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| 1 | Transjugular intrahepatic portosystemic shunt for the management of acute variceal hemorrhage显示文摘Acute variceal hemorrhage,a life-threatening condition that requires a multidisciplinary approach for effective therapy,is defined as visible bleeding from an esophageal or gastric varix at the time of endoscopy,the presence of large esophageal varices with recent stigmata of bleeding,or fresh blood visible in the stomach with no other source of bleeding identified.Transfusion of blood products,pharmacological treatments and early endoscopic therapy are often effective;however,if primary hemostasis cannot be obtained or if uncontrollable early rebleeding occurs,transjugular intrahepatic portosystemic shunt(TIPS)is recommended as rescue treatment.The TIPS represents a major advance in the treatment of complications of portal hypertension.Acute variceal hemorrhage that is poorly controlled with endoscopic therapy is generally well controlled with TIPS,which has a 90%to 100%success rate.However,TIPS is associated with a mortality of 30%to 50%in such a setting.Emergency TIPS should be considered early in patients with refractory variceal bleeding once medical treatment and endoscopic sclerotherapy failure,before the clinical condition worsens.Furthermore,admission to specialized centers is mandatory in such a setting and regional protocols are essential to be organized effectively.This review article discusses initial management and then focuses on the specific role of TIPS as a primary therapy to control acute variceal hemorrhage,particularly as a rescue therapy following failure of endoscopic approaches. | Romaric Loffroy Louis Estivalet Violaine Cherblanc Sylvain Favelier Pierre Pottecher Samia Hamza Anne Minello Patrick Hillon Pierre Thouant Pierre-Henri Lefevre Denis Krausé Jean-Pierre Cercueil | 2013 | World Journal of Gastroenterology2013，19，37： | 25 |
| 2 | 神经探测仪在甲状腺手术中的应用与评价显示文摘目的探索甲状腺复杂手术中应用神经探测仪探寻和保护喉返神经的方法。方法应用神经探测仪在 2 0例复杂甲状腺手术中探寻和保护喉返神经。结果 2 0例复杂甲状腺手术患者术后无一例出现喉返神经受损的临床症状。结论神经探测仪应用于复杂的甲状腺手术中 ,对于保护喉返神经免于误伤有着较大的临床意义。其方法简便易行 ,可靠有实效。 | 潘凯 Gebhardt C Kraus D | 2003 | 中华普通外科杂志2003，18，12： | 24 |
| 3 | 重新审视中国高龄老人血压与死亡风险之间的关系:以社区为基础的纵向前瞻性队列研究显示文摘目的探讨中国高龄老人血压与3年全因死亡风险和死因别死亡风险之间的关系。研究设计以社区为基础的纵向前瞻性队列研究。研究地点2011和2014年在中国22个省份开展的两轮中国老年健康影响因素跟踪调查。研究对象4658名高龄老人(平均年龄为92.1岁)。主要结局指标随访3年全因死亡和死因别死亡。结果经过3年的随访,共计1977人死亡,收缩压(SBP)、平均动脉压(MAP)、脉压差(PP)与死亡风险间呈U型关系,SBP、MAP和PP在143.5、101和66mmHg时死亡风险最低。对混杂因素进行调整后,仅SBP与死亡风险的U型关系存在,风险最低点为129mmHg。与129mmHg的人群相比,SBP低于107mmHg时,死亡风险随SBP的升高而降低[风险比(HR)从1.47(1.01~2.17)到1.08(1.01~1.17)1;SBP高于154mmHg时,死亡风险随SBP的升高而增加[HR从1.08(1.01~1.17)到1.27(1.02~1.58)]。在死因别分析中,与中等水平SBP(107~154mmHg)相比,高水平的SBP(〉154mmHg)与心血管疾病(CVD)死亡风险升高相关联[调整HR1.51(1.12~2.02)];低水平SBP(〈107mmHg)与非CVD死亡风险升高相关联[调整HR1.58(1.26~1.98)]。在敏感性分析与亚组分析中血压与死亡风险的U型关系保持不变。结论研究在中国高龄老人中发现SBP与3年全因死亡风险呈U型关系,高SBP意味着更高的CVD死亡风险,低SBP意味着更高的非CVD死亡风险。这提示高龄老人目前的血压管理理念有待重新评估,可能需要针对这一特殊人群制定特定的血压指南。 | 吕跃斌 高翔 殷召雪 陈华帅 罗杰斯 Melanie Sereny Brasher Virginia Byers Kraus 李湉湉 曾毅 施小明 张希如(译) 毛琛(校) | 2018 | 英国医学杂志中文版2018，21，8： | 17 |
| 4 | Endovascular management of visceral artery aneurysms: When to watch, when to intervene?显示文摘Visceral artery aneurysms(VAA) include splanchnic and renal artery aneurysms. They represent a rare clinical entity, although their detection is rising due to an increased use of cross-sectional imaging. Rupture is the most devastating complication, and is associated with a high morbidity and mortality. In addition, increased percutaneous endovascular interventions have raised the incidence of iatrogenic visceral artery pseudoaneurysms(VAPAs). For this reason, elective repair is preferable in the appropriately chosen patient. Controversy still exists regarding their treatment. Over the past decade, there has been steady increase in the utilization of minimally invasive, non-operative interventions, for vascular aneurysmal disease. All VAAs and VAPAs can technically be fixed by endovascular techniques but that does not mean they should. These catheter-based techniques constitute an excellent approach in the elective setting. However, in the emergent setting it may carry a higher morbidity and mortality. The decision for intervention has to take into account the size and the natural history of the lesion, the risk of rupture, which is high during pregnancy, and the relative risk of surgical or radiological intervention. For splanchnic artery aneurysms, we should recognize that we are not, in reality, well informed about their natural history. For most asymptomatic aneurysms, expectant treatment is acceptable. For large, symptomatic or aneurysms with a high risk of rupture, endovascular treatment has become the firstline therapy. Treatment of VAPAs is always mandatory because of the high risk of rupture. We present our point of view on interventional radiology in the splanchnic arteries, focusing on what has been achieved and the remaining challenges. | Romaric Loffroy Sylvain Favelier Pierre Pottecher Pierre-Yves Genson Louis Estivalet Sophie Gehin Jean-Pierre Cercueil Denis Krausé | 2015 | World Journal of Radiology2015，7，7： | 11 |
| 5 | Psychiatric side effects of pegylated interferon alfa-2b as compared to conventional interferon alfa-2b in patients with chronic hepatitis C显示文摘AIM: To assess systematically the spectrum and extent of depressive symptoms comparing patient groups receiving peginterferon or conventional interferon.METHODS: Ninety-eight patients with chronic hepatitis C and interferon-based therapy (+ribavirin) were consecutively enrolled in a longitudinal study. Patients were treated with conventional interferon alfa-2b (48/98patients; 5 MIU interferon alfa-2b thrice weekly) or peginterferon alfa-2b (50/98 patients; 80-150 μgpeginterferon alfa-2b) in combination with weight-adapted ribavirin (800-1 200 mg/d). Repeated psychometric testing was performed before, three times during and once after antiviral therapy: Depression was evaluated by the Hospital Anxiety and Depression Scale (HADS), anger/hostility by the Symptom Checklist-90 Items Revised (SCL-90-R).RESULTS: Therapy with pegylated interferon alfa-2bproduces comparable scores for depression (ANOVA:P = 0.875) as compared to conventional interferon.Maximums of depression scores were even higher and cases of clinically relevant depression were frequent during therapy with peginterferon. Scores for anger/hostility were comparable for both therapy subgroups.CONCLUSION: Our findings suggest that the extent and frequency of depressive symptoms in total are not reduced by peginterferon. Monitoring and management of neuropsychiatric toxicity especially depression have to be considered as much as in antiviral therapy with unmodified interferon. | Michael R Kraus Arne Sch(a|¨)fer Herbert Csef Michael Scheurlen | 2005 | World Journal of Gastroenterology2005，11，12： | 5 |
| 6 | Determination of terrain models in wooded areas with airborne laser scanner data显示文摘 | K. Kraus N. Pfeifer | 1998 | ISPRS Journal of Photogrammetry and Remote Sensing1998，，4： | 3 |
| 7 | 从优秀到卓越——机电一体化技术与气动技术的结合显示文摘机电一体化技术的发展令各种传动装置有了更多的同一性。因此,在今天与电子机械的竞争中。气动传动装置重新焕发出了其本来的优势。 | Josef Kraus | 2007 | 现代制造2007，，18： | 3 |
| 8 | 经常服用鱼油补充剂与心血管疾病结局和全因死亡风险之间的关系:基于大型人群队列研究的证据显示文摘目的在一个大型的前瞻性队列中探讨经常服用鱼油补充剂与心血管疾病(CVD)及死亡风险之间的关系。研究设计基于人群的前瞻性队列研究。研究背景英国生物银行。研究对象在2006—2010年期间,共招募427678名在基线时没有CVD或癌症病史且年龄在40~69岁之间的男性和女性,并一直随访至2018年底。主要暴露所有研究对象均回答了经常服用补充剂(包括鱼油)的情况。主要结局指标全因死亡风险、CVD死亡风险和CVD事件。结果在基线时,427678名研究对象中有133438名(31.2%)报告了有经常服用鱼油补充剂的情况。经常服用鱼油补充剂与不服用鱼油补充剂的研究对象经多变量校正后的风险比(HR)值(95%可信区间)分别为:全因死亡风险0.87(0.83~0.90),CVD死亡风险0.84(0.78~0.91),CVD事件0.93(0.90~0.96)。经常服用鱼油补充剂与CVD事件之间的关联在高血压人群中似乎更强(交互P值=0.005)。结论经常服用鱼油补充剂可降低全因及心血管疾病的死亡风险,并对心血管疾病事件具有边际保护作用。 | 李志浩 钟文芳 刘思敏 Kraus Virginia Byers 张宇杰 高翔 吕跃斌 申动 张希如 张沛东 黄清湄 陈清 吴娴波 施小明 王冬 毛琛 | 2020 | 英国医学杂志中文版2020，23，6： | 3 |
| 9 | Natural Variation in Tomato Reveals Differences in the Recognition of AvrPto and AvrPtoB Effectors from Pseudomonas syringae显示文摘从茄属 pimpinellifolium 的 Pto 蛋白质 kinase 与 Pseudomonas syringae 受动器 AvrPto 或 AvrPtoB 交往激活被触发受动器的免疫。AvrPto-Pto 和 AvrPtoB-Pto 建筑群的以前解决的水晶结构表明 Pto 通过两个绑每个受动器一分享并且一个唯一的接口。这里,我们在西红柿的野种类使用自然变化进一步调查这二个受动器的 Pto 识别。一种,茄属 chmielewskii,被发现有认出仅仅 AvrPtoB 的许多就职。从这些就职之一的 Pto ortholog 在 AvrPto 特定的接口为 AvrPtoB 的识别负责,它由仅仅 14 氨基酸不同于茄属 pimpinellifolium Pto,包括二, glutamate-49/glycine-51。在 Pto (histidine-49/valine-51 ) 把这二残余变换成那些没恢复 AvrPto 的识别。随后的实验表明在在 Pto 的位置 193 点的 histidine-to-aspartate 的单个替换,不在 AvrPto 特定的接口附近,为在植物房间授与 AvrPto 的识别是足够的。在 Pto 的 aspartate-to-histidine-193 的相互的替换废除了 AvrPto 识别,证实这残余的重要性。我们的结果由 Pto 关于受动器识别揭示新方面并且表明使用自然变化理解在抵抗蛋白质和病原体受动器之间的相互作用的价值。 | Christine M. Kraus Kathy R. Munkvold Gregory B. Martin | 2016 | Molecular Plant2016，9，5： | 2 |
| 10 | Omentum facilitates liver regeneration显示文摘AIM:To investigate the mechanism of liver regeneration induced by fusing the omentum to a small traumatic injury created in the liver. We studied three groups of rats. In one group the rats were omentectomized; in another group the omentum was left in situ and was not activated,and in the third group the omentum was activated by polydextran particles. METHODS:We pre-activated the omentum by injecting polydextran particles and then made a small wedge wound in the rat liver to allow the omentum to fuse to the wound. We monitored the regeneration of the liver by determining the ratio of liver weight/body weight,by histological evaluation (including immune staining for cytokeratin-19,an oval cell marker),and by testing for developmental gene activation using reverse transcription polymerase chain reaction (RT-PCR). RESULTS:There was no liver regeneration in the omentectomized rats,nor was there significant regeneration when the omentum was not activated,even though in this instance the omentum had fusedwith the liver. In contrast,the liver in the rats with the activated omentum expanded to a size 50% greater than the original,and there was histologically an interlying tissue between the wounded liver and the activated omentum in which bile ducts,containing cytokeratin-19 positive oval cells,extended from the wound edge. In this interlying tissue,oval cells were abundant and appeared to proliferate to form new liver tissue. In rats pre-treated with drugs that inhibited hepatocyte growth,liver proliferation was ongoing,indicating that regeneration of the liver was the result of oval cell expansion. CONCLUSION:Activated omentum facilitates liver regeneration following injury by a mechanism that depends largely on oval cell proliferation. | Ashok K Singh Nishit Pancholi Jilpa Patel Natalia O Litbarg Krishnamurthy P Gudehithlu Perianna Sethupathi Mark Kraus George Dunea Jose AL Arruda | 2009 | World Journal of Gastroenterology2009，15，9： | 2 |
| 11 | 超深井钻进施工经验显示文摘 | Kraus,W 李在民 | 1994 | 探矿工程译丛1994，，3： | 2 |
| 12 | 现代液压技术的新发展显示文摘继阀门控制和伺服技术之后,液压技术中又展开了数字调节电子技术和高分辨率传感技术的融合。对于机床来说,这一方面可以提高液压驱动的竞争力,另一方面又可以提高液压驱动装置的工作效率。 | Josef Kraus | 2005 | 现代制造2005，，28： | 2 |
| 13 | Transcatheter Arterial Embolization of Splenic Artery Aneurysms and Pseudoaneurysms: Short- and Long-Term Results显示文摘 | Romaric Loffroy Boris Guiu Jean-Pierre Cercueil C?me Lepage Nicolas Cheynel Eric Steinmetz Frédéric Ricolfi Denis Krausé | 2008 | Annals of Vascular Surgery2008，，5： | 2 |
| 14 | Material differentiation by dual energy CT: initial experience显示文摘 | Thorsten R. C. Johnson Bernhard Krau? Martin Sedlmair Michael Grasruck Herbert Bruder Dominik Morhard Christian Fink Sabine Weckbach Miriam Lenhard Bernhard Schmidt Thomas Flohr Maximilian F. Reiser Christoph R. Becker | 2007 | European Radiology2007，，6： | 2 |
| 15 | Open wedge re-correction high tibial osteotomy in an elderly patient with a varus angulated non-united dome-shaped high tibial osteotomy显示文摘The high tibial osteotomy(HTO)is a wellestablished and commonly used treatment for younger and active patients with a medial unicompartmental osteoarthritis of the knee and varus malalignment.The aim of this technique is to shift the load to a functional lateral compartment in order to delay total knee arthroplasty.The dome-shaped HTO was introduced by Blaimont et al.(1975)and later popularized by Maquet(1980).Out of 118 cases,96 cases of overcorrection,13 cases of undercorrection,and 9 cases | Steffen SCHROTER Lukas KONSTANTINIDIS Tobias M. KRAUS Fabian STUBY Ulrich STOCKLE Thomas FREUDE | 2013 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2013，14，11： | 2 |
| 16 | 滚道输送 谁停谁行显示文摘采用滚道输送机可以很容易实现物流的顺畅运行。从物流配送的角度上看,这种输送机比胶带 输送机和链式输送机更具优势。但这种输送机只限于对物流工作进行最佳化的调整。 | Josef Kraus | 2004 | 现代制造2004，，19： | 2 |
| 17 | Associations of Sarcopenia, Handgrip Strength and Calf Circumference with Cognitive Impairment among Chinese Older Adults显示文摘Objective To evaluate the associations of sarcopenia,handgrip strength and calf circumference with cognitive impairment among Chinese older adults.Methods Totally 2,525 older adults were recruited from the Healthy Aging and Biomarkers Cohort Study.Cognitive impairment was assessed by the Chinese Mini-Mental State Examination.Handgrip strength was calculated from the means of the right and left hand values.Calf circumference was measured at the site of maximum circumference of the non-dominant leg.The formula developed by Ishii was used to define sarcopenia.Multiple logistic regression was performed to evaluate the associations of sarcopenia,handgrip strength,and calf circumference with cognitive impairment.Results The prevalence of cognitive impairment was 34.36%.The adjusted odds ratio(OR)for cognitive impairment in individuals with sarcopenia was 2.55[95% confidence interval(95%CI):1.86-3.50].Compared with individuals in the first quartile(Q1)of calf circumference,the adjusted ORs in the second,third,and fourth quartiles(Q_(2),Q_(3),and Q_(4))were 0.75(95% CI:0.58-0.96),0.59(95% CI:0.44-0.79),and 0.62(95% CI:0.45-0.8),respectively.Compared with individuals in Q1 of handgrip strength,the adjusted ORs for Q_(2),Q_(3),and Q_(4) were 0.49(95%CI:0.38-0.62),0.31(95% CI:0.23-0.41),and 0.30(95%CI:0.21-0.44),respectively.Conclusion Sarcopenia,identified by low handgrip strength and low calf circumference,was positively associated with cognitive impairment. | WU Bing LYU Yue Bin CAO Zhao Jin WEI Yuan SHI Wan Ying GAO Xiang ZHOU Jin Hui KRAUS Virginia Byers ZHAO Feng CHEN Xin LU Feng ZHANG Ming Yuan LIU Ying Chun TAN Qi Yue SONG Shi Xun QU Ying Li ZHENG Xu Lin SHEN Chong MAO Chen SHI Xiao Ming | 2021 | Biomedical and Environmental Sciences2021，34，11： | 2 |
| 18 | Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPAR gamma显示文摘 | Zander T Kraus JA Grommes C | 2002 | J Neurochem2002，81，： | 2 |
| 19 | Fatal and hospitalized injuries resulting from the 1994 Northridge earthquake显示文摘 | Peek-Asa C Kraus JF Bourque LB | 1998 | Int J Epidemiol1998，27，3： | 1 |
| 20 | Srglcal access to tumors of the cervieothracic Junction 显示文摘 | Kraus Dh Huo J Burr M | 1995 | Head Neck1995，17，： | 1 |
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