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| 1 | Systematic review of novel ablative methods in locally advanced pancreatic cancer显示文摘Unresectable locally advanced pancreatic cancer with or without metastatic disease is associated with a very poor prognosis.Current standard therapy is limited to chemotherapy or chemoradiotherapy.Few regimens have been shown to have a substantial survival advantage and novel treatment strategies are urgently needed.Thermal and laser based ablative techniques are widely used in many solid organ malignancies.Initial studies in the pancreas were associated with significant morbidity and mortality,which limited widespread adoption.Modifications to the various applications,in particular combining the techniques with high quality imaging such as computed tomography and intraoperative or endoscopic ultrasound has enabled real time treatment monitoring and significant improvements in safety.We conducted a systematic review of the litera-ture up to October 2013.Initial studies suggest that ablative therapies may confer an additional survival benefit over best supportive care but randomised studies are required to validate these findings. | Margaret G Keane Konstantinos Bramis Stephen P Pereira Giuseppe K Fusai | 2014 | World Journal of Gastroenterology2014,20,9: | 30 |
| 2 | 监督式民主:新媒体时代民主实践的新理念显示文摘本文检验了现存民主形态正在经历的历史性变革,尤其是新媒体所带来的社会环境变化对民主框架和机制的影响,从而为当代的代议民主提供一种全新的路径。结合新媒体时代中现行民主的转向,本文提出监督式民主的设想,认为该民主形态正将我们从过去以大会为基础的、代议的民主引向一种有着全然不同框架和机制的民主形式,这也是当代民主实践的重要特征。 | John Keane 吴小坤 | 2009 | 开放时代2009,,2: | 9 |
| 3 | Clinical utility of Epstein-Barr virus DNA and other liquid biopsy markers in nasopharyngeal carcinoma显示文摘Nasopharyngeal carcinoma(NPC)is a malignant epithelial tumor ubiquitously associated with the Epstein-Barr virus(EBV),which is highly prevalent in South China,Southeast Asia,and North Africa.Despite being a highly radio-sensitive and treatable cancer,a majority of NPC patients are diagnosed in their advanced stage,and locoregional and distant relapses following definitive treatment contribute largely to cancer-specific mortality among these patients.Given that EBV-driven NPC is the predominant variant seen in endemic regions,various EBV detection methods have been developed and are utilized in screening,prognostication,and post-treatment surveillance of NPC patients.While the Immunoglobulin A(IgA)serology assay is the most extensively studied EBV detection method,the detection of plasma EBV DNA released during replication or cellular apoptosis has shown superior outcomes in endemic population screening,prognostication,and detection of distant relapse.Furthermore,there is emerging evidence on the use of circulating tumor cells,microRNAs,DNA hypermethylation,and combination assays in various clinical scenarios.Herein,this paper provides a comprehensive overview of the relevant studies using various EBV detection techniques in the management of NPC.Specifically,the recent advances,clinical evidence,and challenges associated with the clinical application of EBV liquid biopsies in population screening,prognostication,and surveillance of NPC are presented. | Rong Tan Sean Kean Ann Phua Yoke Lim Soong Lynette Lin Ean Oon Kian Sing Chan Sasidharan Swarnalatha Lucky Jamie Mong Min Han Tan Chwee Ming Lim | 2020 | Cancer Communications2020,40,11: | 8 |
| 4 | Towards a Wireless Sensor Platform for Energy Efficient Building Operation显示文摘Currently, the IT-support for energy performance rating of buildings is insufficient. So-called IT-platforms often 'built' of an ad-hoc, inconsistent combination of off-the-shelf building management compo-nents, distributed data metering equipment and several monitoring software tools. A promising approach to achieve consistent, holistic performance data management is the implementation of an integrated, modular wireless sensor platform. This paper presents an approach of how wireless sensors can be seamlessly integrated into existing and future intelligent building management systems supporting improved building performance and diagnostics with an emphasis on energy management. | Karsten Menzel Dirk Pesch Brendan O'Flynn Marcus Keane Cian O'Mathuna | 2008 | Tsinghua Science and Technology2008,13,S1: | 4 |
| 5 | Atomic layer deposition enabling higher efficiency solar cells:A review显示文摘Atomic layer deposition(ALD)can synthesise materials with atomic-scale precision.The ability to tune the material composition,film thickness with excellent conformality,allow low-temperature processing,and in-situ real-time monitoring makes this technique very appealing for a wide range of applications.In this review,we focus on the application of ALD layers in a wide range of solar cells.We focus on industrial silicon,thin film,organic and quantum dot solar cells.It is shown that the merits of ALD have already been exploited in a wide range of solar cells at the lab scale and that ALD is already applied in high-volume manufacturing of silicon solar cells. | MdAnower Hossain Kean Thong Khoo Xin Cui Geedhika K Poduval Tian Zhang Xiang Li Wei Min Li Bram Hoex | 2020 | Nano Materials Science2020,2,3: | 3 |
| 6 | 站在世界之巅 日本电动汽车产业现状显示文摘在日本政府2009年度财政预算案中,经济产业省的'革新型蓄电池尖端科学基础研究事业'被列为该年度新增项目中唯一的最优先项目(S级)。S评定的理由。 | Kean | 2010 | 汽车工程学报2010,,2: | 2 |
| 7 | Decision-Making Under Uncertainty: Capturing Dynamic Brand Choice Processes in Turbulent Consumer Goods Markets显示文摘 | Tülin Erdem Michael P. Keane | 1996 | Marketing Science1996,,: | 2 |
| 8 | Surface activated carbon nanospheres for fast adsorption of silver ions from aqueous solutions显示文摘 | Xianghua Song Poernomo Gunawan Rongrong Jiang Susanna Su Jan Leong Kean Wang Rong Xu | 2011 | Journal of Hazardous Materials2011,,: | 2 |
| 9 | Biodegradation, biodistribution and toxicity of chitosan显示文摘 | T. Kean M. Thanou | 2009 | Advanced Drug Delivery Reviews2009,,1: | 2 |
| 10 | Glomerular mesangium; its function and relationship to angiotensin Ⅱ 显示文摘 | Raij L Keane WF | 1985 | Am J med1985,79,3: | 2 |
| 11 | Polymer-drug conjugates,PDEPT and PELT:basic principles for design and transfer from the laboratory to clinic 显示文摘 | Duncan R Gac-Breton S Keane R | 2001 | J Controlled Release2001,74,13: | 2 |
| 12 | MR imaging of the knee: exanole of normal anatomy and pathology 显示文摘 | Kean DM Worthington BS Preston BJ | 1983 | Br J Radiol1983,56,: | 2 |
| 13 | Bone Formation and Inflammation in Cardiac Valves显示文摘 | Emile R. Mohler Francis Gannon Carol Reynolds Robert Zimmerman Martin G. Keane Frederick S. Kaplan | 2001 | Circulation: Journal of the American Heart Association2001,,11: | 2 |
| 14 | The exploration of information therapy for autism and dementia显示文摘This article provides explanations to how distance external Qi therapy works by quoting various rigorously designed controlled experiments conducted at various parts of the world. It also introduces a new method of thera py, Information therapy that relies on the entanglement of information carried by low hissing sound playback with mp3 player to entangle with the information of subjects exhibited by the facial photo with the whole system placed in a sealed carton.Preliminary results have shown huge potential for information therapy to be applied on neurological cases, particularly on autism and dementia. | Kean Hin Ooi Pei See Sew Irma van Tuil | 2019 | Life Research2019,2,1: | 2 |
| 15 | CXC chemokines in angiogenesis related to pulmonary fibrosis显示文摘 | Strieter R M Belperio J A Keane M P | 2002 | Chest2002,122,6: | 2 |
| 16 | IFN-gammainducible protein-10 attenuates bleomycin-induced pulmonary fibrosis via inhibition of angiogenesis显示文摘 | Keane M P Wilke C A Burdick M D | 1999 | J Immunol1999,163,56: | 2 |
| 17 | 铜矿堆浸工艺显示文摘铜矿堆浸成功的关键是采用适当的各种参数,本文论述了确定最佳条件的办法,以便用于工业生产。 | J. M. Keane 陈耀远 | 1989 | 有色矿山1989,,4: | 2 |
| 18 | Chemokine signaling in inflammation显示文摘 | KEANE M P STRIETER R M | 2000 | Crit Care Med2000,28,4: | 1 |
| 19 | Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy显示文摘 | Cooper ME De Zeeuw D Keane WF Mitch WE Parving H-H | 2001 | N Engl J Med2001,345,12: | 1 |
| 20 | Turbine blade fir-tree root design optimization using intelligent CAD and finite element analysis 显示文摘 | Song W Keane A Rees J | 2002 | Computer and Structure2002,80,: | 1 |