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| 1 | Effect of Powder Particle Shape on the Properties of In Situ Ti–TiB Composite Materials Produced by Selective Laser Melting显示文摘This work studied the preparation of starting powder mixture influenced by milling time and its effect on the particle morphology(especially the shape) and, consequently, density and compression properties of in situ Ti–Ti B composite materials produced by selective laser melting(SLM) technology. Starting powder composite system was prepared by mixing 95 wt% commercially pure titanium(CP-Ti) and 5wt% titanium diboride(TiB 2) powders and subsequently milled for two different times(i.e. 2 h and 4 h).The milled powder mixtures after 2 h and 4 h show nearly spherical and irregular shape, respectively.Subsequently, the resultant Ti–5 wt% TiB 2 powder mixtures were used for SLM processing. Scanning electron microscopy image of the SLM-processed Ti–Ti B composite samples show needle-shape TiB phase distributed across the Ti matrix, which is the product of an in-situ chemical reaction between Ti and TiB 2during SLM. The Ti–Ti B composite samples prepared from 2 h and 4 h milled Ti–TiB 2 powders show different relative densities of 99.5% and 95.1%, respectively. Also, the compression properties such as ultimate strength and compression strain for the 99.5% dense composite samples is 1421 MPa and 17.8%, respectively, which are superior to those(883 MPa and 5.5%, respectively) for the 95.1% dense sample. The results indicate that once Ti and TiB 2 powders are connected firmly to each other and powder mixture of nearly spherical shape is obtained, there is no additional benefit in increasing the milling time and, instead, it has a negative effect on the density(i.e. increasing porosity level) of the Ti–Ti B composite materials and their mechanical properties. | Hooyar Attar Konda G.Prashanth Lai-Chang Zhang Mariana Calin Ilya V.Okulov Sergio Scudino Chao Yang Jürgen Eckert | 2015 | Journal of Materials Science & Technology2015，31，10： | 12 |
| 2 | Colon cancer and the epidermal growth factor receptor:Current treatment paradigms,the importance of diet,and the role of chemoprevention显示文摘Colorectal cancer represents the third most common and the second deadliest type of cancer for both men and women in the United States claiming over 50000 lives in 2014. The 5-year survival rate for patients diagnosed with metastatic colon and rectal cancer is < 15%. Early detection and more effective treatments are urgently needed to reduce morbidity and mortality of patients afflicted with this disease. Here we will review the risk factors and current treatment paradigms for colorectal cancer, with an emphasis on the role of chemoprevention as they relate to epidermal growth factor receptor(EGFR) blockade. We will discuss how various EGFR ligands are upregulated in the presence of Western diets high in saturated and N-6 polyunsaturated fats. We will also outline the various mechanisms of EGFR inhibition that are induced by naturally occurring chemopreventative agents such as ginseng, green tea, and curcumin. Finally, we will discuss the current role of targeted chemotherapy in colon cancer and outline the limitations of our current treatment options, describing mechanisms of resistance and escape. | Baldeep Pabla Marc Bissonnette Vani J Konda | 2015 | World Journal of Clinical Oncology2015，6，5： | 7 |
| 3 | Humanized antibody directed to the IL-2 receptor beta-chain prolongs primate cardiac allograft surrival 显示文摘 | Tinubu SA Hakimi J kondas JA | 1994 | Immunol1994，153，： | 1 |
| 4 | Early diagnosis and management of esophageal and gastric cancer显示文摘 | Lang G D Konda V J | 2013 | Minerva Gastroenterol Dietol2013，59，13： | 1 |
| 5 | The alpha subunit of the human IgE receptor(FccR I ) is sufficient for high affinity IgE binding显示文摘 | Hakimi J Seals C Kondas JA | 1990 | J Biol Chem1990，265，22： | 1 |
| 6 | Complete Barrett's eradication endoscopic mucosal resection:an effective treatment modality for high-grade dysplasia and intramucosal carcinoma-an American single-center experience显示文摘 | Chennat J Konda VJ Ross AS | 2009 | Am J Gastroenterol2009，104，11： | 1 |
| 7 | Early diagnosis and management of esophageal and gastric cancer显示文摘 | Lang G D Konda V J | 2013 | Minerva Gastroenterol Dietol2013，59，4： | 1 |
| 8 | Extraction of copper,zinc,nickel and cobalt in acid oxidative leaching of chalcopyrite at the presence of deep-sea manganese nodule as oxidant显示文摘 | HAVLIK T LAUBERTOVA M MISKUFOVA A KONDAS J VRANKA F | 2005 | Hydrometallurgy2005，77，： | 1 |
| 9 | Brain-specific angio- genesis inhibitor 1 is a putative factor for inhibition of neovascular formation in renal cell carcinoma 显示文摘 | IZUTSU T KONDA R SUGIMURA J | 2011 | The Journal of Urology2011，185，： | 1 |
| 10 | The α subunit of the hu man IgE receptor(FcεRI) is sufficient for high affinity IgE binding显示文摘 | Seals C Kondas JA | 1990 | J Bio Chem1990，265，22： | 1 |
| 11 | Seasonal frost depth of grounds with the bare surface,snow cover and vegetation显示文摘 | Yamazaki T Nishida A Konda J | 1998 | Journal of the Japanese Society of Snow and Ice1998，60，3： | 1 |
| 12 | Clinical significance of urinary interleukin-6 in children with reflux nephropathy显示文摘 | Konda R Sato H | 2001 | J Urol2001，165，： | 1 |
| 13 | Prediction of ground deformation due to shield excavation in clayey soils显示文摘 | HASHIMOTO T NAGAYA J KONDA T | 1999 | Soils and Foundations1999，39，3： | 1 |
| 14 | Splenic injury: a rare com- plication of percutaneous nephrolithotomy显示文摘 | Kondas J Szentgyorgyi E V6czi L | 1994 | Int Urol Nephrol1994，26，4： | 1 |
| 15 | Interaction of dual in- traceUular signaling pathways activated by the melano- cortin-3 receptor显示文摘 | Konda Y Gantz I DelValle J | 1994 | J Biol Chem1994，269，13： | 1 |
| 16 | Confocal laser endomicroscopy: potential in the management of Barrett's esophagus 显示文摘 | Konda VJ Chennat JS Hart J | 2010 | Dis Esophagus2010，23，5： | 1 |
| 17 | Transurethral resection for muscle invasive bladder cancer显示文摘 | Kondas J Vaczi L Szecso L | 1993 | Int Urol Nephrol1993，25，5： | 1 |
| 18 | Problem drinking is as- sociated with increased prevalence of sexual risk behaviors among men who have sex with men (MSM) in Lima, Peru显示文摘 | DEISS R G CLARK J L KONDA K A | 2013 | Drug Alcohol De- pend2013，132，12： | 1 |
| 19 | Interaction of dual intracellular signaling pathways activated by the melanocortin-3 receptor 显示文摘 | KONDA Y GANTZ I DELVALLE J | 1994 | Biol Chem1994，269，13： | 1 |
| 20 | On actor-critic algorithms显示文摘 | Konda V R Tsitsiklis J N | 2003 | SIAM Journal on Control Optim2003，42，4： | 1 |
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