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1714篇 您的检索式：作者名="Kim YM"

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	题名	作者	年代	出处	被引量
1	Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities显示文摘Aim:To clarify the mechanism of the therapeutic action of icariin on erectlile dysfunction(ED).Methods:PDE5 was isolated from the human platelet and PDE4 form the rat liver tissue using the FPLC system (Pharmacia,Milton Keynes,UK)and the Mono Q column.The inhibitory effects of icariin on PDE5 and PDE4 activities were investigated by the two-step radioisotope procedure with [^3H]-c GMP/[^3H]-cAMP.Papaverine served as the control drug.Results:Icariin and papaverine showed dose-dependent inhibitory effects on PDE5 and PDE4 activities.The IC50 of Icariin and papaverine on PDE5 were 0.432μ mol/L and 0.680μmol/L,respectively and those on PDE4,73.50μmol/L and 3.07μmol/L,respectively.The potencies of selectivity of icariin and papaverine on PDE5(PDE4/PDE5 of IC50)were 167.67 times and 4.54 times,respectively.Conclusion:Icariin is a cGMP-specific PDE5 inhibitor that may be developed into an oral effective agent for the treatment of ED.	ZC Xin EK Kim CS Lin WJ Liu L Tian YM Yuan J Fu	2003	Asian Journal of Andrology2003，5，1：	38
2	External vs endoscopic approach for inverted papilloma of the sino-nasal cavities:a retrospective study of 136 caaes显示文摘	Kim YM Kim HS Park JY	2008	Acta Otolaryngol2008，128，8：	1
3	Serum lipid and fatty acid profiles in adriamycin-treated rats after administration of L-carnitine显示文摘	Hong YM Kim HS Yoon HR	2002	Ped iatr Res2002，51，2：	1
4	Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia 显示文摘	Chaiworapongsa T Romero R Kim YM	2005	J Matem Fetal Neonatal Med2005，17，1：	1
5	Expression of MAGE-1 ,-2 ,and -3 genes in gastric carcinomas and cancer cell lines derived from Korean patients 显示文摘	Kim YM Lee YH Shin SH Kim EH Choi YW Lee KM	2001	J Korean Med Sci2001，16，1：	1
6	Endostatin inhibits erdothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase显示文摘	Kim YM Jang JW Lee OH Yeon J Choi EY Kim KW	2000	Cancer Res2000，60，19：	1
7	Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase显示文摘	Kim YM Jang Jw Lee OH	2000	Cancer Res2000，60，19：	1
8	Green tea extract inhibits paraquatinduced pulmonary fibrosis by suppression ofoxidative stress and endothelin-1 expression显示文摘	Kim HR Park BK Oh Ym	2006	Am J Lung2006，184，5：	1
9	Assessment of risk factors for Korean children with Kawasaki dis- ease显示文摘	Kim JJ Hong YM Yun SW Han MK Lee KY Song MS	2012	Pediatr Cardiol2012，33，4：	1
10	Enhanced lycopene production in Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate显示文摘	Yoon SH Lee YM Kim JE		0，，06：	1
11	Green tea extract inhibits paraquat-induced pulmonary fibrosis by suppression of oxidative stress and endothelin-1 expression显示文摘	Kim HR Park BK Oh YM a al	2006	Lung2006，184，5：	1
12	Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-α reduced apoptosis by inducing heat shock protein 70 expression 显示文摘	9,Kim YM Watkins SC Billiar TR	1997	J Biol Chem1997，272，2：	1
13	Macrophages and apoptotic cell clearance during pregnancy显示文摘	ABRAHAMS VM KIM YM STRASZEWSKI SL	2004	Am J Reprod Immunol2004，51，4：	1
14	Factors that influence intraocular pressure after cataract surgery in primary glaucoma 显示文摘	Lee YH Yun YM Kim SH	2009	Can J Ophthalmol2009，44，6：	1
15	UNC93B1 delivers nucleotide-sensing Toll-like receptors to endolysosomes显示文摘	Kim YM Brinkmann MM Paquet ME	2008	Nature2008，452，7184：	1
16	Rosiglitazone attenu-ates hypoxia-induced pulmonary arterial hypertension inrat显示文摘	Kim EK Lee JH Oh YM	2010	Respirology2010，15，4：	1
17	A seroprevalence study of poliovirus antibody among primary schoolchildren in Korea 显示文摘	Jee YM Cheon DS Kim KS	2004	Epidemiol Infect2004，132，2：	1
18	A novel a-glucosidase in- hibitor from pine bark显示文摘	Kim YM Wang MH Rhee HI	2010	Carbohyd Res2010，339，3：	1
19	Comparison of the effectiveness of nonablative fractional laser versus ablative fractional laser in thyroidectomy scar prevention: A pilot study 显示文摘	Kim HS Lee JH Park YM	2012	J Cosmet Laser Ther2012，14，2：	1
20	Different cell cycle modulation by cele- coxib at different concentrations显示文摘	Kim YM Pyo H	2013	Cancer Biother Radio- pharm2013，28，2：	1

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