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| 1 | TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization显示文摘皮肤的神经原的发炎(CNI ) 是被导致的发炎(或提高) 在由从感觉神经末端的 neuropeptides 的版本的皮肤。临床的表明主要是象瘙痒和红斑那样的感觉、脉管的混乱。短暂受体潜力 vanilloid 1 并且 ankyrin 1 (TRPV1 和 TRPA1,分别地) 是知道明确地参予疼痛和 CNI 的非选择的阳离子隧道。TRPV1 和 TRPA1 在感觉神经的一个大子集被共同表示,在他们集成众多的有害刺激的地方。两条隧道的表示也在皮肤在感觉神经以外远延长,现在是清楚的,在 keratinocytes,桅杆房间,树枝状的房间,和 endothelial 房间也发生。在这些 non-neuronal 房间, TRPV1 和 TRPA1 也充当 nociceptive 传感器并且加强煽动性的过程。这评论在在感觉神经原和 non-neuronal 皮肤房间导致或维持 CNI 的煽动性的基因的调整讨论 TRPV1 和 TRPA1 的角色。另外,这评论由支持 CNI 的自我维护的另外的内长的煽动性的调停人提供关于两条 TRP 隧道的细胞内部的促进感受性小径的当前的研究的一篇摘要。 | Olivier Gouin Killian L'Herondelle Nicolas Lebonvallet Christelle Le Gall-lanotto Mehdi Sakka Virginie Buhe Emmanuelle PIee-Gautier Jean-Luc Carre Luc Lefeuvre Laurent Misery~,Raphaele Le Garrec | 2017 | Protein & Cell2017，8，9： | 45 |
| 2 | 珠江三角洲世界工厂的非正规职业中介及其作用——以广东省东莞市塘厦镇为例显示文摘国内外现有研究认为,农民工的求职渠道非常单一,主要依赖社会关系网络。本文选取典型的珠江三角洲世界工厂所在地——广东省东莞市塘厦镇为案例,对非正规职业中介机构进行了深入调查研究。发现非正规中介机构在农民工的求职过程中发挥着重要作用,帮助农民工实现灵活、即时的就业,其存在是在我国转型期市场改革不断深入的背景下,企业/工厂的用工需求、农民工的求职需要、中介机构的逐利目的和地方政府的宽容态度共同作用的结果。非正规职业中介机构是市场动力作用下的新型农民工非正规求职渠道,是原有的社会关系网络求职渠道的延伸。研究表明,在现阶段中国城市化过程中,非正规的动力在解决农民工求职乃至城市化过程中具有重要的作用。 | 薛德升 林婷 KRAAS Frauke KILLIAN Pamela | 2010 | 地理研究2010，29，10： | 11 |
| 3 | New Pd(Ⅱ)- and Ni(Ⅱ)-Based Catalysts for Polymerization of Ethylene and α-Olefins显示文摘 | Johnson L K Killian C M Brookhart M | | 0，，： | 6 |
| 4 | Copolymerization of Ethylene and Propyiene with Functionalized Vinyl Monomers by PalladiumII) Catalysts显示文摘 | Johnson L K Killian C M Arthur S D | | 0，，： | 4 |
| 5 | Bose-Einstein condensation of atomic hydrogen显示文摘 | FRIED G D KILLIAN T C WILLMANN L | 1998 | Phys Rev Lett1998，81，18： | 2 |
| 6 | 在男吸烟者之中的白血球 DNA methylation 和 colorectal 癌症显示文摘 AIM: To explore the association between methylation in leukocyte DNA and colorectal cancer (CRC) risk in male smokers using the α-tocopherol, β-carotene cancer prevention study. METHODS: About 221 incident CRC cases, and 219controls, frequency-matched on age and smoking intensity were included. DNA methylation of 1505 CpG sites selected from 807 genes were evaluated using Il-lumina GoldenGate Methylation Cancer Panel I in prediagnostic blood leukocytes of study subjects. Tertiles of methylation level classified according to the distribution in controls for each CpG site were used to analyze the association between methylation level and CRC risk with logistic regression. The time between blood draw to cancer diagnosis (classifying cases according to latency) was incorporated in further analyses using proportional odds regression. RESULTS: We found that methylation changes of 31 CpG sites were associated with CRC risk at P<0.01 level. Though none of these 31 sites remained statistically significant after Bonferroni correction, the most statistically significant CpG site associated with CRC risk achieved a Pvalue of 1.0×10-4 . The CpG site is located in DSP gene, and the risk estimate was 1.52 (95% CI: 0.91-2.53) and 2.62 (95% CI: 1.65-4.17) for the second and third tertile comparing with the lowest tertile respectively. Taking the latency information into account strengthened some associations, suggesting that the methylation levels of corresponding sites might change over time with tumor progression. CONCLUSION: The results suggest that the methylation level of some genes were associated with cancer susceptibility and some were related to tumor development over time. Further studies are warranted to confirm and refine our results. | Keith Killian Stephanie Weinstein Jarmo Virtamo Margaret Tucker Philip Taylor Demetrius Albanes Paul Meltzer Neil Caporaso | 2012 | World Journal of Gastrointestinal Oncology2012，4，8： | 2 |
| 7 | Secure spread spectrum watermarking for multimedia显示文摘 | COX I J KILLIAN J LEIGHTON T | | 0，，12： | 2 |
| 8 | Secure spread spectrum watermarking for multimedia 显示文摘 | Cox I J Killian J Leighton F T | 1997 | IEEE Trans Image Processing1997，6，12： | 1 |
| 9 | Serum proteomics in cancer diagnosis and management显示文摘 | Rosenblatt KP Bryant Greenwood P Killian JK | 2004 | Annu Rev Med2004，55，97： | 1 |
| 10 | Secure spread spectrumwater marking for multimedia显示文摘 | Cox I J Killian J Leighton F T | 1997 | IEEE Trans Image Processing1997，6，： | 1 |
| 11 | Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate 显示文摘 | Liu F Killian JK Yang M | 2010 | Oncogene2010，29，25： | 1 |
| 12 | Potent morphiceptin analogs : structure activity relationships and morphine - like activities 显示文摘 | CHANG K J WEI E T KILLIAN A | 1983 | J Pharmaol Exp Ther1983，227，2： | 1 |
| 13 | Carbamazepine in the treatment of neuralgia显示文摘 | Fromm GH | 1968 | Arch Neurol1968，19，： | 1 |
| 14 | Preparation of linear α-olefin using cationic nickel(Ⅱ) α-di-imine catalysts显示文摘 | Johnson L K Brookhart M | 1997 | Organometallics1997，，16： | 1 |
| 15 | 5α-reductase isoenzymes 1 and 2 in the rat testis during postnatal development显示文摘 | Killian J Pratis K Clifton R J | 2003 | Biol Reproduction2003，68，： | 1 |
| 16 | Reported Gains in Student I_carning o Academic Disciplines Make a Difference? 显示文摘 | PIKE G R KILLIAN T S | 2001 | Research in Higher Education2001，42，： | 1 |
| 17 | Generation of recombinant antibody fragments that canine dendritic cells by phage display technology显示文摘 | Fitting J Killian D Junghanss C | | 0，，03： | 1 |
| 18 | New Pd( 11 ) - and Ni( 11 ) -Based Catalysts for Polymerization of Ethylene and a - Olefins显示文摘 | Johnson L K Killian C M Brookhart M | | 0，，： | 1 |
| 19 | Predictive va- lidity of the functional movement screene in a population of recreational runners training for a half marathon 显示文摘 | Hoover D Killian CB Bourcier B | 2008 | Medicine & Science in Sports & Exercise2008，40，5： | 1 |
| 20 | Experimental autoirnmunemotonemon disease显示文摘 | Appel SH Killian JM | 1989 | Ann Neurol1989，26，： | 1 |
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