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| 1 | Erythropoietin therapy after out-of-hospital cardiac arrest:A systematic review and meta-analysis显示文摘AIM To assess safety and efficacy of early erythropoietin(Epo) administration in patients with out-of-hospital cardiac arrest(OHCA).METHODS A systematic literature search was performed using PubM ed,MEDLINE,EMBASE,EBSCO,CINAHL,Web of Science and Cochrane databases,of all studies published from the inception through October 10,2016.Inclusion criteria included:(1) Adult humans with OHCA and successful sustained return of spontaneous circulation;and(2) studies including mortality/brain death,acute thrombotic events as their end points.Primary efficacyoutcome was 'brain death or Cerebral Performance Category(CPC) score of 5'.Secondary outcomes were 'CPC score 1,and 2-4','overall thrombotic events' and 'acute coronary stent thrombosis'.RESULTS We analyzed a total of 606 participants(n = 276 received Epo and n = 330 with standard of care alone) who experienced OHCA enrolled in 3 clinical trials.No significant difference was observed between the Epo and no Epo group in brain death or CPC score 5(OR = 0.77;95%CI:0.42-1.39),CPC score 1(OR = 1.16,95%CI:0.82-1.64),and CPC score 2-4(OR = 0.77,95%CI:0.44-1.36).Epo group was associated with increased thrombotic complications(OR = 2.41,95%CI:1.26-4.62) and acute coronary stent thrombosis(OR = 8.16,95%CI:1.39-47.99).No publication bias was observed.CONCLUSION Our study demonstrates no improvement in neurological outcomes and increased incidence of thrombotic events and acute coronary stent thrombosis in OHCA patients who were treated with Epo in addition to standard therapy. | Rahul Chaudhary Jalaj Garg Parasuram Krishnamoorthy Kevin Bliden Neeraj Shah Nayan Agarwal Rahul Gupta Abhishek Sharma Karl B Kern Nainesh C Patel Paul Gurbel | 2017 | World Journal of Cardiology2017，9，12： | 2 |
| 2 | Early results of the Swiss multicentre bypass or sleeve study (SM-BOSS): a prospective randomized trial comparing laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass 显示文摘 | Peterli R Borbely Y Kern B | 2013 | Ann Surg2013，258，5： | 1 |
| 3 | Cbfα1 contributes to the osteoblast--specific expression of type Ⅰ collagen genes 显示文摘 | Kern B Shen J Starbuck M | 2001 | J Biol Chem2001，276，10： | 1 |
| 4 | swallow-related cerebra cortical activity maps are not specific to deglutition显示文摘 | Rasmus B Jaradeh S | 2001 | Am J Physiol Gasrointest Liver Physiol2001，280，： | 1 |
| 5 | An open-label Comparison of the neurocognitive effects of aripiprazole vs olanzapine in patients with stable psychosis显示文摘 | Kern RS Cornblatt B Carson WH | 2004 | Schizophr Res2004，，： | 1 |
| 6 | Stress and fold localization in thin e lastic membranes 显示文摘 | Pocivavsek L Dellsy R Kern A Johnson S Lin B Lee KY C Cerda E | 2008 | Science2008，320，： | 1 |
| 7 | Computer Modelling for the Prediction of Microstructure Development and Mechanical Properties of HSLA Steel Plates 显示文摘 | Kern A Degenkolbe J Musgen B | 1992 | ISIJ1992，32，3： | 1 |
| 8 | The diagnosis and incidence of allergic fungal sinusitis显示文摘 | PONIKAU J U SHERRIS D A KERN E B | 1999 | Mayo Clin Proc1999，74，： | 1 |
| 9 | End- tidal Carbon dioxide monitoring during cardiopulmonary re- suscitation显示文摘 | SANDERS A B KERN K B CHARLES M D | 1989 | JAMA1989，262，： | 1 |
| 10 | Control of microrna-21 expression in colorectal cancer cells by oncogenic epidermal growth factor/ras signaling and its transcription factors 显示文摘 | Kern H B Niemeyer B F Parrish J K | 2012 | DNA Cell Biol2012，31，8： | 1 |
| 11 | Erosion iinvestigation and sediment quality measurements for a comprehensive risk assessment of con- taminated aquatic sediments 显示文摘 | Haag I Kern U Westrich B | 2001 | Science of the Total Environ ment2001，，266： | 1 |
| 12 | The Single-period Inventory Problem: Ex-tension to Random Yield From the Perspective of theSupply Chain显示文摘 | KERN B | 2009 | Omega2009，37，4： | 1 |
| 13 | Fewer nutrient deficiencies after laparoscopic sleeve gastrectomy(LSG)than after laparoscopic Roux-Y-gastric bypass(LRYGB)-a prospective study显示文摘 | Gehrer S Kern B Peters T | 2010 | Obes Surg2010，20，4： | 1 |
| 14 | A twist code determines the onset of osteoblast differentiation显示文摘 | Bialek P Kern B Yang X | 2004 | Dev Cell2004，6，3： | 1 |
| 15 | C erbB 2 expression in breast cancer detected by immunoblotting and immunohistochemistry 显示文摘 | Kerns B J M Pence J C Huper G etal | 1990 | Histochem Cytochem1990，38，： | 1 |
| 16 | Genetic alterations during colorectal-tumor development显示文摘 | Vogelstein B Fearon ER Hamilton SR Kern SE Preisinger AC Leppert M Nakamura Y White R Smits AM Bos JL | 1988 | N Engl J Med1988，319，9： | 1 |
| 17 | Large-scaledelineation of secreted protein biomarkers overexpressed in cancertissue and serum显示文摘 | WELSH J B SAPINOSO L M KERN S G | 2003 | Proc Natl Acad Sci U S A2003，100，6： | 1 |
| 18 | Purification, eharaeterisationand erystallisation of photosystem Ⅱ from Thermosynechococcus elongatus cultivated in a new type of photobioreaetor显示文摘 | Kern J Loll B Luneberg C | 2005 | Biochimica et Biophysica Acta (BBA) - Bioenergetics2005，1706，： | 1 |
| 19 | Season and severity of prescribed burn in ponderosa pine forests:implications for understory native and exotic plants显示文摘 | Kerns B K Thies W G Niwa C G | 2006 | Ecoscience2006，13，1： | 1 |
| 20 | Lipids in photosystem II: interactions with protein and cofactors显示文摘 | Loll B Kern J Saenger W Zouni A Biesiadka J | 2007 | Biochim Biophys Acta2007，1767，6： | 1 |
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