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| 1 | Presence of Porphyromonas gingivalis in gingival squamous cell carcinoma显示文摘Periodontal disease has been recently linked to a variety of systemic conditions such as diabetes, cardio-vascular disease, preterm delivery, and oral cancer. The most common bacteria associated with periodontal disease, Porphyromonas gingivalis (P. gingivalis) has not yet been studied in the malignant gingival tissues. The objective of this study was to investigate the presence of P. gingivalis in specimens from squamous cell carcinoma patients. We have performed immunohistochemical staining to investigate the presence of P. gingivalis and Streptococcus gordonii (S. gordonii), a non invasive oral bacteria, in paraffin embedded samples of gingival squamous cell carcinoma (n=10) and normal gingiva (n=5). Staining for P. gingivalis revealed the presence of the bacteria in normal gingival tissues and gingival carcinoma, with higher levels (more than 33%, P<0.05) detected in the carcinoma samples. The staining intensity was also significantly enhanced in the malignant tissue by 2 folds (P<0.023) compared to specimens stained for the non-invasive S. gordonii. P. gingivalis is abundantly present in malignant oral epithelium suggesting a potential association of the bacteria with gingival squamous cell carcinoma. | Joseph Katz Mairelys D. Onate Kaleb M. Pauley Indraneel Bhattacharyya Seunghee Cha | 2011 | International Journal of Oral Science2011，3，4： | 19 |
| 2 | Maple phylogeny and biogeography inferred from phylogenomic data显示文摘Acer(the maple genus)is one of the diverse tree genera in the Northern Hemisphere with about 152 species,most of which are in eastern Asia.There are roughly a dozen species in Europe/western Asia and a dozen in North America.Several phylogenetic studies of Acer have been conducted since 1998,but none have provided a satisfactory resolution for basal relationships among sections of Acer.Here we report the first well-resolved phylogeny of Acer based on DNA sequences of over 500 nuclear loci generated using the anchored hybrid enrichment method and explore the implications of the robust phylogeny for Acer systematics and biogeography.Our phylogenetic results support the most recent taxonomic treatment of Acer by de Jong with some modifications;section Pentaphylla may be expanded to include section Trifoliata,and A.yangbiense may be included in section Lithocarpa.Sections Spicata,Negundo,Arguta,and Palmata form a clade sister to the rest of the genus where sections Glabra and Parviflora comprise the first clade followed by section Macrantha,sections Ginnala,Lithocarpa,Indivisa,sections Platanoidea and Macrophylla,section Rubra,section Acer,and section Pentaphylla.Monotypic sections Glabra and Macrophylla in North America are sister to the Japanese section Parviflora and Eurasian section Platanoidea,respectively.Ancestral area inferences using statistical dispersal and vicariance analysis(S-DIVA)and dispersal and extinction cladogenesis(DEC)methods suggest that Asia might be the most likely ancestral area of Acer as proposed by Wolfe and Tanai and molecular dating using Bayesian evolutionary analysis by sampling trees(BEAST)indicate that section diversifications of Acer might have completed largely in the late Eocene and the intercontinental disjunctions of Acer between eastern Asia and eastern North America formed mostly in the Miocene. | Jianhua Li Mark Stukel Parker Bussies Kaleb Skinner Alan R.Lemmon Emily Moriarty Lemmon Kenneth Brown Airat Bekmetjev Nathan G.Swenson | 2019 | Journal of Systematics and Evolution2019，57，6： | 3 |
| 3 | Intergrating the 'new' with the 'traditional': an innovative education model 显示文摘 | Pereira J Murzyn T Kalebic T | 2001 | J Palliate Med2001，4，1： | 1 |
| 4 | Bone sialoprotein is predictive of bone metastases in resectable non-small-cell lung cancer: a retrospective case-control study 显示文摘 | Papotti M Kalebic T Volante M | 2006 | J Clin Oncol2006，24，30： | 1 |
| 5 | Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients显示文摘 | Kaleb MP Minoru S Annie LC | 2008 | Arthritis Research Therapy2008，10，4： | 1 |
| 6 | Epigenetic changes: potential therapeutic targets 显示文摘 | Kalebic T | 2003 | Ann N Y Acad Sci2003，983，： | 1 |
| 7 | Thea Kalebie Bone sialoprotein is predictive of bone metastases in resectable non - small - cell Lung cancer: a retrospective case - control study 显示文摘 | PAPOTTI M KALEBIC T VOLANTE M | 2006 | J Clin Oncol2006，24，30： | 1 |
| 8 | Role of the IGF-I receptor in mutagenesis and tumor promotion 显示文摘 | Blakesley VA Stannard BS Kalebic T | 1997 | Endocrinology1997，152，3： | 1 |
| 9 | In vim treatment with antibody against IGF-1 receptor suppresses growth of human rhabdomyosarcoma and down-regulates p34cdc2显示文摘 | Kalebic T Tsokos M Helman LJ | 1994 | Cancer Res1994，54，21： | 1 |
| 10 | Bone sialoprotein is predic- tive of bone metastases in resectable non-small-cell lung cancer: a retrospective case-control study 显示文摘 | Papotti M Kalebic T Volante M | 2006 | J Clin Oncol2006，24，30： | 1 |
| 11 | A study on preparation of Mo-30W alloy by aluminothermic co-reduction of mixed oxides 显示文摘 | Majumdar S Kaleb G B Sharma I G | 2005 | Journal of Alloys and Compounds2005，394，： | 1 |
| 12 | Laminin receptor on human breast carcinoma cells显示文摘 | TERRANOVA V P RAO C N KALEBIC T | 1983 | Proc Natl Acad Sci USA1983，80，5： | 1 |
| 13 | Development of multilayer oxidation resistant coatings on niobium and tantalum显示文摘 | MAJUMDARA S SENGUPTA P KALEB G B SHARMA I G | 2006 | Surface and Coatings Technology2006，200，： | 1 |
| 14 | Role of the IGF-1 receptor in mutagenesis and tumor promotion 显示文摘 | Blakesley VA Stannard BS Kalebic T | 1997 | Endocrinology1997，152，3： | 1 |
| 15 | Integrating the 'new' with the'traditional': an innovative education model 显示文摘 | Pereira J Murzyn T Kalebic T | 2001 | J Palliate Med2001，4，1： | 1 |
| 16 | Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases 显示文摘 | Sherine EG Kaleb M | 2009 | Arthritis Res Ther2009，11，： | 1 |
| 17 | Role of the IGF-1 receptor in mutagenesis and tumor promotion显示文摘 | Blakesley VA Stannard BS Kalebic T | 1997 | Endocrinology1997，152，： | 1 |
| 18 | Upregulat- ed miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients 显示文摘 | Kaleb M Pauley Minoru Satoh Annie L Chan | 2008 | Arthritis Research and Therapy2008，10，4： | 1 |
| 19 | Bone sialoprotein is predictive of bone metastases in resectable non-small-cell lung cancer : a retrospective case-control study显示文摘 | Papotti M Kalebic T Volante M | 2006 | J Clin Oncol2006，24，30： | 1 |
| 20 | Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients 显示文摘 | Kaleb MP Minoru S Annie LC | 2008 | Arthritis Res Ther2008，10，4： | 1 |
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