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| 1 | Biliary microlithiasis,sludge,crystals, microcrystallization,and usefulness of assessment of nucleation time显示文摘BACKGROUND:The process of microcrystallization,its sequel and the assessment of nucleation time is ignored.This systematic review aimed to highlight the importance of biliary microlithiasis,sludge,and crystals,and their association with gallstones,unexplained biliary pain,idiopathic pancreatitis, and sphincter of Oddi dysfunction.DATA SOURCES:Three reviewers performed a literature search of the PubMed database.Key words used were'biliary microlithiasis','biliary sludge','bile crystals','cholesterol crystallisation','bile microscopy','microcrystal formation of bile','cholesterol monohydrate crystals','nucleation time of cholesterol','gallstone formation','sphincter of Oddi dysfunction'and'idiopathic pancreatitis'.Additional articles were sourced from references within the studies from the PubMed search.RESULTS:We found that biliary microcrystals account for almost all patients with gallstone disease,7%to 79%with idiopathic pancreatitis,83%with unexplained biliary pain, and 25%to 60%with altered biliary and pancreatic sphincter function.Overall,the detection of biliary microcrystals in gallstone disease has a sensitivity ranging from 55%to 87%and a specificity of 100%.In idiopathic pancreatitis,the presence of microcrystals ranges from 47%to 90%.A nucleation time less than 10 days in hepatic bile or ultra-filtered gallbladder bile has a specificity of 100%for cholesterol gallstone disease.CONCLUSIONS:Biliary crystals are associated with gallstone disease,idiopathic pancreatitis,sphincter of Oddi dysfunction, unexplained biliary pain,and post-cholecystectomy biliary pain.Pathways of cholesterol super-saturation,crystallisation, and gallstone formation have been described with scientificsupport.Bile microscopy is a useful method to detect microcrystals and the assessment of nucleation time is a good method of predicting the risk of cholesterol crystallisation. | Vasitha Abeysuriya Kemal I Deen Navarathne MM Navarathne | 2010 | Hepatobiliary & Pancreatic Diseases International2010,9,3: | 13 |
| 2 | Colorectal cancer in the young,many questions,few answers显示文摘At a time where the incidence of colorectal cancer,a disease predominantly of developed nations,is showing a decline in those 50 years of age and older,data from the West is showing a rising incidence of this cancer in young individuals.Central to this has been the 75% increase in rectal cancer incidence in the last four decades.Furthermore,predictive data based on mathematical modelling indicates a 124 percent rise in the incidence of rectal cancer by the year 2030-a statistic that calls for collective global thought and action.While predominance of colorectal cancer(CRC) is likely to be in that part of the large bowel distal to the splenic flexure,which makes flexible sigmoidoscopic examination an ideal screening tool,the cost and benefit of mass screening in young people remain unknown.In countries where the incidence of young CRC is as high as 35% to 50%,the available data do not seem to indicate that the disease in young people is one of high red meat consuming nations only.Improvement in our understanding of genetic pathways in the aetiology of CRC,chiefly of the MSI,CIN and CIMP pathway,supports the notion that up to 30% of CRC is genetic,and may reflect a familial trait or environmentally induced changes.However,a number of other germline and somatic mutations,some of which remain unidentified,may play a role in the genesis of this cancer and stand in the way of a clear understanding of CRC in the young.Clinically,a proportion of young persons with CRC die early after curative surgery,presumably from aggressive tumour biology,compared with the majority in whom survival after operation will remain unchanged for five years or greater.The challenge in the future will be to determine,by genetic fingerprinting or otherwise,those at risk of developing CRC and the determinants of survival in those who develop CRC.Ultimately,prevention and early detection,just like for those over 50 years with CRC,will determine the outcome of CRC in young persons.At present,aside from those with an established familial tendency,there is no consensus on screening young persons who may be at risk.However,increasing awareness of this cancer in the young and the established benefit of prevention in older persons,must be a message that should be communicated with medical students,primary health care personnel and first contact doctors.The latter constitutes a formidable challenge. | Kemal I Deen Hiroshi Silva Raeed Deen Pramodh C Chandrasinghe | 2016 | World Journal of Gastrointestinal Oncology2016,8,6: | 2 |
| 3 | The Prevalence of Demodex folliculorum in blepharitis patients and the normal population显示文摘 | Kemal M Sumer Z Toker M I | 2005 | Ophthalmic Epidemiol2005,12,4: | 1 |
| 4 | Matching of separately excited DC motors to photovoltaic generators for maximum power output 显示文摘 | Akbaba M Qambe I Kemal A | 1998 | Solar Energy1998,63,6: | 1 |
| 5 | Tougheningof polyvinylchloride through the addition of nanoparticulate calcium carbonate 显示文摘 | KEMAL I WHITTLE A BURFORD R | 2009 | Polymer2009,50,: | 1 |
| 6 | Elevated serum neutrophil to lymphocyte and platelet to lymphocyte ratios could be useful in lung cancer diagnosis 显示文摘 | Kemal Y1 Yucel I Ekiz K | 2014 | Asian Pac J Cancer Prev2014,15,6: | 1 |
| 7 | Toughening of unmodified polyvinylchloride through the addition of nanoparticulate calcium carbonate显示文摘 | KEMAL I WHITTLE A BURFORD R | 2009 | Polymer2009,50,16: | 1 |
| 8 | Levatiracetam for the man- agement of Lance-Adams syndrome显示文摘 | Ilik F Kemal Ilik M C6ven I | 2014 | Iran J Child Neu- rol2014,8,2: | 1 |
| 9 | Elevated serum neutrophil to lym- phocyte and platelet to lymphocyte ratios could be useful in lung cancer diagnosis 显示文摘 | Kemal Y Yucel I Ekiz K | 2014 | Asian Pac J Cancer Prev2014,15,6: | 1 |
| 10 | Toughening of unmodifiedpolyvinyl chloride through the addition of nano-particulate calciumcarbonate显示文摘 | Kemal I Whittle A Yurford R | 2009 | Polymer2009,50,40: | 1 |
| 11 | Toughening of unmodifiedpolyvinyl chloride through the addition of nanoparticulate calciumcarbonate and titanatc coupling agent显示文摘 | Kemal I Whittle A Yurford R | 2013 | Journal of Applied PolymerScience2013,127,23: | 1 |
| 12 | Toughening of polyvinylchloride through the addition of nanoparticulate calcium carbonate显示文摘 | Kemal I Whittle A Burford R | 2009 | Polymer2009,50,: | 1 |
| 13 | Elevated Serum Neutrophil to Lymphocyte and Platelet to Lymphocyte Ratios Could be Useful in Lung Cancer Diagnosis显示文摘 | Kemal Y Yucel I Ekiz K | 2014 | Asian Pae J Cancer Prey2014,15,6: | 1 |
| 14 | Toughening of polyvinyl chloride through the addition of nanoparticulate calcium carbonate显示文摘 | Kemal I Whittle A Burford R | 2009 | Polymer2009,50,: | 1 |
| 15 | Toughening of unmodified polyvinylchloride through the addition of nanoparticulate calcium carbonate显示文摘 | Kemal I Whittle A Burford R | 2009 | Polymer2009,50,16: | 1 |
| 16 | A new classification scheme of plastic wastes based upon recycling labels 显示文摘 | KEMAL O SEMIH E AHIN I | 2015 | Waste Management2015,35,1: | 1 |
| 17 | Duodenum-preserving local excision of a gastrointestinal stromal tumor显示文摘BACKGROUND:Duodenal gastrointestinal stromal tumors (GISTs) are rare. Because of the complex anatomy of the duodenum, the methods of resection of these tumors are controversial and diverse. METHODS:We report a case of a duodenal GIST in the anterolateral wall of the second part of the duodenum, which was successfully managed by local excision. The surgery was facilitated by preoperative mapping with Indian ink and navigation by endoscopy to assess the adequacy of resection and to avoid injury to the ampulla. RESULT:Reconstruction was successful with a duodeno-jejunostomy and protected by a nasoduodenal drain. CONCLUSION:The patient had no postoperative complications and the tumor was confirmed to be a GIST of the duodenum successful with an adequate resection margin. | Chandika AH Liyanage Sanjaya Abeygunawardhana Sumudu Kumarage Kemal I Deen | 2008 | Hepatobiliary & Pancreatic Diseases International2008,7,2: | 1 |
| 18 | Elevated serum neu- trophil to lymphocyte and platelet to lymphocyte rati- os could be useful in lung cancer diagnosis 显示文摘 | Kemal Y Yucel I Ekiz K | 2014 | Asian Pac J Cancer Prey2014,15,6: | 1 |
| 19 | Elevated serum neutrophil to lymphocyte and platelet to lymphocyte ratios could be useful in lung cancer diagnosis显示文摘 | Kemal Y Yucel I Ekiz K | 2014 | Asian Pac J Cancer Prev2014,15,6: | 1 |
| 20 | Toughening of Un-modified Polyvinylchloride Through the Addition of Nano-particulate Calcium Carbonate 显示文摘 | Kemal I Whittle A Burford R | 2009 | Polymer2009,50,16: | 1 |