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| 1 | Favorable lifestyle before diagnosis associated with lower risk of screen-detected advanced colorectal neoplasia显示文摘AIM: To investigate the association between adherence to health recommendations and detection of advanced colorectal neoplasia(ACN) in colorectal cancer(CRC) screening.METHODS: A total of 14832 women and men were invited to CRC screening, 6959 in the fecal immunochemical test arm and 7873 in the flexible sigmoidoscopy arm. These were also sent a self-reported lifestyle questionnaire to be completed prior to their first CRC screening. A lifestyle score was created to reflect current adherence to healthy behaviors in regard to smoking, body mass index, physical activity, alcohol consumption and food consumption, and ranged from zero(poorest) to six(best). Odds ratios(ORs) and 95%CIs were calculated using multivariable logistic regression to evaluate the association between the single lifestyle variables and the lifestyle score and the probability of detecting ACN.RESULTS: In all 6315 women and men completed the lifestyle questionnaire, 3323(53%) in the FIT arm and 2992(47%) in the FS arm. This was 89% of those who participated in screening. ACN was diagnosed in 311(5%) participants of which 25(8%) were diagnosed with CRC. For individuals with a lifestyle score of two, three, four, and five-six, the ORs(95%CI) for the probability of ACN detection were 0.82(0.45-1.16), 0.43(0.28-0.73), 0.41(0.23-0.64), and 0.41(0.22-0.73), respectively compared to individuals with a lifestyle score of zero-one. Of the single lifestyle factors, adherence to non-smoking and moderate alcohol intake were associated with a decreased probability of ACN detection compared to being a smoker or having a high alcohol intake 0.53(0.42-0.68) and 0.63(0.43-0.93) respectively.CONCLUSION: Adopted healthy behaviors were inversely associated with the probability of ACN detection. Lifestyle assessment might be useful for risk stratification in CRC screening. | Markus D Knudsen Thomas de Lange Edoardo Botteri Dung-Hong Nguyen Helge Evensen Chloé B Steen Geir Hoff Tomm Bernklev Anette Hjartaker Paula Berstad | 2016 | World Journal of Gastroenterology2016，22，27： | 3 |
| 2 | Biomarkers for occupational diesel exhaust exposure monitoring Biomodem-a study in underground mining显示文摘 | P T J Scheepers D Coggon L E Knudsen | 2002 | Toxicology Letters2002，134，： | 2 |
| 3 | Ultrasound- guided renal biopsy with biopsy gun techniqueefficacy and complications 显示文摘 | CHRISTENSEN J LINDEQUIST S KNUDSEN D U | 1995 | Acta Radiologica1995，36，3： | 1 |
| 4 | Winter-time convection in open-graded embankments显示文摘 | Goering D J Instanes A Knudsen S | 1996 | Cold Regions Science and Technology1996，24，1： | 1 |
| 5 | The busiest of all ribosomal assistants:elongation factor Tu显示文摘 | Kavaliauskas D Nissen P Knudsen C R | | 0，，13： | 1 |
| 6 | The use of stents in contemporary urology显示文摘 | Chew B H Knudsen B E Denstedt J D | 2004 | Curr Opin Urol2004，14，2： | 1 |
| 7 | Shift -share analysis:further examination of models for the description of economic change显示文摘 | KNUDSEN D C 2000 | 2000 | Socio -Economic Planning Sciences2000，34，3： | 1 |
| 8 | Biological seed treatment of cereals with fresh and long-term stored formulations of Clonostachys rosea: Biocontrolefficacy against Fusarium culmorum显示文摘 | Jensen B Knudsen I M B Jensen D F | 2000 | European Journal of Plant Pathology2000，106，： | 1 |
| 9 | A review of catalytic upgrading of bio-oil to engine fuels显示文摘 | MORTENSEN P M GRUNWALDT J D JENSEN P A KNUDSEN K G JENSEN A D | 2011 | Appl Catal A: Gen2011，407，1： | 1 |
| 10 | Oral cavity and esopha- geal carcinogenesis modeled in carcinogen-treated mice 显示文摘 | Tang XH Knudsen B Bemis D | 2004 | Clin Cancer Res2004，10，1： | 1 |
| 11 | Selection of resistant Streptococcus pneumoniae during penicillin treatment in vitro and in three animal models显示文摘 | Knudsen J D Odenholt I Erlendsdottir H et aI | 2003 | Antimicrobial Agents Chemotherapy2003，47，8： | 1 |
| 12 | Biomarkers for occupational diesel exhaust exposure monitoring (BIOMODEM): A study in underground mining显示文摘 | SCHEEPERS P T J COGGON D KNUDSEN L E | 2002 | Toxicology Letters2002，134，： | 1 |
| 13 | Regeneration of fertile barley plants from mechanically isolated protoplasts of the fertilized egg cell 显示文摘 | Holm P B Knudsen S Mouritzen P Negri D Olson F L Roue A C | 1994 | Plant Cell1994，6，： | 1 |
| 14 | Organic nitrogen compounds in gasoil blends, their hydrotreated products and the importance to hydrotreatment显示文摘 | ZEUTHEN P KNUDSEN K G WHITEHURST D D | 2001 | Catalysis Today2001，65，24： | 1 |
| 15 | The use of stents in contemporary urology显示文摘 | Chew B H Knudsen B E Denstedt J D | 2004 | Curr Opin Urol2004，14，2： | 1 |
| 16 | Postmenopausalendometriosis显示文摘 | Oxholm D knudsen UB Kryger-Baggesen N | 2007 | Acta Obstet Gynecol Stand2007，86，10： | 1 |
| 17 | Structural and dynamical properties of aqueous mixtures of pectin and chitosan显示文摘 | Hiorth Marianne Kjoniksen Anna-Lena Knudsen Kenneth D | 2005 | European Polymer Journal2005，41，： | 1 |
| 18 | The propagation of sound waves in drill strings显示文摘 | Drumheller D S Knudsen S D | 1995 | Journal of the Acoustical Society of America1995，97，4： | 1 |
| 19 | Shift-share Analysis:Further Examination of Models for the Description of Economic Change 显示文摘 | Knudsen D C | 2000 | Socio- Economic Planning Sciences2000，34，3： | 1 |
| 20 | Selection of biological control agents for controlling soil and seed - borne diseases in the field显示文摘 | Knudsen I M B Hockenhull J Jensen D K | 1997 | European Journal of Plant Pathology1997，103，： | 1 |
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