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| 1 | Edge computing technologies for Internet of Things: a primer显示文摘 | Yuan Ai Mugen Peng Kecheng Zhang | 2018 | Digital Communications and Networks2018，4，2： | 11 |
| 2 | Allogeneic Vγ9Vδ2 T-cell immunotherapy exhibits promising clinical safety and prolongs the survival of patients with late-stage lung or liver cancer显示文摘Vγ9Vδ2 T cells are promising candidates for cellular tumor immunotherapy.Due to their HLA-independent mode of action,allogeneic Vγ9Vδ2 T cells can be considered for clinical application.To apply allogeneic Vγ9Vδ2 T cells in adoptive immunotherapy,the methodology used to obtain adequate cell numbers with optimal effector function in vitro needs to be optimized,and clinical safety and efficacy also need to be proven.Therefore,we developed a novel formula to improve the expansion of peripheralγδT cells from healthy donors.Then,we used a humanized mouse model to validate the therapeutic efficacy of expandedγδT cells in vivo;furthermore,the expandedγδT cells were adoptively transferred into late-stage liver and lung cancer patients.We found that the expanded cells possessed significantly improved immune effector functions,including proliferation,differentiation,and cancer cell killing,both in vitro and in the humanized mouse model.Furthermore,a phase I clinical trial in 132 late-stage cancer patients with a total of 414 cell infusions unequivocally validated the clinical safety of allogeneic Vγ9Vδ2 T cells.Among these 132 patients,8 liver cancer patients and 10 lung cancer patients who received≥5 cell infusions showed greatly prolonged survival,which preliminarily verified the efficacy of allogeneic Vγ9Vδ2 T-cell therapy.Our clinical studies underscore the safety and efficacy of allogeneic Vγ9Vδ2 T-cell immunotherapy,which will inspire further clinical investigations and eventually benefit cancer patients. | Yan Xu Zheng Xiang Mohammed Alnaggar Léonce Kouakanou Jiawei Li Junyi He Jiashuang Yang Yi Hu Yan Chen Li Lin Jianlei Hao Jingxia Li Jibing Chen Man Li Qingling Wu Christian Peters Qinghua Zhou Jianshuang Li Yingqing Liang Xiaohua Wang Baohui Han Meili Ma Dieter Kabelitz Kecheng Xu Wenwei Tu Yangzhe Wu Zhinan Yin | 2021 | Cellular & Molecular Immunology2021，18，2： | 8 |
| 3 | Progress on design and related R&D activities for the water-cooled breeder blanket for CFETR显示文摘The water-cooled ceramic breeder (WCCB) blanket is one of the blanket candidates for Chinese fusion engineering testing reactor (CFETR) and is being developed at the Institute of Plasma Physics, Chinese Academy of Sciences (ASIPP). This paper reviews design and evolution of the WCCB blanket for CFETR, and presents a new WCCB blanket design according to the latest CFETR core parameters (major and minor radii are R = 7.2 m and a = 2.2 m, respectively) and missions. This new design is expected to satisfy multiple CFETR operation modes of 0.2, 0.5, 1.0, and 1.5 GW fusion power and achieve tritium self-sufficiency. The feasibility of the updated blanket design is evaluated from the aspects of neutronics and thermo-hydraulics. Furthermore, the research and development (R&D) activities supporting to the WCCB blanket for CFETR are reported, including the design code, the water loop experiments, the pebble bed modeling and experiments, and the components fabrication technology. | Songlin Liu Xiaoman Cheng Xuebin Ma Lei Chen Kecheng Jiang Xia Li Hui Bao Jichao Wang Wanjing Wang Changhong Peng Peng Lu Min Li Kai Huang | 2019 | Theoretical & Applied Mechanics Letters2019，9，3： | 6 |
| 4 | Danggui-shaoyao-san, a traditional Chinese medicine prescription, alleviates the orthodontic pain and inhibits neuronal and microglia activation显示文摘 | Li Hongshi Gu Zexu Wu Li'an Xia Liang Zhou Kecheng E Lingling Wang Dongsheng Kou Junping Liu Hongchen | 2014 | Chinese Medical Journal2014，，20： | 4 |
| 5 | Recent progress of composite solid polymer electrolytes for all-solid-state lithium metal batteries显示文摘In comparison with lithium-ion batteries(LIBs)with liquid electrolytes,all-solid-state lithium batteries(ASSLBs)have been considered as promising systems for future energy storage due to their safety and high energy density.As the pivotal component used in ASSLBs,composite solid polymer electrolytes(CSPEs),derived from the incorporation of inorganic fillers into solid polymer electrolytes(SPEs),exhibit higher ionic conductivity,better mechanical strength,and superior thermal/electrochemical stability compared to the single-component SPEs,which can significantly promote the electrochemical performance of ASSLBs.Herein,the recent advances of CSPEs applied in ASSLBs are presented.The effects of the category,morphology and concentration of inorganic fillers on the ionic conductivity,mechanical strength,electrochemical window,interfacial stability and possible Li+transfer mechanism of CSPEs will be systematically discussed.Finally,the challenges and perspectives are proposed for the future development of high-performance CSPEs and ASSLBs. | Qingjiang Yu Kecheng Jiang Cuiling Yu Xianjin Chen Chuanjian Zhang Yi Yao Bin Jiang Huijin Long | 2021 | Chinese Chemical Letters2021，32，9： | 4 |
| 6 | Electrolyte for lithium protection: From liquid to solid显示文摘Lithium battery with high energy density and enhanced safety is undoubtedly the ideal choice for consumer electronics and electric vehicles.Metal anode such as lithium has been considered as the most effective way to enhance the energy density as it provides ultra-high theoretical capacity and the lowest redox potential.However,due to the low coulombic efficiency as well as safety concerns originated from dendrite issue of lithium,its further commercial utilization is hindered.Dendrite growth is a common phenomenon in metal electrodeposition while the plating process of Li is more complicated than other metals for its high reactivity nature.As a matter of fact,the Li plating process is accompanied with the generation of solid electrolyte interphase(SEI)in which the electrolyte plays a vital role.In this paper,recent advances of electrolytes for Li protect application are reviewed,from liquid to gel polymer and solid state,on which we find that although tremendous progress has been accomplished,there are still great challenges before Li metal anode could be commercially used. | Xiaohong Wu Kecheng Pan Mengmin Jia Yufei Ren Hongyan He Lan Zhang Suojiang Zhang | 2019 | Green Energy & Environment2019，4，4： | 4 |
| 7 | Proteomics provides individualized options of precision medicine for patients with gastric cancer显示文摘While precision medicine driven by genome sequencing has revolutionized cancer care,such as lung cancer,its impact on gastric cancer(GC)has been minimal.GC patients are routinely treated with chemotherapy,but only a fraction of them receive the clinical benefit.There is an urgent need to develop biomarkers or algorithms to select chemo-sensitive patients or apply targeted therapy.Here,we carried out retrospective analyses of 1,020 formalin-fixed,paraffin-embedded GC surgical resection samples from 5 hospitals and developed a mass spectrometry-based workflow for proteomic subtyping of GC.We identified two proteomic subtypes:the chemo-sensitive group(CSG)and the chemo-insensitive group(CIG)in the discovery set.The 5-year overall survival of CSG was significantly improved in patients who had received adjuvant chemotherapy after surgery compared with those who received surgery only(64.2%vs.49.6%;Cox P-value=0.002),whereas no such improvement was observed in CIG(50.0%vs.58.6%;Cox P-value=0.495).We validated these results in an independent validation set.Further,differential proteome analysis uncovered 9 FDA-approved drugs that may be applicable for targeted therapy of GC.A prospective study is warranted to test these findings for future GC patient care. | Wenwen Huang Dongdong Zhan Yazhuo Li Nairen Zheng Xin Wei Bin Bai Kecheng Zhang Mingwei Liu Xuefei Zhao Xiaotian Ni Xia Xia Jinwen Shi Cheng Zhang Zhihao Lu Jiafu Ji Juan Wang Shiqi Wang Gang Ji Jipeng Li Yongzhan Nie Wenquan Liang Xiaosong Wu Jianxin Cui Yongsheng Meng Feilin Cao Tieliu Shi Weimin Zhu Yi Wang Lin Chen Qingchuan Zhao Hongwei Wang Lin Shen Jun Qin | 2021 | Science China(Life Sciences)2021，64，8： | 3 |
| 8 | Vibrational characteristics of rotating soft cylinders显示文摘Rotating structural components are omnipresent in engineering structures and natural world. This work investigates the effects of the centrifugal and Coriolis forces on the free vibrational characteristics of soft cylinders rotating with respect to the axis of symmetry based on the nonlinear elasticity and linear incremental theories. The formulations indicate that the biasing deformation, instantaneous elastic moduli, and incremental equations of motion strongly depend on the rotating speed. The characteristic equation for the natural frequency is derived using the state-space method and approximate laminate technique.The numerical examples included in this work demonstrate that the centrifugal and Coriolis forces might have significant effects on the vibrational characteristics of the cylinder. Results of this work will benefit the design and control of novel engineering systems with rotating soft cylinders or shafts. | Kecheng Li Yinnan Zhang Haifei Zhan Yangkun Du Chaofeng Li | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，5： | 2 |
| 9 | Femtosecond Studies on Third-Order Optical Nonlinearities of Polyanilines显示文摘The ultrafast dynamics of third order nonlinearities of polyaniline(PAn)and polyaniline doped in polymethyl mathacrylate(PAn-PMMA)films are investigated using femtosecond absorption spectroscopy.An ultrafast initial exciton deformation time of about 100fs is observed in PAn film.In PAn-PMMA film,the third-order nonlinearity results in an efficient two-photon absorption at about 2eV. | WANG Hui LAI Tianshu LIN Weizhu MO Dang OUYANG Meng GONG Kecheng | 1994 | Chinese Physics Letters1994，11，8： | 2 |
| 10 | Energy utilization evaluation of CCHP systems显示文摘 | Hui Li Lin Fu Kecheng Geng Yi Jiang | 2005 | Energy & Buildings2005，，3： | 2 |
| 11 | Tribological Properties of Lubricating Oils with Triethanolamine Borate under Electromagnetic Field显示文摘Tribological properties of 150SN mineral oil and lubricating oils containing triethanolamine borate(TBE)with and without electromagnetic field impact were evaluated on a modified four-ball tribo-tester.The characteristics of the worn surfaces were studied by scanning electronic microscopy(SEM),energy dispersive spectrometry(EDS)and X-ray photoelectron spectroscopy(XPS).Moreover,the tribological mechanisms are discussed from the viewpoint of physical effect and chemical effect.The results indicated that the friction coefficients and wear scar diameters(WSDs)lubricated by 150SN mineral oil under electromagnetic field were higher than those without electromagnetism impact.The WSDs of steel balls lubricated by TBE-doped oils under electromagnetic field were smaller than those obtained from non-electromagnetic field,but the friction coefficients were higher than those under non-electromagnetic field.A protective coating consists of wear particles could be formed on the frictional surface due to the physical effect of electromagnetic field on wear debris.The electromagnetic field could facilitate the interaction of elemental boron and nitrogen in TBE with metal interfaces,and contributes to forming tribo-chemical reaction film to reduce friction and wear. | Wang Xin Fang Jianhua Jiang Zeqi Gu Kecheng Liu Ping | 2019 | China Petroleum Processing & Petrochemical Technology2019，21，3： | 2 |
| 12 | Cyclic Ether Contaminant Removal from Water Using Nonporous Adaptive Pillararene Crystals via Host-Guest Complexation at the Solid-Solution Interface显示文摘Te removal of soluble cyclic ether contaminants,such as dioxane and THF,produced in industrial chemical processes from water is of great importance for environmental protection and human health.Here we report that nonporous adaptive crystals of perethylated pillar[5]arene(EtP5)and pillar[6]arene(EtP6)work as adsorbents for cyclic ether contaminant removal via hostguest complexation at the solid-solution interface.Nonporous EtP6 crystals have the ability to adsorb dioxane from water with the formation of 1:2 host-guest complex crystals,while EtP5 crystals cannot.However,both guest-free EtP5 and EtP6 crystals remove THF from water with EtP5 having a better capacity.Tis is because EtP5 forms a 1:2 host-guest complex with THF via host-guest complexation at the solid-solution interface while EtP6 forms a 1:1 host-guest complex with THF.EtP6 also shows the ability to selectively remove dioxane from water even in the presence of THF.Moreover,the reversible transitions between nonporous guestfree EtP5 and EtP6 structures and guest-loaded structures make them highly recyclable. | Yujuan Zhou Kecheng Jie Run Zhao Errui Li Feihe Huang | 2019 | Research2019，，1： | 2 |
| 13 | Synthesis of a polyaniline-intercalated graphite oxide nanocomposite by an in situ oxidative polymerization reaction显示文摘 | Pinggui Liu Kecheng Gong | 1999 | Carbon1999，37，4： | 1 |
| 14 | Effect of B203 and CuO additions on the sintering temperature and microwave dielectric properties of 3Li20-Nb205 3TiO2 ceramics显示文摘 | Huanfu Zhou Hong Wang Kecheng Li | 2009 | Journal of Materials Science:Mater Electron2009，20，： | 1 |
| 15 | The Efficacy Evaluation of Cryosurgery in Pancreatic Cancer Patients with the Expression of CD44v6, Integrin-β1, CA199, and CEA显示文摘 | Gang Zhou David Chiu Dajiang Qin Lizhi Niu Jinlei Cai Lihua He Wenhao Huang Kecheng Xu | 2012 | Molecular Biotechnology2012，，1： | 1 |
| 16 | A Multi-agent Decision Support System for Stock Trading显示文摘 | Luo Yuan Liu Kecheng Davis D N | 2002 | IEEE Network2002，01，02： | 1 |
| 17 | Preparation and dynamic mechanical properties of poly(styrene-b-butadiene)-modified clay nanocomposites 显示文摘 | Chen Zhonghua Gong Kecheng | 2002 | Journal of Applied Polymer Science2002，84，8： | 1 |
| 18 | Preparation and Tribological Behavior of Hydrophobic Lanthanum Borate Nanosheets in Rapeseed Oil显示文摘Oleic acid-capped lanthanum borate(abbreviated as OA/La BO_3·H_2O) nanosheets were prepared by the hydrothermal method. The microstructures of as-prepared OA/La BO_3·H_2O were characterized by means of SEM, TEM, EDS, FTIR and XRD, respectively. Moreover, the friction and wear properties of OA/La BO_3·H_2O as a lubricant additive in rapeseed oil were evaluated on a four-ball tribotester. The tribochemical characteristics of worn surfaces were investigated by SEM and XPS. The results showed that the hydrophobic OA/La BO_3·H_2O nanosheets exhibited their morphology with a diameter in the range of 100 nm to 300 nm and a thickness of about 25 nm, and displayed excellent dispersing stability in rapeseed oil. In the meantime, the rapeseed oil doped with OA/La BO_3·H_2O nanosheets markedly decreased the friction and wear of steel balls, and the optimal friction-reducing and antiwear ability of rapeseed oil was obtained at an OA/La BO_3·H_2O content of 1.0%. The outstanding tribological performance of OA/La BO_3·H_2O in rapeseed oil was attributed to the formation of a composite boundary lubrication film mainly composed of lubricious tribochemical species of B_2O_3, La_2O_3 and Fe_2O_3, and deposits of OA/La BO_3·H_2O nanosheets as well as the adsorbates of rapeseed oil on rubbed surfaces. | Gu Kecheng Chen Boshui Xue Ming Wang Jiu Fang Jianhua Wu Jiang | 2016 | China Petroleum Processing & Petrochemical Technology2016，18，2： | 1 |
| 19 | 显示文摘 | Xiao Min Feng Bo Gong Kecheng | 2002 | Energy Conversion and Management2002，43，： | 1 |
| 20 | Preparation and dynamic-mechanical properties of poly(styrene-b-butadiene)/modified clay nanocomposites 显示文摘 | Chen Zhonghua Gong Kecheng | 2002 | Appl Polym Sci2002，84，： | 1 |
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