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| 1 | 炎症与冠心病:综述显示文摘约半数的心肌梗死患者并没有典型的发病危险因素。这就促使人们去研究其他的致病因素,当存在这些因素时,可帮助预测哪些患者发生心肌梗死和其他心血管疾病的危险度较高。随着对缺血性心脏病发病机制认识的不断提高,人们对动脉粥样硬化和发生心血管疾病危险的潜在标志物也有了新的认识。在最近几年,有大量资料表明,某些炎症的标志物(全身性的和局限性的)在动脉粥样硬化形成过程中起着关键性的作用。更明确地说,C反应蛋白(炎症的一种全身性标志物)水平的升高与心血管疾病发病危险升高密切相关。而且,炎症的标志物(如C反应蛋白)水平升高与已有的治疗方法的疗效之间也有着潜在的重要关系,特别是以肝脏羟甲基戊二酸辅酶A还原酶抑制剂-普伐他汀进行的降脂疗法。本文讨论了动脉粥样硬化的发病机制、内皮功能障碍和斑块破溃的作用以及炎症在其中所起作用的依据。同时,还评述了怎样治疗可减少血管的炎症。 | Koen W | 2002 | 世界医学杂志2002，6，2： | 2 |
| 2 | Chemistry of dissolved in organic carbon in estuarine and coastal brackish waters显示文摘 | Mook W G Koene B K S | 1975 | Estuarine Coastal Marine Science1975，3，： | 1 |
| 3 | Useful estimation procedures for critical gaps 显示文摘 | BRILON W KOENING R TROUTBECK R J | 1999 | Transportation Research Part A1999，，33： | 1 |
| 4 | Stable numerical solutions of the reactor kinetics equations显示文摘 | HANSEN K F KOEN B V LITTLE W W | 1965 | Nucl Sci Eng1965，22，： | 1 |
| 5 | Soybean dis-ease loss estimates for the United States from 1996 to1998显示文摘 | Wrather J A Stienstra W C Koenning S R | 2001 | Can J Plant Pathol2001，23，2： | 1 |
| 6 | Genotype and plasma concen- tration of cystatin C in patients with coronary heart disease and risk for secondary cardiovascular events 显示文摘 | Loew M Hoffmann MM Koening W | 2012 | Arterioseler Thromb Vase Biol2012，25，7： | 1 |
| 7 | Anther developmental defects in Arabidopsis thaliana male - sterile mutants显示文摘 | Paul M S Anhthu Q B Koen W | 1999 | Sex Plant Reprod1999，11，： | 1 |
| 8 | Dynamics of cryptogamic soil crusts in a derived grassland in southeastern Australia显示文摘 | Eldridge D J Semple W S Koen T B | 2000 | Austral Ecology2000，25，3： | 1 |
| 9 | Soybean disease loss estimates for the United States from 1996 to 1998 显示文摘 | Wrather J A Stienstra W C Koenning S R | 2001 | Canadian Journal of Plant Pathology2001，3，： | 1 |
| 10 | C-reactive protein a sensitive marker of inflammation,predicts future risk of coronary heart disease in initially healthy middle-aged men:results from the Monica显示文摘 | Koening W Sund M Froelich M | 1999 | Circulation1999，99，2： | 1 |
| 11 | Traffic accident segmentation by means of latent class clustering显示文摘 | Benoit D Geert W Koen V | 2008 | Accident Analysis and Prevention2008，，40： | 1 |
| 12 | Lipoprotein-associated phospholipase A2 adds to risk prediction of incident coronary events by C-reactive protein in apparently healthy middle-aged men from the general population:results from the 14-year follow-up of a large cohort from southern Germany显示文摘 | KOENING W KHUSEYINOVA N LOWEL H | | 0，，14： | 1 |
| 13 | Soybean dis- ease loss estimates for the United States from 1996 to 1998 显示文摘 | Wrather J A Stienstra W C Koenning S R | 2001 | Canadian Journal of Plant Pathology2001，23，： | 1 |
| 14 | Continuous dcionization of a dilute nickel solution显示文摘 | P B Spoor L Koene W R terVeen | 2002 | Chcmical Engineering Journal2002，89，： | 1 |
| 15 | Efficacy and tolweabibty of felodipine and amlosipine in the treatment of mild bypwetension显示文摘 | Koening W | 1993 | Drug Inveat1993，5，： | 1 |
| 16 | Recent progress in the clinical aspects of fibrinogen显示文摘 | | 1995 | Eur Heart J1995，16，： | 1 |
| 17 | Anther developmental defects in Arabidopsis thaliana male-sterile mutants 显示文摘 | PAUL M S ANHTHU Q B KOEN W K N | 1999 | Sex Plant Reprod1999，11，： | 1 |
| 18 | Association between plasma viscosity and pressure显示文摘 | Koening W | 1991 | Am J Hypertens1991，4，1： | 1 |
| 19 | Soybean disease loss estimates for the United States from 1996 to 1998 显示文摘 | Wrather J A Stienstra W C Koenning S R | 2001 | Canadian Journal of Plant Pathology2001，23，2： | 1 |
| 20 | Berling's Water Harvest显示文摘 | Koening K W | 2000 | Water 212000，，6： | 1 |
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