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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | Infrared spectrum of SOF2显示文摘 | KENNETH O'LOANE J WILSON K M | 1955 | The Jourual of Chemical Physics1955，23，7： | 1 |
| 3 | Coq3orate Soccial Responsibility in Supply Chains of Global Brands:A Boundadaess Responsibility? Clarifications,Exceptions and hnplications显示文摘 | KENNETH M A ONYEKA K O PAUI N | 2008 | Journal of Business Ethics2008，81，1： | 1 |
| 4 | Efficient surface reconstruction from contours based ontwo-dimensional Delaunay triangulation 显示文摘 | WANG De-sheng OUBAY H O KENNETH M K | 2006 | International Journal for Numerical Methods in Engineering2006，65，5： | 1 |
| 5 | Biology and thera- peutic potential of hydrogen sulfide and hydrogen sul- fide - releasing chimeras 显示文摘 | KHOSROW K KENNETH R O | 2013 | Biochemical Pharmacol- ogy2013，85，5： | 1 |
| 6 | Symmetric varactor in 130 nm CMOS for frequency multiplier applications显示文摘 | Shim D Kenneth K O | | 0，，04： | 1 |
| 7 | NOSH-aspirin( NBS- 1120 ), a novel nitric oxide-and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth < i > in vitro and in a xenograft mouse model显示文摘 | MITALI C RAVINDER K KENNETH R O | 2012 | Biochemical and Bio- physical Research Communications2012，419，3： | 1 |
| 8 | Natural radioactivity in cultivated land in the vicinity of a phosphate fertilizer plant in Nigeria 显示文摘 | Mark C O Kenneth K A Felicitas U I | 2012 | Radiation Physics and Chemistry2012，，81： | 1 |
| 9 | Affordable terahertz electronics 显示文摘 | KENNETH K O | 2009 | IEEE Microwave Magazine2009，10，3： | 1 |
| 10 | Natural radio- activity in cultivated land in the vicinity of a phosphate fertilizer plant in Nigeria 显示文摘 | Mark C O Kenneth K A Felieitas U I | 2012 | Radiation Physics and Chemistry2012，，81： | 1 |
| 11 | The impact of adjuvant radiation therapy on survival in women with uterine carcinosarcoma显示文摘 | Clayton Smith D Kenneth Macdonald O Gaffney D K | 2008 | Radiother Oncol2008，88，2： | 1 |
| 12 | A 21--GHz 8-modulus prescaler and a 20--GHz phase-locked loop fabricated in 130--nm CMOS 显示文摘 | Yanping Ding Kenneth K O | 2007 | IEEE J So[ Sta Circ2007，42，6： | 1 |
| 13 | On-chip antennas in silicon ICs and their application 显示文摘 | KENNETH K O | 2005 | IEEE Transactions on Electron Devices JULY2005，52，7： | 1 |
| 14 | A 140-GHz fundamentalmode voltage-controlled oscillator in 90-nm CMOS tech-nology 显示文摘 | Cao Changhua Kenneth K O | 2006 | IEEE Microwave and Wireless Compo- nentsLetters2006，16，10： | 1 |
| 15 | Determination of poly-β- hydroxybutyrate and polyβ-hydroxyvalerate in activated sludge by gasliquid chromatography显示文摘 | Comeau Y Kenneth J H William K O | 1988 | Applied and Environmental Microbiology1988，54，9： | 1 |
| 16 | Print versus e- lectronic surveys: a comparison of two data collection methodologies 显示文摘 | Kenneth K B John R O Roger J C | 2002 | Journal of Operations Management2002，20，4： | 1 |
| 17 | Determination of poly-β- hydroxybutyrate and poly-β-hydroxyvalerate in activated sludge by gas-liquid chromatography 显示文摘 | Comeau Y Kenneth J H William K O | 1988 | Appl Env Micro1988，54，23： | 1 |
| 18 | A low-phase-noise and low-power multiband CMOS voltage-controlled oscillator显示文摘 | LI Z B KENNETH K O | 2005 | IEEE Journal of Solid-State Circuits2005，40，66： | 1 |
| 19 | Stanley:Interactive e- volution of particle systems for computer graphics and anima- tion显示文摘 | Hasting J E Guha R K Kenneth O | 2009 | IEEE Transaction on Evolutionary Computation2009，13，2： | 1 |
| 20 | On-chip Antennas in Silicon ICs and Their Application显示文摘 | KENNETH K O | 2005 | IEEE Transactions on Electron Devices2005，52，7： | 1 |
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