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24篇 您的检索式:作者名="Kenakin"
    题名 作者 年代 出处 被引量
1Recent progress in discovery of small-molecule CCR5 ehemokine receptor ligands as HIV-1 inhibitors显示文摘Kazmierski W Bfulco N Kenakin T 2003Bioorg Med Chem2003,11,13:1
2Seven transmembrane receptors as shapeshifting proteins:the impact of allosteric modulation and functional selectivity on new drug discovery显示文摘Kenakin T Miller LJ 2010Pharmacol Rev2010,62,2:1
3Determining the potency and molecular mechanism of action of insurmountable antagonists 显示文摘Kenakin T Jenkinson S Watson C 2006J Pharmaeol Exp Ther2006,319,2:1
4G protein-coupled receptor allosterism and eomplexing显示文摘Christopoulos A Kenakin T 2002Pharmacol Rev2002,54,2:1
5Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery 显示文摘KENAKIN T MILLER LJ 2010Pharmacol Rev2010,62,2:1
6Collateral efficacy in drug discovery: taking advan- tage of the good (anosteric) nature of 7TM receptors显示文摘KENAKIN T 2007Trends Pharmacol Sci2007,28,8:1
7Efficacy as a vector: the relative prevalence and paucity of inverse agonism显示文摘Kenakin T 2004Mol Pharmacol2004,65,1:1
8Biased signalling and allosteric machines : new vistas and challenges for drug discovery 显示文摘Kenakin TP 2012Br J Pharmacol2012,165,6:1
9Seven transmembrane receptors as shapeshihing proteins: the impact of allosteric modulation and functional selectivity on new drug discovery显示文摘Kenakin T and Miller L J 2010Pharma col Rev2010,62,2:1
10Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and func- tional selectivity on new drug discovery显示文摘KENAKIN T MILLER L J 2010Pharmacol Rev2010,62,:1
11Functional, selectivity and biased receptor signaling显示文摘Kenakin T 2011J Pharmacol Exp Ther2011,336,2:1
12G-protein coupled receptors as allosteric machines显示文摘Kenakin T 2004Receptors Channels2004,10,2:1
13The CCR5 receptor- based mechanism of action of 873140, a potent allos- teric noncompetitive HIV entry inhibitor显示文摘Watson C Jenkinson S Kazmierski W Kenakin T 2005Mol Pharmacol2005,67,:1
14Predicting therapeutic value in the lead optimization phase of drug discovery 显示文摘Kenakin T 2003Nat Rev Drug Discov2003,2,6:1
15G protein-coupled receptor allosterism and complexing显示文摘Christopoulos A Kenakin T 2002Phannacol Rev2002,54,2:1
16Efficacy as a vector:The relative prevalence and paucity of inverse agonism显示文摘KENAKIN T 2004Mol Pharmacol2004,65,1:1
17The classification of seven transmembrance receptors in recombinant expression systems 显示文摘Kenakin T 1996Pharmacol Rev1996,48,3:1
18The classification of seven transmembrane receptors in recombinant expression systems显示文摘 1996Pharmacol Rev1996,48,3:1
19Predicting therapeutic value in the lead optimization phase of drug discovery显示文摘Kenakin T 2003Rev Drug Discov2003,2,6:1
20Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40:identification of agonist and antagonist small molecules显示文摘Briscoe CP Peat AJ McKeown SC Corbett DF Goetz AS Littleton TR McCoy DC Kenakin TP Andrews JL Ammala C Fornwald JA Ignar DM Jenkinson S 0,,05:1
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