katsu Y Yamashita M Nagahama Y | 1997 | European Journal of Biochemistry1997，249，3： | 1 |
| 4 | Hemoglobin-in- duced oxidative stress contributes to matrix metallopro- teinase activation and blood-brain barrier dysfunction in vi- vo显示文摘 | Katsu M Niizuma K Yoshioka H | 2010 | J Cereb Blood Flow Metab2010，30，12： | 1 |
| 5 | Hemoglobin- induced oxidative stress contributes to matrix metalloproteinase activation and blood- brain barrier dysfunction in vivo显示文摘 | Katsu M Niizuma K Yoshioka H | 2010 | J Cereb Blood Flow Metab2010，30，12： | 1 |
| 6 | NADPH oxidase mediatesstriatal neuronal injury after transient global cerebral ischemia显示文摘 | Yoshioka H Niizuma K Katsu M | 2010 | JCerebr Blood F Met2010，31，3： | 1 |
| 7 | NADPH oxidase mediates striatal neuronal injury after transient global cerebral ischemia显示文摘 | Yoshioka H Niizuma K Katsu M | 2011 | J Cereb Blood Flow Metab2011，31，： | 1 |
| 8 | NADPH oxidase mediates striatal neuronal injury after transient global cerebral ischemia 显示文摘 | Yoshioka H Niizuma K Katsu M | 2011 | J Cereb Blood Flow Metab2011，31，3： | 1 |
| 9 | Determination of the pH difference across a cell membrane using a methylammonium-selective membrane electrode显示文摘 | Katsu T Akagi M Hiramatsu T | | 0，，： | 1 |
| 10 | Isolation and characterization of goldfish cdc2,a catalytic component of maturation-promoting factor显示文摘 | Kajiura H Yamashita M Katsu Y | 1993 | Dev Growth Differ1993，35，： | 1 |
| 11 | Behavior of three compoments of maturation-promoting factor,cdc2 kinase and cyclin B,during oocyte maturation of goldfish显示文摘 | Katsu Y Yamashita M Kajiura H | 1993 | Dev Biol1993，160，： | 1 |
| 12 | Hemoglobin-induced oxidative stress contributes to matrix metalloproteinase activation and blood-brain barrier dysfunction in vivo显示文摘 | Katsu M Niizuma K Yoshioka H | | 0，，12： | 1 |
| 13 | Hemoglobin-induced oxidative stress contributes to matrix metallopro- teinase activation and blood-brain barrier dysfunction in vivo显示文摘 | Katsu M Niizuma K Yoshioka H | 2010 | J Cereb Blood Flow Metab2010，30，12： | 1 |
| 14 | Consistent injury to medium spiny neurons and white matter in the mouse striatum after prolonged transient global cerebral ischemia显示文摘 | Yoshioka H Niizuma K Katsu M | 2011 | J Neurotrauma2011，28，： | 1 |
| 15 | Behavior of the components of maturation-promoting factor, cdc2 kinase and cyclin-B, during oocyte maturation of goldfish显示文摘 | Katsu Y Yamashita M Kajiura H | 1993 | Developmental biology1993，160，1： | 1 |
| 16 | Interaction of 1-dodecy-lazacycloheptan-2-one(Azone)with erythrocyte membrane显示文摘 | Katsu T Kuroko M Sanchika K | 1989 | Inte J Pharm1989，53，1： | 1 |
| 17 | Recovery of cardiomegaly after treatment of traumatic popliteal arteriovenous fistula 显示文摘 | Shindo S Honda Y Katsu M | 2009 | Circ J2009，73，4： | 1 |
| 18 | New antimicrobial agents series XXXIV: isepamicin 显示文摘 | Katsu M Saito A | 1989 | Jpn J Antihiot1989，42，3： | 1 |
| 19 | NADPH oxidase mediates striatal neuronal injury after transient global cerebral is- chemia显示文摘 | YOSHIOKA H NIIZUMA K KATSU M | 2011 | J Cereb Blood Flow Metab2011，31，3： | 1 |
| 20 | Isolation and characterization of goldfish Y-box protein, a germ-cell-specific RNA-binding protein 显示文摘 | Katsu Y Yamashita M Nagahama Y | 1997 | Eur J Biochem1997，249，3： | 1 |
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