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| 1 | Is rectal indomethacin effective in preventing of post-endoscopic retrograde cholangiopancreatography pancreatitis?显示文摘AIM:To investigate the effectiveness of rectally administered indomethacin in the prophylaxis of post-endoscopic retrograde cholangiopancreatography(ERCP)pancreatitis and hyperamylasaemia in a multicentre study.METHODS:A prospective,randomised,placebocontrolled multicentre study in five endoscopic units was conducted on 686 patients randomised to receive a suppository containing 100 mg indomethacin,or an inert placebo,10-15 min before ERCP.Post-ERCP pancreatitis and hyperamylasaemia were evaluated 24 h following the procedure on the basis of clinical signs and laboratory parameters,and computed tomography/magnetic resonance imaging findings if required.RESULTS:Twenty-one patients were excluded because of incompleteness of their data or because of protocol violation.The results of 665 investigations were evaluated:347 in the indomethacin group and 318 in the placebo group.The distributions of the risk factors in the two groups did not differ significantly.Pancreatitis developed in 42 patients(6.3%):it was mild in34(5.1%)and severe in eight(1.2%)cases.Hyperamylaesemia occurred in 160 patients(24.1%).There was no significant difference between the indomethacin and placebo groups in the incidence of either postERCP pancreatitis(5.8%vs 6.9%)or hyperamylasaemia(23.3%vs 24.8%).Similarly,subgroup analysis did not reveal any significant differences between the two groups.CONCLUSION:100 mg rectal indomethacin administered before ERCP did not prove effective in preventing post-ERCP pancreatitis. | Zoltán Dbrnte Zoltán Szepes Ferenc Izbéki Judit Gervain László Lakatos Gyula Pécsi Miklós Ihász Lilla Lakner Erzsébet Toldy László Czakó | 2014 | World Journal of Gastroenterology2014，20，29： | 16 |
| 2 | Synchronous electrogastrographic and manometric study of the stomach as an esophageal substitute显示文摘AIM: To investigate the electric and contractile mechanisms involved in the deranged function of the transposed stomach in relation to the course of the symptoms and the changes in contractile and electrical parameters over time.METHODS: Twenty-one patients after subtotal esophagectomy and 18 healthy volunteers were studied.Complaints were compiled by using a questionnaire, and a symptom score was formed. Synchronous electrogastrography and gastric manometry were performed in the fasting state and postprandially.RESULTS: Eight of the operated patients were symptomfree and 13 had symptoms. The durations of the postoperative periods for the symptomatic (9.1±6.5 mo)and the asymptomatic (28.3±8.8 mo) patients were significantly different. The symptom score correlated negatively with the time that had elapsed since the operation. The percentages of the dominant frequency in the normogastric, bradygastric and tachygastric ranges differed significantly between the controls and the patients.A significant difference was detected between the power ratio of the controls and that of the patients. The occurrence of tachygastria in the symptomatic and the symptom-free patients correlated negatively both with the time that had elapsed and with the symptom score. There was a significant increase in motility index after feeding in the controls, but not in the patients. The contractile activity of the stomach increased both in the controls and in the symptom-free patients. In contrast, in the group of symptomatic patients, the contractile activity decreased postprandially as compared with the fasting state.CONCLUSION: The patients' post-operative complaints and symptoms change during the post-operative period and correlate with the parameters of the myoelectric and contractile activities of the stomach. Tachygastria seems to be the major pathogenetic factor involved in the contractile dysfunction. | Ferenc Izbéki Tibor Wittmann Sándor (O|')dor Balázs Botos (A|')ron Altorjay | 2005 | World Journal of Gastroenterology2005，11，8： | 2 |
| 3 | 无机硒和有机硒对羊瘤胃内容物的脂肪酸组成、瘤胃细菌和纤毛虫的影响显示文摘试验旨在研究3个月每天等摩尔饲喂有机硒和无机硒对瘤胃内容物脂肪酸组成、瘤胃细菌和原生动物的影响。12只羊饲喂含有干草1 380 g·只-1DM和大麦450 g·只-1DM的基础日粮,基础日粮中含硒0.16 mg·kg-1DM。将羊随机分成3组,包括饲喂基础日粮(对照组)、在基础日粮中添加无机硒0.4 mg·kg-1DM(Na2SeO3,ISe)、在基础日粮中添加有机硒0.4mg·kg-1DM(酵母硒,OSE)。测定瘤胃内容物(TRC)中脂肪酸(FA)含量、细菌数(BF)和纤毛原虫数(PF)。OSe组的TRC中C18:2cis-9,trans-11的含量显著降低(P<0.05),α-亚麻酸浓度(C18:3 N 3;LNA)极显著增加(P<0.01)。ISe组BF中肉豆蔻酸(C14:0;P<0.05)、棕榈酸(P<0.01)和中链脂肪酸(P<0.01)含量下降,长链脂肪酸(P<0.05)、硬脂酸(C18:0,P<0.01)、花生酸(C20:0,P<0.001)和山嵛酸(C22:0,P<0.01)含量升高。OSe组BF的辛酸(C8:0,P<0.001)、二十碳四烯酸(C20:4 n6,P<0.01)、二十碳三烯酸(C20:3 n3,P<0.01)浓度增加。ISe组PF的十二碳六烯酸(C22:6 n3)和tricosylic酸(C23:0,P<0.05)含量下降。添加OSe可以增加LNA的含量(P<0.01),降低棕榈油酸的含量(C16:1,P<0.05)。结果表明,饲粮中添加OSe可以通过瘤胃微生物影响多不饱和脂肪酸(PUFA)含量,特别是瘤胃纤毛虫,使多不饱和脂肪酸氢化成更饱和脂肪酸。 | Kiidayová S Mihaliková K Siroka P Cobanová K Váradyová Z | 2014 | 饲料博览2014，0，9： | 2 |
| 4 | Solution structure of the epithelial cadherin domain responsible for selective cell adhesion显示文摘 | Overduin M Harvey TS Bagby S Tong KI Yau P Takeichi M Ikura M | | 0，，： | 2 |
| 5 | Increased prevalence of intestinal inflammation in patients with liver cirrhosis显示文摘AIM To investigate the pathophysiology of the digestive tract in patients with liver cirrhosis.METHODS In 42 cirrhotic patients and 20control subjects, the following fecal proteinswere measured by enzyme-linkedimmunosorb6nt assay: albumin (Alb ),transferrin (Tf), and al-antitrypsin (a,-AT) as amarker for intestinal protein l0ss, hemoglobin(Hb) for bleeding, PMN-eIastase for intestinalinflammation, and secretory lgA for intestinalimmunity.RESULTS The fecaI concentrations of Hb, Alb,Tf, al-AT, and PMN’eIastase were increased in13 (3l%), 8(19%), l0(24%), 6(14%), and 1l(26%) cases among 42 patients, resPectiveIy.F6cal concentration of secretory IgA wasdecreased in 7 (l7%) of 42 patients. However,these fecal concentrations were not related tothe severity or etiology of liver cirrhosis. Theserum Alb level was significantIy decreased inpatients with intestinal protein Ioss c0mpared tothat in patients without intestinal protein loss.CONCLUSION These findings suggest that: rob6sides the weIl’known pathological conditions,Such as bleeding and protein loss, intestinaIinflammati0n and decreased intestinaI immunityare found in cirrhotic patients, @ intestinalprotein loss contributes to hypoalbuminemia incirrhotic patients, and @ intestinaI inflammationshouId not b6 0verlooked in cirrhotic patients,since it may contribute to or cause intestinalprotein Ioss and oth6r various pathologicalconditions. | Saitoh O Sugi K Lojima K Matsumoto H Nakagawa K Kayazawa M Tanaka S Teranishi T Hirata I Katsu Ki K | 1999 | World Journal of Gastroenterology1999，5，5： | 2 |
| 6 | A Muhicentre evaluation of the Medtronic AVE flexible Iliac Bridge stent in the iliac arteries (the first study) 显示文摘 | Gaines PA Schuhe KI Muller-Hulsbeck S | 2005 | Eur J Vasc Endovasc Surg2005，29，2： | 1 |
| 7 | Evaporator models for operation with dry,wet and frosted finned surfaces显示文摘 | Oskarsson SP Krakow KI Lin S | 1990 | ASHRAE Transactions1990，96，1： | 1 |
| 8 | Synthesis and biological properties of new 1-methylcarbapenms having tetrazolothioether moiety显示文摘 | Kye J S Ki D K | 2000 | Bioorg Med Chem Lett2000，56，36： | 1 |
| 9 | The association of metabolic syndrome with adipose tissue hormones and insulin resistance in patients with COPD without co- morbidities显示文摘 | Minas M Kostikas K Papaioannou AI Mystridou P Karetsi E Georgoulias P Liakos N Pournaras S Gourgoulianis KI | 2011 | COPD2011，8，6： | 1 |
| 10 | An integrated one-cycle control buck converter with adaptive output and dual loops for output error correction显示文摘 | Ma D S Ki W H Tsui C Y | 2004 | IEEE Journal of Solid-State Circuits2004，39，1： | 1 |
| 11 | Correlation between FDG uptake by PET/CT and the expressions of glucose transport- er type I and hexokinase II in cervical cancer显示文摘 | Tong S Y Lee J M Ki K D | 2012 | Internation- al Journal of Gynecological Cancer2012，22，4： | 1 |
| 12 | Physicochemical properties of different types of starch phosphate monoesters 显示文摘 | Mahmoud Z Sitohy Said S KI - Saadony | 2000 | Starch/Starke2000，52，4： | 1 |
| 13 | Patient characteristics and risk of subsequent contralateral hip fracture after surgical management of first fracture显示文摘 | Jeffrey C Ki W H Shahzad S | 2014 | Injury2014，45，10： | 1 |
| 14 | Probiotics in primary prevention of atopic disease:a randomised placebo-controlled trial显示文摘 | KALLIOMKI M SALMINEN S ARVILOMMI H | 2001 | The Lancet2001，357，9262： | 1 |
| 15 | Factors dominating stratification cycle and seasonal water quality variation in a Korean estuarine reservoir显示文摘 | Lee Y G Kang J H Ki S J | 2010 | Journal of Environmental Monitoring2010，12，5： | 1 |
| 16 | 显示文摘 | Kim S Ki JY Lee TH | 2002 | Autoimmunity2002，35，1： | 1 |
| 17 | Endothelin in receptor subtypes in resistance arteries from human and rats显示文摘 | Deng LY Ki J S Schiffrin E L | 1995 | Cardiovas Res1995，29，： | 1 |
| 18 | Effect of phytase supplementation to diets for weanling pigs on the digestibilities of chide proteins,amino acids,and energy显示文摘 | Liao S F Sauer W C Kies A K | 2005 | J Anim Sci2005，83，： | 1 |
| 19 | Approach to functional safety-compliant ECU design for electro-mechanical brake systems显示文摘 | Lee K J Ki Y H Cheon J S | 2014 | International Journal of Automotive Technology2014，15，2： | 1 |
| 20 | Mode of delivery-effects on gut microbiota and humoral immunity显示文摘 | Huurre A Kalliomki M Rautava S | 2008 | Neonatology2008，93，4： | 1 |
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