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| 1 | Connecting Malfunctioning Glial Cells and Brain Degenerative Disorders显示文摘The DNA damage response(DDR) is a complex biological system activated by different types of DNA damage.Mutations in certain components of the DDR machinery can lead to genomic instability disorders that culminate in tissue degeneration,premature aging,and various types of cancers.Intriguingly,malfunctioning DDR plays a role in the etiology of late onset brain degenerative disorders such as Parkinson's,Alzheimer's,and Huntington's diseases.For many years,brain degenerative disorders were thought to result from aberrant neural death.Here we discuss the evidence that supports our novel hypothesis that brain degenerative diseases involve dysfunction of glial cells(astrocytes,microglia,and oligodendrocytes).Impairment in the functionality of glial cells results in pathological neuro-glial interactions that,in turn,generate a ‘‘hostile' environment that impairs the functionality of neuronal cells.These events can lead to systematic neural demise on a scale that appears to be proportional to the severity of the neurological deficit. | Natalie Kaminsky Ofer Bihari Sivan Kanner Ari Barzilai | 2016 | Genomics, Proteomics & Bioinformatics2016，14，3： | 2 |
| 2 | Comparison of two modes of stress measurement: Daily hassles and uplifts versus major life events显示文摘 | Allen D. Kanner James C. Coyne Catherine Schaefer Richard S. Lazarus | 1981 | Journal of Behavioral Medicine1981，，1： | 2 |
| 3 | Serum S100beta: a noninvasive marker of blood-brain barrier function and brain lesions 显示文摘 | Kanner AA Marchi N Fazio V | 2003 | Cancer2003，97，11： | 1 |
| 4 | The FDA alert on suicidality and antiepileptic drugs; Fire or false alarm?显示文摘 | Hesdorffer DC Kanner AM | 2009 | Epilepsia2009，50，5： | 1 |
| 5 | Depression and epilepsy: A bidirectional relation? 显示文摘 | Kanner AM | 2011 | Epilepsia2011，52，： | 1 |
| 6 | Structural MRI changes of the brain in depres- sion显示文摘 | Kanner AM | 2004 | Clin EEG Neurosci2004，35，1： | 1 |
| 7 | Hydrogen peroxide generation in ground muscle tissues显示文摘 | HAREL S KANNER J | 1985 | Journal of Agricultural and Food Chemistry1985，33，6： | 1 |
| 8 | Serum s100beta:a noninvasive maker of blood-brain barrier function and brain lesions显示文摘 | KANNER AA MARCHI N FAZIO V | 2003 | Cancer2003，97，11： | 1 |
| 9 | Serum S100 beta:a noninvasive marker of blood-brain barrier function and brain lesion显示文摘 | Kanner AA Marchi N Fazio V | 2003 | Cancer2003，97，11： | 1 |
| 10 | Determination and involvement of aqueous in oxidative defense systems of various senscing leaves显示文摘 | Meir S Kanner J Akiri B | 1995 | Journal of Agricultural and Food Chemistry1995，，43： | 1 |
| 11 | Antioxidant and prooxidant effects of phenolics on pancreatic β-cells in vitro显示文摘 | Lapidot T Walker M D Kanner J | 2002 | J Agric Food Chem2002，50，25： | 1 |
| 12 | Depression in epilepsy: a common but often unrecognized comorbid malady 显示文摘 | KANNER AM PALAC S | 2000 | Epilepsy Behave2000，1，1： | 1 |
| 13 | Current reviewin clinical science:depressioninepilepsy:neurobiologic perspective显示文摘 | Kanner AM | 2005 | Epilepsy Curr2005，5，1： | 1 |
| 14 | Depression in epilepsy: prevalence, clinical semiology, pathogenic mechanisms, and treatment显示文摘 | v Kanner AM | 2003 | Biol Psychiatry2003，54，： | 1 |
| 15 | Serum S100 beta: a noninvasive marker of blood-brain barrier function and brain lesions 显示文摘 | Kanner AA Marchi N Fazio V | 2003 | Cancer2003，97，11： | 1 |
| 16 | Inhibition of oxidation of human low-density lipoproteins by phenolic substances in red wine显示文摘 | Kanner German | 1993 | Lancet1993，341，： | 1 |
| 17 | Purification and reconstitution of the sodium-and potassium-coupled glutamate transport glycoprotein from rat brain显示文摘 | Danbolt N C Pines G Kanner B I | 1990 | Biochemistry1990，29，28： | 1 |
| 18 | Counterflow of L-glutamate in plasma membrane vesicles and reconstituted preparations from rat brain显示文摘 | Pines G Kanner BL | 1990 | Biochemistry1990，29，11： | 1 |
| 19 | The impact of genotype on outcome in oligodendroglioma: validation of the loss of chromosome arm 1p as an important factor in clinical decision making显示文摘 | Kanner AA Staugaitis SM Castilla EA | 2006 | J Neurosurg2006，104，4： | 1 |
| 20 | Depression and epilepsy: epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrence显示文摘 | Kanner AM Schachter SC Barry J J | 2012 | Epi- lepsy Behav2012，24，2： | 1 |
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