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| 1 | Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life. | Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam | 2013 | World Journal of Gastroenterology2013，19，46： | 6 |
| 2 | Clinical epidemiology of ulcerative colitis in Arabs based on the Montréal classification显示文摘AIM:To determine the clinical,epidemiological and phenotypic characteristics of ulcerative colitis(UC)in Saudi Arabia by studying the largest cohort of Arab UC patients.METHODS:Data from UC patients attending gastroenterology clinics in four tertiary care centers in three cities between September 2009 and September 2013were entered into a validated web-based registry,inflammatory bowel disease information system(IBDIS).The IBDIS database covers numerous aspects of inflammatory bowel disease.Patient characteristics,disease phenotype and behavior,age at diagnosis,course of the disease,and extraintestinal manifestations were recorded.RESULTS:Among 394 UC patients,males comprised51.0%and females 49.0%.According to the Montréal classification of age,the major chunk of our patients belonged to the A2 category for age of diagnosis at17-40 years(68.4%),while 24.2%belonged to the A3category for age of diagnosis at>40 years.According to the same classification,a majority of patients had extensive UC(42.7%),35.3%had left-sided colitis and29.2%had only proctitis.Moreover,51.3%were in remission,16.6%had mild UC,23.4%had moderate UC and 8.6%had severe UC.Frequent relapse occurred in17.4%patients,infrequent relapse in 77%and 4.8%had chronic disease.A majority(85.2%)of patients was steroid responsive.With regard to extraintestinal manifestations,arthritis was present in 16.4%,osteopenia in 31.4%,osteoporosis in 17.1%and cutaneous involvement in 7.0%.CONCLUSION:The majority of UC cases were young people(17-40 years),with a male preponderance.While the disease course was found to be similar to that reported in Western countries,more similarities were found with Asian countries with regards to the extent of the disease and response to steroid therapy. | Othman R Alharbi Nahla A Azzam Ahmed S Almalki Majid A Almadi Khalid A Alswat Nazia Sadaf Abdulrahman M Aljebreen | 2014 | World Journal of Gastroenterology2014，20，46： | 2 |
| 3 | The impact of diagenesis on the heterogeneity of sandstone reservoirs: A review of the role of depositional facies and sequence stratigraphy显示文摘 | Morad S Khalid A R Ketzer J M | 2010 | AAPG Bulletin2010，94，8： | 1 |
| 4 | Effect of paclobutrazol on growth and yield of tornato显示文摘 | Hafeezur R M AsK K Khalid M K | 1989 | Pakistan J Agric Res1989，0，1： | 1 |
| 5 | 1-Gb/s trans m ission over a phosphorescent while LED by using rate-adaptive discrete multitone modulation显示文摘 | Khalid A M Cossu G Corsini R | 2012 | IEEE Photonics Journal2012，4，5： | 1 |
| 6 | Tuning of a neuro-fuzzy controller by genetic algorithm显示文摘 | SENG T L KHALID M B YUSOF R | 1999 | IEEE Trans Syst Man Cybern1999，29，2： | 1 |
| 7 | Kernel methods and support vector machines for handwriting recognition显示文摘 | Ahmad A Khalid M Yusof R | 2002 | IEEE Student Conference on Research and Development Proceedings2002，13，2： | 1 |
| 8 | Systematic review:comparing routine and selective invasive strat- egies for the acute coronary syndrome显示文摘 | Qayyum R Khalid M R Adomaityte J | 2008 | Ann Intern Med2008，148，3： | 1 |
| 9 | Dynamic biosorption of Zn(II) and Cu (II) using pretreated Rosa gruss an teplitz (red rose ) distillation sludge 显示文摘 | Bhatti H N Khalid R Hanif M A | 2009 | Chemical Engineering Journal2009，148，23： | 1 |
| 10 | Optimization of fuzzy model using genetic algorithm for process control applica tion显示文摘 | Yusof R Rahman R Z A Khalid M | 2011 | Journal of the Franklin Institute2011，348，7： | 1 |
| 11 | Dynamic biosorption ofZn( Ⅱ ) and Cu(Ⅱ) using pretreated Rosa gross an teplitz (red rose) distillation sludge显示文摘 | Bhatti H N Khalid R Hanif M A | 2009 | Chemical Engineering Journal2009，148，23： | 1 |
| 12 | An efficient mutual authentication and access control scheme for wireless sensor networks in healthcare显示文摘 | LE Xuan-hung KHALID M SANKAR R | 2011 | Journal of Networks2011，6，3： | 1 |
| 13 | Optimization of fuzzy model using genetic algorithm for process control application显示文摘 | Yusof R Rahman R Z A Khalid M | 2011 | J of the Franklin Institute2011，348，7： | 1 |
| 14 | MIMO furnace control with neu-ral networks 显示文摘 | Khalid M Omatu S Yusof R | 1993 | IEEE Transactions on Control SystemsTechnology1993，1，4： | 1 |
| 15 | Adaptive neuro-fuzzy control system by RBF and GRNN neural networks 显示文摘 | SENG T L KHALID M YUSOF R | 1998 | Intelligent and Robotic Systems1998，，23： | 1 |
| 16 | The role of binder content on microstmcture and properties of a Cu-base active brazing filler metal for diamond and cBN显示文摘 | ELSENER H R KLOTZ U E KHALID F A PIAZZA D KISER M | 2005 | Advanced Engineering Materials2005，7，5： | 1 |
| 17 | Application of kernel-genetic algorithm as nonlinear feature selection in tropical wood species recognition system显示文摘 | Yusof R Khalid M Khairuddin A S M | 2013 | Computers and Electronics in Agriculture2013，93，4： | 1 |
| 18 | Tuning of a neuro-fuzzy controller by genetic algorithm显示文摘 | SENG T L KHALID M B YUSOF R | 1999 | IEEE Transactions on Systems Man and Cybernetics Part B1999，29，2： | 1 |
| 19 | Synthesis and properties of waterborne self-crosslinkable sulfo-urethane silanol dispersions 显示文摘 | Kevin Lewandowski Larry R Krepski Daniel E Mickus Ralph R Roberts Steven M Heilmann Wayne K Larson Mark D Purgett Steven D Koecher Stephen A Johnson Daniel J Mcgurran Chris J Rueb Sadanand V Pathre Khalid A M Thakur | 2002 | Journal of Polymer Science Part A : Polymer Chemistry2002，40，17： | 1 |
| 20 | Self-tuning PID control: A multivariable derivation and application显示文摘 | YUSOF R OMATU S KHALID M B | 1994 | Automatica1994，30，12： | 1 |
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