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| 1 | The mechanism of neogambogic acid-induced apoptosis in human MCF-7 cells显示文摘Neogambogic 酸(NGA ) ,在 garcinia 的活跃成分,能在 anticancer 效果禁止一些稳固的肿瘤和结果的生长。我们假设那 NGA 可能为人的乳癌房间线 MCF-7 房间的增长的抑制负责。在 vitro 调查它的 anticancer 机制, MCF-7 房间与 NGA 的各种各样的集中被对待。试金显示出的 MTT (甲基 thiazolyl tetrazolum ) 的结果有 NGA 的那治疗显著地以一种剂量依赖者方式减少了 MCF-7 房间的增长。NGA 能增加 anti-apoptotic 蛋白质 Bcl-2 的表示由 mitochondrial transmembrane 损坏伴随了的 apoptosis 相关的蛋白质 FasL, caspase-3, caspase-8, caspase-9,和 Bax 和减少的表示。MCF-7 房间上的 NGA 的 antiproliferative 效果由于 Fas/FasL 和细胞色素 C 小径的 G0/G1 拘捕,增加的 apoptosis 和激活。这些结果提供重要卓见进 NGA 通过损害乳癌房间的增长的细胞、分子的机制。 | Keming Wang Yuhong Tang Ming Sun Binbin Lu Hongqin Zhu Ou Ji Qun Shen | 2011 | Acta Biochimica et Biophysica Sinica2011,43,9: | 9 |
| 2 | Catalytic oxidation of low concentration formaldehyde over Pt/TiO_(2) catalyst显示文摘Formaldehyde(HCHO) is an important indoor pollutant.Catalytic oxidize low concentration HCHO is an effective way to eliminate indoor pollution.In this study,a series of Pt/TiO_(2) catalysts are prepared by impregnation and reduced by NaBH_4.The effects of loading amount of Pt and cry stal type of TiO_(2) on the physical and chemical properties and the catalytic performance in HCHO oxidation reaction are investigated.The results show that the quantity of active site and the oxygen vacancy of catalysts increa sed with increasing Pt content,which is beneficial to promote the further performance of catalysts.Nevertheless,with the further rises of Pt content,the specific surface area further decreases,and the proportion of Pt^(2+) species on the catalyst surface which is significant to catalytic properties also decreases,causing catalytic performance decreases.Compared with the catalyst supporting on rutile,the Pt/α-TiO_(2) catalyst supporting on anatase has larger specific surface area,more Pt^(2+) phase and easier to form oxygen vacancy in the support,which cause better catalytic performance.The catalyst with Pt content of0.1 wt% and supported by anatase TiO_(2) has the best catalytic performance.The HCHO conversion efficiency reaches 98% and 100% at 50℃ and 100 ℃, and the stabilization time is longer than 140 h. | Yuan Su Keming Ji Jiayao Xun Kan Zhang Ping Liu Liang Zhao | 2021 | Chinese Journal of Chemical Engineering2021,34,1: | 6 |
| 3 | The study of methanol aromatization on transition metal modified ZSM-5 catalyst显示文摘In this article, transition metals of Cu, La and Zn were used as adjuvant to prepare modified HZSM-5 by impregnation method. The catalysts were characterized by XRD, BET, NH_3-TPD and Py-IR to reveal the microstructure and acid property. The catalysis performances of methanol aromatization of catalysts were investigated in a fixed-bed reactor. The results show that the strength and distribution of acid center of these catalysts are significantly influenced by the species of transition metal. There are more mediate strong Lewis acid center in Zn modified HZSM-5 catalyst and therefore exhibits higher selectivity to aromatic, benzene, toluene and xylenes in the MTA reaction.. | Keming Ji Jiayao Xun Ping Liu Qingwen Song Junhua Gao Kan Zhang Jingyuan Li | 2018 | Chinese Journal of Chemical Engineering2018,26,9: | 2 |
| 4 | Synthesis and characterization of BZSM-5 and its catalytic performance in the methanol to hydrocarbons reaction显示文摘Five kinds of BZSM-5 molecular sieve with different Si/B ratio and a SiZSM-5 molecular sieve were prepared by hydrothermal synthesis method followed by acid exchange and pelletization.The samples were characterized by XRD,SEM,FT-IR,ICP,low temperature N_(2) physical adsorption and desorption,NH3-TPD and Py-IR.The catalytic performance in the reaction of methanol to hydrocarbons was evaluated in the fixed bed reactor.Compared with SiZSM-5,the amount and strength of Bronsted(B)acid were enhanced by introducing skeleton boron and the activity of the catalyst was greatly improved.The characterization and evaluation results indicated that the BZSM-5 catalyst synthesized from the gel of SiO_(2)/B2 O320 with Si/B ratio 74.48 had modest acidity strength,acid amount of 0.18 mmol NH3·g^(-1) and large mesopore volume of 0.23 cm3·g^(-1).The B acid ratio was higher and the acid strength of BZSM-5 was weaker than that of AIZSM-5,which could inhibit the deep coke formation and increase the activity stability.B-2 had the best lifetime which could reach 672 h under the same evaluation reaction conditions,due to the best matching of moderate acidity and good diffusion properties. | Junhua Gao Keming Ji Hao Zhou Jiayao Xun Zenghou Liu Kan Zhang Ping Liu | 2021 | Chinese Journal of Chemical Engineering2021,34,7: | 2 |