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| 1 | 用1Hz GPS观测数据推导中强震震源过程的能力:2008年日本岩手—宫城内陆地震例子显示文摘通过反演研究2008年日本岩手—宫城内陆地震(M~6.9),说明了用1Hz全球定位系统(GPS)观测数据推导中强震(M6级)震源过程的能力。比较了此次地震采样率为1Hz的GPS观测波形,发现与强震仪记录波形有很好的一致性。由于震源区及其周围有足够多的GPS台站很好地记录到了地面运动,因而使我们仅仅采用1Hz的GPS观测数据就可进行波形反演。反演的结果与大地测量和强震仪数据联合反演的结果相当一致,如地震矩(Mw~6.9)、累积滑动量分布和破裂传播等。这种一致性证明,采样率为1Hz的GPS观测数据不仅能用来推导M6级中强震破裂过程的动态特征,而且能用来推导其持久(或静态)的滑动。 | Y. Yokota K. Koketsu K. Hikima S. Miyazaki 邵玉平(译) 许健生(校) | 2009 | 世界地震译丛2009，40，5： | 5 |
| 2 | gastrointestinal symptom prevalence depends on disease duration and gastrointestinal region in type 2 diabetes mellitus显示文摘AIM To unravel relationships between gastrointestinal(GI)symptoms impairing quality of life(QOL)and clinical profiles of diabetes mellitus(DM)patients. METHODS We enrolled 134 outpatients with type 2 DM.Mean age was 64.7 years,mean body mass index was 24.7 RESULTS Lower abdominal symptoms were found to be more frequent than those affecting the upper abdomen.Diabetic duration and medications showed associations with GI symptoms.We identified differences in peak prevalences of the five symptoms.Gastralgia(P=0.02vs 10-14 years)and total GI symptoms(P=0.01 and P=0.02 vs 5-9 years and 10-14 years,respectively)peaked at a diabetes duration of 15-19 years.Heartburn(P=0.004)and postprandial fullness(P=0.03)tended to increase with disease duration.Constipation and diarrhea showed bimodal peaks,with the first early and the second late(e.g.,P=0.03 at 15-19 years vs 10-14years for diarrhea)in the disease course.Finally,GI symptoms showed clustering that reflected the region of the GI tract affected,i.e.,constipation and diarrhea had similar frequencies(P<0.0001). CONCLUSION Our study highlights the importance of questioning patients about QOL impairment due to abdominal symptoms,especially in the early and the late periods of diabetes. | Midori Fujishiro Akifumi Kushiyama Hiroki Yamazaki Sunao Kaneko Yuko Koketsu Takeshi Yamamotoya Takako Kikuchi Hideyuki Sakoda Ryo Suzuki Takashi Kadowaki | 2017 | World Journal of Gastroenterology2017，23，36： | 4 |
| 3 | OsIDD2, a zinc finger and INDETERMINATE DOMAIN protein, regulates secondary cell wall formation显示文摘Previously, we found 123 transcription factors(TFs) as candidate regulators of secondary cell wall(SCW)formation in rice by using phylogenetic and co-expression network analyses. Among them, we examined in this work the role of OsIDD_2, a zinc finger and indeterminate domain(IDD) family TF. Its overexpressors showed dwarfism, fragile leaves, and decreased lignin content, which are typical phenotypes of plants defective in SCW formation, whereas its knockout plants showed slightly increased lignin content.The RNA-seq and quantitative reverse transcription polymerase chain reaction analyses confirmed that some lignin biosynthetic genes were downregulated in the OsIDD_2-overexpressing plants, and revealed the same case for other genes involved in cellulose synthesis and sucrose metabolism. The transient expression assay using rice protoplasts revealed that OsIDD_2 negatively regulates the transcription of genes involved in lignin biosynthesis, cinnamyl alcohol dehydrogenase 2 and 3(CAD_2 and 3), and sucrose metabolism, sucrose synthase 5(SUS_5), whereas an Alpha Screen assay, which can detect the interaction between TFs and their target DNA sequences, directly confirmed the interaction between OsIDD_2 and the target sequences located in the promoter regions of CAD_2 and CAD_3. Based on these observations, we conclude that OsIDD_2 is negatively involved in SCW formation and other biological events by downregulating its target genes. | Peng Huang Hideki Yoshida Kenji Yano Shunsuke Kinoshita Kyosuke Kawai Eriko Koketsu Masako Hattori Sayaka Takehara Ji Huang Ko Hirano Reynante Lacsamana Ordonio Makoto Matsuoka Miyako Ueguchi-Tanaka | 2018 | Journal of Integrative Plant Biology2018，60，2： | 3 |
| 4 | Parallel PSM/ FDM Hybrid Simulation of Ground Motions from the 1999 Chi-Chi,Taiwan,Earthquake显示文摘 | Furumura T Koketsu K Wen K L | | 0，，09： | 1 |
| 5 | Reconstruc- tion of the saframycin core scaffold defines dual Pictet-Spengler mechanisms显示文摘 | Koketsu K Watanabe K Suda H | 2010 | Nature Chemical Biology2010，6，6： | 1 |
| 6 | Phenolic and bis-iridoid glycosides from Strychnos cocculoides 显示文摘 | SUNGHWA F KOKETSU M | 2009 | Nat Prod Res2009，23，15： | 1 |
| 7 | Culling intervals and culling risks in four stages of the reproductive life of first ~rvice and reserviced female pigs in commercial herds 显示文摘 | Sasaki Y Koketsu Y | 2010 | Theriogenolo gy2010，73，5： | 1 |
| 8 | Elucidating information processing in primate basal ganglia circuitry:a novel technique for pathway-selective ablation mediated by immunotoxin显示文摘 | Takada M Inoue Kl Koketsu D | | 0，，： | 1 |
| 9 | An IL-1 cytokine member,IL-33, induces human basophil activation via its ST2 receptor显示文摘 | Suzukawa M Iikura M Koketsu R | 2008 | JImmunol2008，181，9： | 1 |
| 10 | Influence of various factors on far-rowing rate on farms using early weaning显示文摘 | Koketsu Y Dial GD King VL | 1997 | J Anim Sci1997，，75： | 1 |
| 11 | 5-Chloroacetyl-2-amino-1,3-selenazoles attenuate microglial inflammatory responses through NF-kappaB inhibition显示文摘 | Nam KN Koketsu M Lee EH | 2008 | Eur J Pharmacol2008，589，13： | 1 |
| 12 | Factors influencing the postweaning reproductive performance of sows on commercial farms显示文摘 | KOKETSU Y DIAL G D | 1997 | Theriogenology1997，47，7： | 1 |
| 13 | A seismological overview of long-period ground motion显示文摘 | Kazuki Koketsu Hiroe Miyake | 2008 | Journal of Seismology2008，，2： | 1 |
| 14 | An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor 显示文摘 | Suzukawa M Iikura M Koketsu R | 2008 | J Immunol2008，181，9： | 1 |
| 15 | Phenolic and bis-iridoid glyco- sides from Strychnos cocculoides 显示文摘 | Sunghwa F Koketsu M | 2009 | Natural Product Research2009，，15： | 1 |
| 16 | Response spectral attenuation relalionships for Sumatran-subduction earthquakes and the seismic hazard implications to Singapore and Kuala Lumpur显示文摘 | MEGAWATI K PAN T C KOKETSU K | 2005 | Soil Dynamics and Earthquake Engineering2005，25，1： | 1 |
| 17 | Inhibition of tyrosinase activity by N,N-unsubstituted selenourea derivatives显示文摘 | Ha SK Koketsu M Lee K | | 0，，： | 1 |
| 18 | Biologically sig- nificant selenium-containing heterocycles显示文摘 | Ninomiya M Garud D R Koketsu M | 2011 | Coordi- nation Chemistry Reviews2011，255，2324： | 1 |
| 19 | Factors influencing the postweaning re- productive performance of sows on commercial farms显示文摘 | Koketsu Y Dial G D | 1997 | Theri- ogenology1997，47，7： | 1 |
| 20 | Pretreatment with intraventricular basic fibroblast growth factor decreases infarct size following focal cerebral ischemia in rats显示文摘 | Koketsu N Berlove DJ Moskowitz MA | 1994 | Ann Neurol1994，5，4： | 1 |
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