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28篇 您的检索式:作者名="Kremling"
    题名 作者 年代 出处 被引量
1Differential expression of chemokines and chemokine receptors during microglial activation and inhibition显示文摘KREMLE V SERGEY G ROBERTS REBECCA L 2004J Neuroimmunology2004,12,149:1
2Context-dependent adaption of EpCAM expression in early systemic esophageal cancer 显示文摘Driemel C Kremling H Schumacher S 2014Oncogene2014,33,49:1
3Determination of peripros thetie bone density with the DEXA method after implantation of cuatom-made uncemented femoral stems显示文摘Martini F Sell S Kremling E 1996Int Orthop1996,4,:1
4Saharan dust influenced trace element fluxes in deep North Atlantic subtropical waters显示文摘Kremling K Streu P 1993Deep Sea Research1993,40,6:1
5Saharan dust influenced trace element fluxes in deep North Atlantic subtropical wasters显示文摘Kremling K Sreu P 1993Deep Sea Research1993,40,6:1
6Particulate trace element fluxes in the deep northeast Atlantic Ocean 显示文摘KUSS J KREMLING K 1999Deep-Sea Research I1999,46,:1
7A comparison offish oil,flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers显示文摘Kaul N Kreml R Austria J 2008Am Coil Nutr2008,27,:1
8Saharan dust influenced trace element fluxes in deep North Atlantic subtropical waters显示文摘Kremling K Sreu P 1993Deep Sea Research1993,40,6:1
9Context-dependent adaption of Ep CAM expression in early systemic esophageal cancer显示文摘Driemel C Kremling H Schumacher S 2014Oncogene2014,33,41:1
10Mouse proacrosin gene : Nucleotide sequence, diploid expression, and chromosomal localization显示文摘Kremling H Keime S Wilhelm K 1991Genomics1991,11,4:1
11Saharan dust influenced trace element fluxes in deep North Atlantic Subtropical waters显示文摘Kremling K Streu P 1993Deep Sea Research1993,40,6:1
12Context-dependentadaption of EpCAM expression in early systemic esophageal cancer 显示文摘Driemel C Kremling H Schumacher S 2014Oncogene2014,33,41:1
13Symtomatic bucket handle tear of the lateral meniscus after total knee arthmplasty 显示文摘Martini F Kremling F Kunz W 1999Int Orthop1999,23,5:1
14The genes for protamine 1 and 2 (PRM1 and PRM2) and transition protein 2 (TNP2) are closely linked in the mammalian genome显示文摘Engel W Keime S Kremling H 1992Cytogenet Cell Genet1992,61,2:1
15System Biology 显示文摘A Kremling J saez - Rodriguez 2007Journal of Biotechnology2007,129,2:1
16Cultivation of lacrimal gland acinar cells in a microgravity environment显示文摘Schrader S Kremling C Klinger M 0,,08:1
17In-Depth Computational Analysis of Natural and Artificial Carbon Fixation Pathways显示文摘In the recent years,engineering new-to-nature CO_(2)-and C1-fixing metabolic pathways made a leap forward.New,artificial pathways promise higher yields and activity than natural ones like the Calvin-Benson-Bassham(CBB)cycle.The question remains how to best predict their in vivo performance and what actually makes one pathway“better”than another.In this context,we explore aerobic carbon fixation pathways by a computational approach and compare them based on their specific activity and yield on methanol,formate,and CO_(2)/H_(2)considering the kinetics and thermodynamics of the reactions.Besides pathways found in nature or implemented in the laboratory,this included two completely new cycles with favorable features:the reductive citramalyl-CoA cycle and the 2-hydroxyglutarate-reverse tricarboxylic acid cycle.A comprehensive kinetic data set was collected for all enzymes of all pathways,and missing kinetic data were sampled with the Parameter Balancing algorithm.Kinetic and thermodynamic data were fed to the Enzyme Cost Minimization algorithm to check for respective inconsistencies and calculate pathway-specific activities.The specific activities of the reductive glycine pathway,the CETCH cycle,and the new reductive citramalyl-CoA cycle were predicted to match the best natural cycles with superior productsubstrate yield.However,the CBB cycle performed better in terms of activity compared to the alternative pathways than previously thought.We make an argument that stoichiometric yield is likely not the most important design criterion of the CBB cycle.Still,alternative carbon fixation pathways were paretooptimal for specific activity and product-substrate yield in simulations with C1 substrates and CO_(2)/H_(2)and therefore hold great potential for future applications in Industrial Biotechnology and Synthetic Biology.Hannes Löwe Andreas Kremling 2021BioDesign Research2021,,1:1
18Saharan dust influenced trace element fluxes in deep north atlantic subtropical waters显示文摘Kremling K Streu P 1993Deep Sea Research1993,40,6:1
19Saharan dust influenced trace element fluxes in deep North Atlantic Subtropical waters显示文摘Kremling K Streu P 1993Deep Sea Research1993,40,6:1
20Synoptic survey on dissolved trace metal levels in Baltic surface waters显示文摘Kremling K Petersen H 1984Marine Pollution Bulletin1984,15,9:1
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