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| 1 | CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath显示文摘钙绑定酷氨酸调整 phosphorylation 的蛋白质(CABYR ) 是高度多态的钙绑定 tyrosine-/threonine-phosphorylated 和 serine-/threonine-phosphorylated 涉及 capacitation 的含纤维的鞘(FS ) 蛋白质。一个通常认为的领域(氨基酸 12 鈥 ? 8 ) 对类型 II 营地依赖者蛋白质 kinase A (RII ) dimerisation 和抛锚 kinase 蛋白质(AKAP ) 的规章的子单元相应在 N 终点的蛋白质 kinase A 的有约束力的领域建议那 CABYR 可以自我装配并且绑在 AKAP。而且,有证据, CABYR 与 AKAP 限制了相互作用。然而,推进在 CABYR 之间的证据和新关系,包括 AKAP,另外的 FS 蛋白质将在理解 FS 的基本生理学是有用的。在这研究,为不可溶解的蛋白质的 co-immunoprecipitation 的新策略,以及在有集体 spectrometry 和西方的污点的联合的标准 co-immunoprecipitation 方法,被采用探索在 CABYR, AKAP3 和 Ropporin 之间的关系。结果证明 AKAP3 是有由 anti-CABYR-A polyclonal 抗体的 CABYR 的 co-immunoprecipitated,并且,相反地, CABYR 也是有由 anti-AKAP3 polyclonal 抗体的 AKAP3 的 co-immunoprecipitated。包含蛋白质的另一象 RII 一样域, Ropporin,也是有 CABYR 的 co-immunoprecipitated,显示 Ropporin 是 CABYR 的绑定之一合伙。在 CABYR, AKAP3 和 Ropporin 之间的相互作用被酵母证实二混血儿的试金。进一步的分析显示出那 CABYR 不仅由它的 RII 领域绑在 AKAP3 而且除象 RII 一样领域以外通过另外的区域绑在 Ropporin。这是 CABYR 变体形成的第一示范不仅有 scaffolding 蛋白质 AKAP3 而且与在人的精子 FS 的另一象 RII 一样包含域的蛋白质的建筑群。 | Yan-Feng Li Wei He Arabinda Mandal Young-Hwan Kim Laura Digilio Ken Klotz Charles J Flickinger John C Herr | 2011 | Asian Journal of Andrology2011，13，2： | 5 |
| 2 | 电解磷化膜层的统计试验研究显示文摘与传统磷化相比,电解磷化工艺采用电能,具有速度更快,膜层更牢固、覆盖更完整,质量控制更方便等优点.对比了传统工艺与该电解磷化工艺的原理,说明了该工艺无铁淤泥生成的原因.通过统计试验讨论了化学成分对磷化膜质量、表面形貌、组分的影响及膜层质量对其暗度的影响.结果表明,膜层质量与溶液中的锌含量有直接关系,但膜层结构基本不受化学成分的影响,而膜层微观形貌与暗度与其质量有关.由此说明,通过控制磷化液中的锌含量可控制膜层质量,而通过检测膜层外观也可有效监控膜层质量. | Gabreil Kirsch William C Russell Ken Hacias 刘湘慧 | 2005 | 电镀与涂饰2005，24，11： | 3 |
| 3 | 当前围手术期处理模式:北欧五国结直肠外科医生调查显示文摘 | Kristoffer Lassen Pascal Hannemann Olle Ljungqvist Ken Fearon Cornelis H C Dejong Maarten F von Meyenfeldt Jonatan Hausel Jonas Nygren Jens Andersen Arthur Revhaug 王东 | 2005 | 英国医学杂志中文版2005，8，6： | 3 |
| 4 | Association of insulin resistance with serum ferritin and aminotransferases-iron hypothesis显示文摘AIM: To investigate the relationship of iron indices with diabetes mellitus(DM) in those without hemochromatosis.METHODS: This cross-sectional study examined data collected during the Third National Health and Nutrition Examination Survey(NHANES III). Only those who fasted properly and were not anemic with transferrin saturation < 45% were included(n = 6849). Insulin sensitivity and beta cell function were calculated from fasting glucose and insulin concentrations. Indices of iron metabolism were examined in the presence or absence of DM. We examined the relationship of insulin sensitivity and beta cell function with serum ferritin concentration. The influence of C-reactive protein and liver enzymes was also investigated.RESULTS: Serum ferritin concentration was significantly higher in diabetic subjects(P = 0.0001 to< 0.000001). The difference remained significant after adjustment for age, body mass index, alcohol consumption, and mineral/iron supplement(P = 0.03 to< 0.000001). In those who did not take insulin, serum ferritin concentration was negatively associated with insulin sensitivity(P = 0.05 to 0.00001), but not with beta cell function. The alanine aminotransferase was correlated with serum ferritin concentration(P = 0.02 to< 0.000001) but not with insulin sensitivity, suggesting the role of the liver in iron-associated insulin resistance.CONCLUSION: As most of diabetes is type 2 diabetes and insulin resistance is a cardinal feature of type 2diabetes, disordered iron metabolism could play a role in the pathogenesis of insulin resistance and type 2diabetes through its effect on liver function. | Jean Huang Rudruidee Karnchanasorn Horng-Yih Ou Wei Feng Lee-Ming Chuang Ken C Chiu Raynald Samoa | 2015 | World Journal of Experimental Medicine2015，5，4： | 2 |
| 5 | Differential geometrical conditions between geodesic curves and ruled surfaces显示文摘 | Ayyildiz N A Cken C Yucesan A | 2002 | Balkan Journal of Geometry and Its Applications2002，7，1： | 1 |
| 6 | Desorption kinetic of PCP-contaminated soil:effect of temperature显示文摘 | Ken K C Tse Shang-Lien Lo | 2002 | Water Research2002，36，： | 1 |
| 7 | Prevalence and risk factors of prostate cancer in Chinese men with PSA 4-10 ng/mL who underwent TRUS-guided prostate biopsy: the utilization of PAMD score 显示文摘 | FANG D KEN D ZHAO C | 2015 | Biomed Res Int2015，2015，59： | 1 |
| 8 | A review of polymer electrolyte membrane fuel cells:technology,applications,and needs on fundamental research显示文摘 | YUN W KEN C JEFFREY M | 2011 | Applied Energy2011，88，4： | 1 |
| 9 | Characterizationof the Fe/Mn-superoxide dismutase from diatom ( Thallas- siosira weissflogii) : cloning, expression, and property 显示文摘 | Ken C F Hsiung T M Huang Z X | 2005 | Agricultural and Food Chemistry2005，9，： | 1 |
| 10 | Optimization of a 3' -minor groove binder-DNA probe targeting the uidA gene for rapid identification of Escherichia coli O157:H7 using real-time PCR 显示文摘 | Ken J Yoshitomi Karen C Jinneman Stephen D Weagant | 2003 | Molecular and Cellular Probes2003，，17： | 1 |
| 11 | Multiplex real-time PCR method to identify shiga toxin genes stx1 and stx2 and escherichia coli O157: H7/Hserotype显示文摘 | KAREN C J KEN J Y STEPHEN D W | 2003 | Applied and Environmental Microbiology2003，69，10： | 1 |
| 12 | SmaB-world overlay P2P networks: construction, management and handling of dynamic flash crowds显示文摘 | Hui Ken Y K Lui John C S Yan David K Y | 2006 | Computer Networks2006，50，15： | 1 |
| 13 | Characteirzation of the Fe/Mn-superoxide dismutase from diatom (Thallassiosira weissflogii): Cloning, expression, and property显示文摘 | KEN C F HSIUNG T M HUANG Z X | 2005 | Agricultural and Food Chemistry2005，53，5： | 1 |
| 14 | Tribological properties of nanostructured and conventional WC-Co coatings deposited by plasma spraying显示文摘 | Zhu Y C Ken Y K Ding C X | 2001 | Thin Solid Films2001，388，12： | 1 |
| 15 | Area-Efficient VLSI Implementation for Paralld linear-Phase FIR Digital Filters of Odd Length Based on Fast Fill Algorit}ml显示文摘 | Yu-Chi T Ken C | 2012 | Transactions on Circuits System2012，59，6： | 1 |
| 16 | The role of natural resource amenities in attracting retirees: Implications for economic growth policy显示文摘 | Neelam C Poudyal Donald G Hodges H Ken Cordell | 2008 | Ecological Economics2008，2008，： | 1 |
| 17 | Cytokine and C-reactive protein profiles induced by porcine circovirus type 2 experimental infection in 3- week-old piglets显示文摘 | Leanne S S Ken M C Isabelle V | 2006 | Viral humunology2006，19，2： | 1 |
| 18 | 显示文摘 | Scott R S Ken B A Kathleen A C | 2002 | Applied Catalysis2002，231，： | 1 |
| 19 | Non-coding RNAs: regulators of disease 显示文摘 | Ryan J Taft Ken C Pang Timothy R Mercer | 2010 | J Pathology2010，220，2： | 1 |
| 20 | Can we improve the salinity tolerance of genotypes of Tuxodium by using varietal and hybrid crosses?显示文摘 | LI J Z DAVID L C KEN W K | 2010 | HortSeienee2010，45，12： | 1 |
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