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| 1 | Bariatric surgery in patients with non-alcoholic fatty liver disease-from pathophysiology to clinical effects显示文摘Non-alcoholic fatty liver disease(NAFLD) is increasingly recognized as a significant liver disease,and it covers the disease spectrum from simple steatosis with a risk of development of non-alcoholic steatohepatitis(NASH) to fibrosis,subsequent cirrhosis,end-stage liver failure,and liver cancer with a potential need for liver transplantation.NAFLD and NASH are closely related to obesity,metabolic syndrome,and type 2 diabetes(T2 D).The role of gut hormones,especially glucagon-like peptide 1(GLP-1),is important in NAFLD.Bariatric surgery has the potential for inducing great weight loss and may improve the symptoms of metabolic syndrome and T2 D.Recent data demonstrated significant effects of bariatric surgery on GLP-1 and other gut hormones and important lipid metabolic and inflammatory abnormalities in the pathophysiology of NAFLD.Therefore,bariatric surgery may reverse the pathological liver changes in NAFLD and NASH patients.In the present review,we describe NAFLD and NASH pathophysiology and the primary effects of bariatric surgery on metabolic pathways.We performed a systematic review of the beneficial and harmful effects and focused on changes in liver disease severity in NAFLD and NASH patients.The specific focus was liver histopathology as assessed by the invasive liver biopsy.Additionally,we reviewed several non-invasive methods used for the assessment of liver disease severity following bariatric surgery. | Tea L Laursen Christoffer A Hagemann Chunshan Wei Konstantin Kazankov Karen L Thomsen Filip K Knop Henning Grønbæk | 2019 | World Journal of Hepatology2019，11，2： | 11 |
| 2 | Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes: differences and similarities显示文摘 | Lund A Knop FK Vilsboll T | 2014 | Eur J Intern Med2014，25，5： | 1 |
| 3 | The mechanism of zeolite Y destruction by steam in the presence of vanadium显示文摘 | Trujilo C A Uribe U N Knops G | 1997 | Journal ofCatalysis1997，168，1： | 1 |
| 4 | Treatment of steroid-resistant acute GVHD with OKT3 and high-dose steroids results in better disease control and lower incidence of infectious complications when compared to high-dose steroids alone:a randomized multicenter trial by the EBMT Chronic Leukemia Working Party显示文摘 | Knop S Hebart H Gratwohl A | 2007 | Leukemia2007，21，8： | 1 |
| 5 | Phenolic resin:Chemistry , Application and Performance , Future Direction显示文摘 | Knop A Pilate L A | 1985 | Springer-Verlag1985，，： | 1 |
| 6 | Mechanisms ofplant species impacts on ecosystem nitrogen cycling显示文摘 | Knops J M H Bradley K L Wedin D A | 2002 | Ecology Letters2002，5，3： | 1 |
| 7 | Reconstruction of liver tissue in vitro: geometry of characteristic flatbed,hollow fiber,and spouted bed bioreactors with reference to the in vivo liver显示文摘 | Bader A Knop E Fruhauf N | 1995 | Artif Organs1995，19，9： | 1 |
| 8 | Mechanisms of plant species impacts on ecosystem nitrogen cycling显示文摘 | Knops J M H Bradley K L Wedlin D A | 2002 | Ecol Let2002，，5： | 1 |
| 9 | Recruitment of an ar- ea involved in eye movements during mental arithmetic显示文摘 | Knops A Thirion B Hubbard EM | 2009 | Sci- ence2009，324，5934： | 1 |
| 10 | Increased N availability in grassland soils modifies their microbial communities and decreases the abundance of arbuscular mycorrhizal fungi显示文摘 | Bradley K Drijber R A Knops j | 2006 | Soil Biology and Biogeochemistry2006，38，： | 1 |
| 11 | Human basophils a unique biological instrument to detect the allergenicity of food 显示文摘 | SABATO V VAN HENGEL A J DE KNOP K J | 2011 | Investig Allergol Clin Immunol2011，21，3： | 1 |
| 12 | Mechanisms of plant species impacts on ecosystem nitrogen cycling显示文摘 | Knops J M H Bradley K L Wedlin D A | 2002 | Ecology Letters2002，5，： | 1 |
| 13 | Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes : differences and similar- ities显示文摘 | Lund A Knop FK Vilsboll T | 2014 | Eur J Intern Ned2014，25，5： | 1 |
| 14 | Normalized mutual information hased registeration using h - means clustering and shading correction 显示文摘 | Knops Z F Maintz J B A Viergever M A | 2006 | Medical Image Analysis2006，10，3： | 1 |
| 15 | Bispecific T-Cell engager (BITE) antibody construct blinatumomab for the treatment of patients with relapsed/refractory Non-Hodgkin lymphoma: final results from a phase I study显示文摘 | Goebeler ME Knop S Viardot A | 2016 | J Clin Oncol2016，3410，： | 1 |
| 16 | An Alternative to Quintessence显示文摘 | KNOP R A ALDERING G AMANULLAH R | 2003 | APJ2003，598，： | 1 |
| 17 | Increased Navail-ability in grassland soil smodifies their microbial com-munities and decreases the abundance of arbuscularmycorrhizal fungi显示文摘 | Bradley K Drijber R A Knops J | 2006 | Soil Biology Biochemistry2006，38，7： | 1 |
| 18 | Preparation of sustained release matrix pellets by melt agglomeration in the fluidized bed:influence of formulation variables and modelling of agglomerate growth显示文摘 | A Pauli-Bruns K Knop B C Lippold | | 0，，： | 1 |
| 19 | Normalized mutualinformation based registration using k-means clustering and shading correction显示文摘 | Knops Z F Maintz J B A Viergever M A | 2006 | Medical Image Analysis2006，10，3： | 1 |
| 20 | Impaired regulation of the incretineffect in patients with type 2 diabetes 显示文摘 | Bagger JI Knop FK Lund A | 2011 | J Clin Endocrinol Metab2011，96，3： | 1 |
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