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127篇 您的检索式:作者名="Karsdal"
    题名 作者 年代 出处 被引量
1The minor collagens in articular cartilage显示文摘关节的软骨是由统治它的湿、干燥的重量的体积的一个专业化细胞外的矩阵(ECM ) 组成的一个结缔组织。类型 II 骨胶原和 aggrecan 是在软骨的主要 ECM 蛋白质。然而,很少注意都没对不太丰富的分子的部件,特别次要的骨胶原,包括的类型 IV, VI, IX, X, XI, XII, XIII,和 XIV 被给予,等等。尽管为仅仅成熟矩阵的小部分的财务,这些次要的骨胶原不仅在关节的软骨的机械性质,组织,和形状起必要结构的作用,而且完成特定的生物功能。这些次要的骨胶原的基因研究表明了他们与多重结缔组织疾病被联系,特别退化的联合疾病。软骨的进步破坏包括这些次要的骨胶原包含矩阵成分的降级。碎裂的分子的产生和版本能与能力产生新奇生物化学的标记监视疾病前进,便于药开发并且增加存在工具箱为在 vitro 研究,现出症状之前的潜的研究和临床的试用。Yunyun Luo DovUe Sinkeviciute Yi He Morten Karsdal Yves Henrotin Ali Mobasheri Patrik Onnerfjord Anne Bay-Jensen 2017Protein & Cell2017,8,8:18
2RANKL and vascular endothelial growth factor(VEGF) induce osteoclast chemotaxis through an ERK1/2-dependent mechanism显示文摘Henriksen K Karsdal M Delaisse JM 2003J Biol Chem2003,278,48:1
3GLP-2 reduces bone resorp- tion in vitro via the osteoclast GLP-2 receptor 显示文摘Karsdal MA Holst JJ Henfiksen D 2004j Bone Miner Res2004,19,1:1
4Measure ment of a MMP 2 degraded Titin fragment in serum reflects changes in muscle turnover induced by atrophy显示文摘SUN S HEMRIKSEN K KARSDAL MA 2014Exp Geron- tol2014,58,1:1
5Calcito- nin: a drug of the past or for the future7 Physiologic inhibition of bone resorption while sustaining osteoclast numbers imp roves bone quality 显示文摘Karsdal MA Henriksen K Arnold M 2008BioDrugs2008,22,3:1
6The type I collagen frag- ments ICTP and CTX reveal distinct enzymatic pathways of bone collagen degradation显示文摘Gamero P Ferreras M Karsdal MA 2003J Bone Miner Res2003,18,5:1
7Molecular serum markers of liver fibrosis显示文摘Liu T Wang X Karsdal MA 2012Biomark Insights2012,7,:1
8Should sub- chondral bone turnover be targeted when treating osteoarthritis? 显示文摘KARSDAL M A I EEM1NG D J DAM E B 2008Osteoarthritis Cartilage2008,16,6:1
9Should subchondralbone turnover be targeted when treating osteoarthritis? 显示文摘Karsdal MA Leeming DJ Dam EB 2008Osteoarthritis and Cartilage / OARS Osteoarthritis ResearchSociety2008,16,6:1
10Matrix Metalloproteinase-dependent turnover of eartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis 显示文摘Siebuhrl AS Wang JX Karsdal M 2012J Transl Med2012,10,:1
11Matrix metalloporoteinase-dependent activation of latent transforming growth factor-beta controls the conversion of osteoblasts into osteocytes by blocking osteoblast apoptosis 显示文摘Karsdal MA Larsen L Engsing MT 2002J Biol Chem2002,277,44:1
12The extracellular matrix in the kidney:a source of novel non-invasive biomarkers of kidney fibrosis?显示文摘Manresa Diana Julie Leeming Morten Asser Karsdal 2014Fibrogenesis&Tissue Repair2014,,7:1
13Induction of increased cAMP levels in articular chondrocytes blocks matrix metalloproteinase-mediated cartilage degradation, but not aggrecanase-mediated cartilage degradation显示文摘Karsdal M A Sumer E U Wulf H 2007Arthritis Rheum2007,56,5:1
1464 Oral calcitonin dem-onstrated symptom-modifying efficacy and increased cartilage vol-ume:results irom A 2-year phase 3 trial in patients with osteoarth-ritis of the knee显示文摘Karsdal M Alexandersen P John M 2011Osteoarthritis Cartilage2011,19,:1
15The effect of oral salmon calcitonin delivered with 5-CNAC on bone and cartilage degradation in osteoarthritic patients: a 14-day randomized study显示文摘Karsdal MA Byrjalsen I Henriksen K 2010Osteoarthritis Cartilage2010,18,2:1
16The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet? 显示文摘Karsdal MA Bay-Jensen AC Henriksen K 2012Menopause Int2012,18,4:1
17The type I collagen fragments ICTP and CTX reveal distinct enzymatic pathways of bone collagen degradation显示文摘Garnero P Ferreras M Karsdal MA 2003Bone Miner Res2003,18,:1
18Increased urinary excretion of C-telopeptides of type II col agen (CTX-II) predicts cartilage loss over 21 months by MRI显示文摘Dam EB Byrjalsen I Karsdal MA 0,,03:1
19The effect of oral salmon calcitonin delivered with 5- CNAC on bone and cartilage deg- radation in osteoarthritie patients: a 14-day randomized study 显示文摘Karsdal MA Byrjalsen I Henriksen K 2010Osteoarthritis Cartilage2010,18,2:1
20Thetype I collagen fragments ICTP and CTX reyeal distinct enzymatic pathways of bone collagen degradation 显示文摘Garnero P Ferreras M Karsdal MA 2003J Bone Miner Res2003,18,:1
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