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| 1 | 人参减少 γ射线照射的淋巴细胞微核量(英文)显示文摘目的 评价中国人参对减少辐射诱导的人周围血 G0 期淋巴细胞 (PBL)微核量的作用。方法 采用细胞因子阻滞的微核法检测健康志愿者的血标本。体外 1 37Cs照射之前 ,每份血标本的单个核细胞培养以不同浓度 (0~ 2 0 0 0μg· m l- 1 )的人参根水提取物孵育 2 4 h。结果 (1)在 0 Gy时 ,每 10 0 0个双核 (BN )细胞的微核量是 11.3± 2 .7,人参水提取物≥ 5 0 0μg· ml- 1 时微核量下降 ,但微核量和人参水提取物的浓度之间的差异是显著的。 (2 )单独射线照射显著增加微核量 ,当暴露于 1Gy的照射时 ,随着培养介质中人参水提取物浓度的增加 ,微核量呈显著的线性降低 (R2 =0 .0 5 ,P =0 .0 0 2 ) ;对暴露于 1Gy辐射诱导的微核量 ,人参水提取物浓度在 15 0 0μg· m l- 1 时减少 4 6 .6 % ,浓度在 2 0 0 0μg·m l- 1时减少 5 7.6 % ;对暴露于 2 Gy辐射诱导的微核量的减少呈更强的线性相关 (R2 =0 .7,P=0 .0 0 0 1) ;(3)微核数据分析的结果呈现出与 Poisson模型相关的过度离散趋势。结果表明 :(1)人参水提取物浓度达 2 0 0 0 μg· ml- 1时 ,对 PBL 细胞毒作用无明显影响 ;(2 )人参水提取物浓度在 5 0 0 μg· ml- 1和 2 0 0 0 μg· ml- 1之间时 ,对抗 1 37Cs照射诱导的 MN发挥保护作用。 | 李同光 Ron R Allison Kevin F O'Brien Prabhaker G Khazanie Larry J Dobbs Jr. Peter J Kragel | 2004 | 新乡医学院学报2004，21，3： | 3 |
| 2 | Pedicle Morphology In Thoracic Adolescent Idiopathic Scoliosis: Is Pedicle Fixation an Anatomically Viable Technique?显示文摘 | Michael F O’Brien Lawrence G Lenke Steven Mardjetko Thomas G Lowe Yinong Kong Kevin Eck David Smith | 2000 | Spine2000，，18： | 2 |
| 3 | Selective killing of vaccinia virus by LL-37: Implications for eczema vaccinatum显示文摘 | Howell M D James F Kevin O | 2004 | Immunol2004，172，3： | 1 |
| 4 | The fate of nitro- gen applied to a mature Kentucky bluegrass turf显示文摘 | Kevin W F Kevin M O Crum J R | 2006 | Crop Science2006，46，： | 1 |
| 5 | The fate of nitrogen applied to a mature Kentucky bluegrass turf显示文摘 | Kevin W F Kevin M O Crum J R | 2006 | Crop Sci2006，46，： | 1 |
| 6 | Persistance of micronuclei in lymphocytes of cancer patients after radiotherapy显示文摘 | Lee Tung Kwang Allision Ron R O' Brien Kevin F | 2002 | RadiatRes2002，157，6： | 1 |
| 7 | Comparisons of electromagnetic and piezoelectric floating-mass transducers in human cadaveric temporal banes显示文摘 | KEVIN N O'CONNORD E F SUNIL P | 2011 | Hearing Research2011，272，12： | 1 |
| 8 | Partial nephrectomy: alternative treatment for selectes patients with renal cell carcinoma显示文摘 | Jose L F D Kevin R L Michael P O | 1998 | Urology1998，52，： | 1 |
| 9 | Low temperature oxidation of viscous crude oils显示文摘 | MOHAMMED R F KEVIN O M | 1990 | SPE Reservoir Engineering1990，5，4： | 1 |
| 10 | The fate of nitrogen applied to a mature Kentucky bluegrass turf 显示文摘 | Kevin W F Kevin M O Crum J R | 2006 | Crop Science2006，46，1： | 1 |
| 11 | Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial显示文摘 | Gerald S Falchook Georgina V Long Razelle Kurzrock Kevin B Kim Tobias H Arkenau Michael P Brown Omid Hamid Jeffrey R Infante Michael Millward Anna C Pavlick Steven J O’Day Samuel C Blackman C Martin Curtis Peter Lebowitz Bo Ma Daniele Ouellet Richard F Ke | 2012 | The Lancet . 2012 (9829)2012，，9829： | 1 |
| 12 | Strontium calcium ratios in Atlantic salmon (Salmosalar L) otoliths and observations on growth and maturation 显示文摘 | Kevin O F David G R Nobumichi S | 1998 | Canadian Journal of Fish Aquatic Science1998，55，： | 1 |
| 13 | Quantitative imaging biomarkers: A review of statistical methods for technical performance assessment显示文摘 | Raunig David L McShane Lisa M Pennello Gene Gatsonis Constantine Carson Paul L Voyvodic James T Wahl Richard L Kurland Brenda F Schwarz Adam J G?nen Mithat Zahlmann Gudrun Kondratovich Marina V O’Donnell Kevin Petrick Nicholas Cole Patricia | 2015 | Statistical Methods in Medical Research2015，，： | 1 |
| 14 | Low temperature oxidation of vis- cous crude oils 显示文摘 | Mohammed R F Kevin O M | 1990 | SPE Reservoir Engineering1990，5，4： | 1 |
| 15 | Low temperature oxidation of viscous crude oils显示文摘 | MOHAMMED R F KEVIN O M | 1990 | SPE Reservoir Engineering1990，5，4： | 1 |
| 16 | Tilapia Production Systems in the Americas: TechnoIogical Ad- vances, Trends, and Challenges 显示文摘 | WATANAB W O THOMAS M L KEVIN F | 2002 | Reviews in Fisheries Science2002，10，34： | 1 |
| 17 | Trends and risk factors for opioid administration for non-emergent lower back pain显示文摘BACKGROUND Non-emergent low-back pain(LBP)is one of the most prevalent presenting complaints to the emergency department(ED)and has been shown to contribute to overcrowding in the ED as well as diverting attention away from more serious complaints.There has been an increasing focus in current literature regarding ED admission and opioid prescriptions for general complaints of pain,however,there is limited data concerning the trends over the last decade in ED admissions for non-emergent LBP as well as any subsequent opioid prescriptions by the ED for this complaint.AIM To determine trends in non-emergent ED visits for back pain;annual trends in opioid administration for patients presenting to the ED for back pain;and factors associated with receiving an opioid-based medication for non-emergent LBP in the ED METHODS Patients presenting to the ED for non-emergent LBP from 2010 to 2017 were retrospectively identified from the National Hospital Ambulatory Medical Care Survey database.The“year”variable was transformed to two-year intervals,and a weighted survey analysis was conducted utilizing the weighted variables to generate incidence estimates.Bivariate statistics were used to assess differences in count data,and logistic regression was performed to identify factors associated with patients being discharged from the ED with narcotics.Statistical significance was set to a P value of 0.05.RESULTS Out of a total of 41658475 total ED visits,3.8%(7726)met our inclusion and exclusion criteria.There was a decrease in the rates of non-emergent back pain to the ED from 4.05%of all cases during 2010 and 2011 to 3.56%during 2016 and 2017.The most common opioids prescribed over the period included hydrocodone-based medications(49.1%)and tramadol-based medications(16.9),with the combination of all other opioid types contributing to 35.7%of total opioids prescribed.Factors significantly associated with being prescribed narcotics included age over 43.84-years-old,higher income,private insurance,the obtainment of radiographic imaging in the ED,and region of the United States(all,P<0.05).Emergency departments located in the Midwest[odds ratio(OR):2.42,P<0.001],South(OR:2.35,<0.001),and West(OR:2.57,P<0.001)were more likely to prescribe opioid-based medications for non-emergent LBP compared to EDs in the Northeast.CONCLUSION From 2010 to 2017,there was a significant decrease in the number of nonemergent LBP ED visits,as well as a decrease in opioids prescribed at these visits.These findings may be attributed to the increased focus and regulatory guidelines on opioid prescription practices at both the federal and state levels.Since nonemergent LBP is still a highly common ED presentation,conclusions drawn from opioid prescription practices within this cohort is necessary for limiting unnecessary ED opioid prescriptions. | Chukwuweike U Gwam Ahmed K Emara Noor Chughtai Sameer Javed T David Luo Kevin Y Wang Morad Chughtai Tadhg O'Gara Johannes F Plate | 2021 | World Journal of Orthopedics2021，12，9： | 0 |
| 18 | 人参的放射保护作用(英文)显示文摘本文综述了近年各国文献中各种人参对哺乳动物细胞和人周围血淋巴细胞的放射保护作用。不同文献所采用LD50、克隆形成单位法、非同位素的原位DNA末端标记技术、磷酸盐活性和脂质过氧化水平、空斑形成单位法和细胞因子阻滞的微核法等体内外实验结果表明,不同人参制品有显著的放射保护作用,其水溶性提取物的保护作用优于单体成分。人参除抗肿瘤作用外,对放射治疗的肿瘤病人是一个有效的放射保护剂。 | 同光李 Ron R Allison Roberta M Johnke Charles J Kovacs Mickael J Cariveau Kevin F O’Brien Larry J Dobbs Jr | 2005 | 新乡医学院学报2005，22，1： | 0 |
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