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| 1 | 微酸性电解水的研究与应用展望显示文摘微酸性电解水pH值在5.0~6.5之间,呈微酸性,对绝大多数细菌以及病毒都有显著杀菌效果,且对人体无害。该文结合笔者实验研究综述了微酸性电解水在食品加工及保鲜、医疗以及农业领域等方面的研究现状与应用前景。 | 梁永娅 余晓青 Kurahashi Midori 丁林贤 | 2012 | 科技创新导报2012，9，34： | 11 |
| 2 | Oxidative stress as a potential causal factor for autoimmune hemolytic anemia and systemic lupus erythematosus显示文摘The kidneys and the blood system mutually exert influence in maintaining homeostasis in the body. Because the kidneys control erythropoiesis by producing erythropoietin and by supporting hematopoiesis, anemia is associated with kidney diseases. Anemia is the most prevalent genetic disorder, and it is caused by a deficiency of glucose 6-phosphate dehydrogenase(G6PD), for which sulfhydryl oxidation due to an insufficient supply of NADPH is a likely direct cause. Elevated reactive oxygen species(ROS) result in the sulfhydryl oxidation and hence are another potential cause for anemia. ROS are elevated in red blood cells(RBCs) under superoxide dismutase(SOD1) deficiency in C57BL/6 mice. SOD1 deficient mice exhibit characteristics similar to autoimmune hemolytic anemia(AIHA) and systemic lupus erythematosus(SLE) at the gerontic stage. An examination of AIHA-prone New Zealand Black(NZB) mice, which have normal SOD1 and G6 PD genes, indicated that ROS levels in RBCs are originally high and further elevated during aging. Transgenic overexpression of human SOD1 in erythroid cells effectively suppresses ROS elevation and ameliorates AIHA symptoms such as elevated anti-RBC antibodies and premature death in NZB mice. These results support the hypothesis that names oxidative stress as a risk factor for AIHA and other autoimmune diseases such as SLE. Herein we discuss the association between oxidative stress and SLE pathogenesis based mainly on the genetic and phenotypic characteristics of NZB and New Zealand white mice and provide insight into the mechanism of SLE pathogenesis. | Junichi Fujii Toshihiro Kurahashi Tasuku Konno Takujiro Homma Yoshihito Iuchi | 2015 | World Journal of Nephrology2015，4，2： | 7 |
| 3 | Platelet‐derived growth factor receptor α‐positive cells in the tunica muscularis of human colon显示文摘 | Masaaki Kurahashi Yasuko Nakano Grant W. Hennig Sean M. Ward Kenton M. Sanders | 2012 | J. Cell. Mol. Med2012，，7： | 2 |
| 4 | Laboratory simulation of space weathering-ESR measurements of nanophase metallic iron in laser-irradiated materials 显示文摘 | Kurahashi E Yamanaka C Nakamura K | 2002 | Earth Planetary Space2002，54，： | 1 |
| 5 | Long-term complete response to very-low-dose interleukin-2 thera- py in patients with metastatic renal cell carcinoma: report of two cases显示文摘 | Harada K Miyake H Kurahashi T | 2011 | Clin Exp Nephrol2011，15，6： | 1 |
| 6 | Induction of osteoblast differentiation indices by statins in MC3T3-E1 cells显示文摘 | Maeda T Matsunuma A Kurahashi I | 2004 | J Cell Bioehem2004，92，3： | 1 |
| 7 | Isolation and characterization of ovokinin, a bradykinin B 1 agonist peptide derived from ovalbumin 显示文摘 | FUJITA H USUI H KURAHASHI K | 1995 | Peptides1995，16，5： | 1 |
| 8 | The mode of vasoinhibitory action of a pyridazinone derivative (MCI-154),a new cardiotonic agent,on contractile responses induced by alpha-adrenoceptor agonists and ^45Ca influx in isolated vascular smooth muscles显示文摘 | Shibata S Satake N Hester RK Kurahashi K Ito M | 1988 | Eur J Pharmacol1988，145，2： | 1 |
| 9 | Evaluation of antimicrobial and lipopolysaccharide-neutralizing effects of a synthetic CAP18 fragment against Pseudomonas aeruginosa in a mouse model显示文摘 | SAWA T KURAHASHI K OHARA M | 1998 | Antimicrob Agents Chemother1998，42，12： | 1 |
| 10 | Induction of osteoblast differentiation indices by statins in MC3T3-E1 cells显示文摘 | Maeda T Matsunuma A Kurahashi I | | 0，，3： | 1 |
| 11 | Isolation and characterization of ovokinin, a bradykinin B1 agonist peptide derived from ovalbumin显示文摘 | FUJITA H USUI H KURAHASHI K et a1 | 1995 | Peptides1995，16，5： | 1 |
| 12 | Difficulty of peripheral blood stem cell collection after multiple consolidation therapy in acute myeloid leukaemia显示文摘 | Narimatsu H Yamamoto F Kurahashi S etal | 2008 | J Clin Exp Hematol2008，48，： | 1 |
| 13 | Atorvastatin enhances bone density in ovariectomized rats given 17beta-estradiol or human parathyroid hormone(1-34)显示文摘 | Kawane T Terashima S Kurahashi I | 2004 | Endocrine2004，24，2： | 1 |
| 14 | Chaos in a hydraulic control valve显示文摘 | Hayashi S Hayase T Kurahashi T | 1997 | Journal of Fluids and Structures1997，11，： | 1 |
| 15 | Expression of the secreted form of clusterin protein in renal cell carcinoma as a predictor of disease extension显示文摘 | Kurahashi T Muramaki M Yamanaka K | | 0，，06： | 1 |
| 16 | Long-term conservation of Diospyros germplasm using dormant buds by a prefreezing method 显示文摘 | Matsumoto T Kurahashi T Niino T | 2004 | Plant Biotechnol2004，21，： | 1 |
| 17 | Maternal genetic polymorphisms in CYP1A1, GSTM1 and GSTT1 and the risk of hypospadias显示文摘 | Kurahashi N Sara F Kasai S | 2005 | Mol Hum Reprod2005，11，2： | 1 |
| 18 | Long AT-rich palindromes and the constitutional t(11 ;22)breakpoint显示文摘 | Kurahashi H Emanuel B S | 2001 | Hum Mol Genet2001，10，23： | 1 |
| 19 | A new enzymatic defect ofgalactose metabolism in Escherichia coli K-12 mutants显示文摘 | FUKASAWA T KOKURA K KURAHASHI K | 1962 | Biochem Bio-phys Res Commun1962，7，： | 1 |
| 20 | Isolation and characterization of ovokinin, a bradykinin B1 agonist peptide derived from ovalbumin 显示文摘 | FUJITA H USUI H KURAHASHI K | 1995 | Peptides1995，16，5： | 1 |
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