| 1 | Analysis of Milk Tea as a New Mixed Drug Substance in China显示文摘Among the popular mixed drugs in China,the oral solution shenxianshui and the floury drug milk tea have recently emerged.In 2014,123 bags of milk tea included in 14 cases were tested qualitatively and quantitatively,and the test results provided a basis for drug detection,prosecution,and sentencing.More than two drug components were detected in milk tea,which was characterized as a fragrant beige,yellow,or brown powder.The detection rates of methylamphetamine(MA),3,4-methylenedioxymethamphetamine(MDMA),and ketamine in milk tea were 36.6%,50.4%,and 76.4%,respectively,and the concentrations of MA,MDMA,and ketamine were 0.2-5.1,3.2-30.1,and 0.8-176.3 mg/g,respectively,in quantitative testing. | Binling Zhu Liang Meng Kefang Zheng | 2017 | Journal of Forensic Science and Medicine2017，3，1： | 1 |
| 3 | Cross-species recognition and molecular basis of SARS-CoV-2 and SARS-CoV binding to ACE2s of marine animals显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has an extremely broad host range that includes hippopotami,which are phylogenetically closely related to whales.The cellular ACE2 receptor is one of the key determinants of the host range.Here,we found that from several marine mammals and hippopotami could efficiently bind to the receptor-binding domain(RBD)of both SARS-C oV and SARS-C oV-2 and facilitate the trans duction of SARS-C oV and SARS-C oV-2 pseudo viruses into ACE2-expressing cells.We further resolved the cryo-electron microscopy complex structures of the minke whale ACE2 and sea lion ACE2,respectively,bound to the RBDs,revealing that they have similar binding modes to human ACE2 when it comes to the SARS-C oV-2 RBD and SARS-C oV RBD.Our results indicate that marine mammals could potentially be new victims or virus carriers of SARS-C oV-2,which deserves further careful investigation and study.It will provide an early warning for the prospective monitoring of marine mammals. | Shihua Li Ruirui Yang Di Zhang Pu Han Zepeng Xu Qian Chen Runchu Zhao Xin Zhao Xiao Qu Anqi Zheng Liang Wang Linjie Li Yu Hu Rong Zhang Chao Su Sheng Niu Yanfang Zhang Jianxun Qi Kefang Liu Qihui Wang George F.Gao | 2022 | National Science Review2022，9，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员